Abstract: A grommet body of a grommet includes: a large-diameter tubular portion; a first small-diameter tubular portion arranged on one side of a through-hole; and a second small-diameter tubular portion arranged on another side of the through-hole. The grommet body includes an umbrella-like sound insulation portion which covers the through-hole from another side, and the sound insulation portion is configured such that an abutting side surface is folded back in such a way as to face a radial outer side of the grommet body with a folded-back portion as a base point. The sound insulation portion in a state in which the abutting side surface is folded back in such a way as to face the radial outer side of the grommet body has a pleated shape, and an outer diameter of the sound insulation portion in this state is smaller than an inner diameter of the through-hole.

Abstract: An impedance matching device comprising a variable reactor having a main winding and control winding, wherein a generated magnet field in the core is an AC magnetic field with a magnitude exceeding a value to settle a deviation between a control target value for impedance matching and a feedback value, by changing the magnitude of the generated magnetic field by changing a control current passing through the control winding, thereby controlling inductance of the variable rector to be a predetermined value to perform impedance matching, the response delay in the impedance matching is reduced by reducing a response delay in the inductance variation of the variable reactor.

Abstract: An impedance matching device comprising a variable reactor having a main winding and control winding, wherein a generated magnet field in the core is an AC magnetic field with a magnitude exceeding a value to settle a deviation between a control target value for impedance matching and a feedback value, by changing the magnitude of the generated magnetic field by changing a control current passing through the control winding, thereby controlling inductance of the variable rector to be a predetermined value to perform impedance matching, the response delay in the impedance matching is reduced by reducing a response delay in the inductance variation of the variable reactor.

Abstract: An analog front-end circuit for measurement used as an interface between a sensor and a control device includes: an isolated part including at least an AD conversion circuit configured to serve as an interface to the sensor; a non-isolated part including at least a control circuit configured to serve as an interface to the control device; and an isolated communication unit configured to perform isolated half-duplex communication between the isolated part and the non-isolated part. The control circuit is configured to transmit an AD conversion instruction to the AD conversion circuit after providing setting for measurement to the isolated part via the isolated communication unit, obtain a result of AD conversion by the AD conversion circuit from the isolated part via the isolated communication unit, and transfer the obtained AD conversion result to the control device.

Abstract: As a lipid metabolism improving agent for allowing lipids in the body to be metabolized efficiently, a lipid metabolism improving agent containing a pine bark extract as an active component is provided. The lipid metabolism improving agent of the present invention has abilities to promote cholesterol excretion, inhibit lipid absorption, reduce body fat, and inhibit fat accumulation, and the like.

Abstract: A laser machining apparatus in which three or more beam splits are made incident on one machining lens so that high speed machining can be achieved, and the machining quality (shapes, dimensions, accuracy and straightness of machined holes) is excellent. The optical paths of beams A and B having the same polarization direction are aligned almost in one and the same direction by a total reflection/transmission type beam combining means 31c using a difference in incident angle. After that, the optical paths of the beams A and B and the optical path of a beam C different in polarization direction therefrom are aligned almost in one and the same direction by a polarizing type beam combining means 32. Then, the beams A, B and C are made incident on a machining lens 45.

Abstract: Provided is a mold clamping apparatus of a mold having a side wall portion of cantilever shape, by which deformation of the mold side wall portion can be efficiently suppressed. An injection molding machine and injection molding method both using the mold clamping apparatus are also provided. Thereby, molded articles with high quality having no flash generation can be obtained. The mold clamping apparatus comprises a side pusher comprising a pair of supports respectively arranged between adjacent two tie bars out of a plurality of tie bars at positions symmetrical to each other and slidably supported to the tie bars, a moving and positioning means linking the supports to a fixed platen or movable platen and moving the supports to be positioned at a predetermined position and a lateral clamping means provided on each of the pair of supports to push a side face of a fixed mold or movable mold.

Abstract: Provided is a mold clamping apparatus of a mold having a side wall portion of cantilever shape, by which deformation of the mold side wall portion can be efficiently suppressed. An injection molding machine and injection molding method both using the mold clamping apparatus are also provided. Thereby, molded articles with high quality having no flash generation can be obtained. The mold clamping apparatus comprises a side pusher comprising a pair of supports respectively arranged between adjacent two tie bars out of a plurality of tie bars at positions symmetrical to each other and slidably supported to the tie bars, a moving and positioning means linking the supports to a fixed platen or movable platen and moving the supports to be positioned at a predetermined position and a lateral clamping means provided on each of the pair of supports to push a side face of a fixed mold or movable mold.

Abstract: The present invention provides an antibody which specifically recognizes an epitope containing a part of a domain based on a finding that the domain ranging from the 269- to 315-positions of human CD14 represented by SEQ ID NO:1 is a site capable of interacting with another protein, an antibodies provided. This antibody can inhibit the interaction between human CD14 and another protein and thus suppress cell activation. And also, the present invention provides hybridomas producing the above antibody or its fragment; a peptide containing the amino acids in the domain as specified above; a method of constructing an antibody with the use of this peptide as an immunogen; and a method of screening a medicament for sepsis involving the step of bringing a test substance into contact with CD14 and TLR.

Abstract: The present invention provides a water-soluble conjugate consisting of proanthocyanidins and a peptide containing three or more amino acids. Preferably, the average molecular weight of the peptide is not more than 7,000. The water-soluble conjugate of the present invention provides proanthocyanidins having a high protective stability and retained or increased bioactivities. Namely, it does not cause precipitation even in a long-term storage and can be transported into the body while maintaining the bioactivities.

Abstract: The present invention provides a composition for the oral cavity that comprises a pine bark extract that is extracted from the bark of a pine. The composition for the oral cavity of the present invention can provide a plurality of effects such as an effect of improving blood flow in the mouth and an effect of reducing halitosis.

Abstract: A laser machining apparatus in which three or more beam splits are made incident on one machining lens so that high speed machining can be achieved, and the machining quality (shapes, dimensions, accuracy and straightness of machined holes) is excellent. The optical paths of beams A and B having the same polarization direction are aligned almost in one and the same direction by a total reflection/transmission type beam combining means 31c using a difference in incident angle. After that, the optical paths of the beams A and B and the optical path of a beam C different in polarization direction therefrom are aligned almost in one and the same direction by a polarizing type beam combining means 32. Then, the beams A, B and C are made incident on a machining lens 45.

Abstract: A laser processing apparatus is capable of making an axis of a processed hole vertical and providing flexibility for a location of deflecting means by positioning a laser beam output from a laser oscillator at a designed deflection point of an f&thgr; lens. An optical correction system is provided between a first mirror which is freely rotatable around an axis M, and a second mirror which is freely rotatable around an axis N, so that the laser beam deflected by the first mirror is applied to a center of the second mirror. The correction optical system comprises, for example, two convex lenses having a focal length of f1, the distance between centers of the convex lenses being set to 2f1. The distance between centers of the first and second mirrors is set to 4f1.

Abstract: The present invention provides an anti-CD14 antibody and fragments thereof that have a function of inhibiting the binding between CD14 and Toll Like Receptor (TLR). And also hybridomas producing the antibody or fragments thereof, peptides, method of preparing antibodies, CD14 mutant polypeptide, method of screening medicaments for treating sepsis and pharmaceutical compositions for sepsis were provided.

Abstract: The present invention provides an antibody which specifically recognizes an epitope containing a part of a domain based on a finding that the domain ranging from the 269- to 315-positions of human CD14 represented by SEQ ID NO:1 is a site capable of interacting with another protein, an antibodies provided. This antibody can inhibit the interaction between human CD14 and another protein and thus suppress cell activation. And also, the present invention provides hybridomas producing the above antibody or its fragment; a peptide containing the amino acids in the domain as specified above; a method of constructing an antibody with the use of this peptide as an immunogen; and a method of screening a medicament for sepsis involving the step of bringing a test substance into contact with CD14 and TLR.

Abstract: A water quality meter is composed of a plurality of water quality monitoring meters including analyzing units for analyzing water samples introduced from a water distribution pipe, each analyzing unit analyzing the water samples and a measuring cell, and a liquid introducing unit integrated with the analyzing units, which is composed of a single member in which a plurality of fluid flow paths for feeding various types of liquid including the water sample into the analyzing unit are formed. Furthermore, the cells and the plurality of three-dimensional fluid flow paths formed in the single member are fabricated by a micro-fabrication technique using photo-curing resin.

Abstract: A water quality meter is composed of a plurality of analyzing units for analyzing water samples introduced from a water distribution pipe, each analyzing unit including a reagent mixing cell and a measuring cell, and a liquid introducing unit integrated with the analyzing units, which is composed of a single member in which a plurality of fluid flows paths for feeding various types of liquid including the water sample into the analyzing unit are formed. Furthermore, the cells and the plurality of three-dimensional fluid flow paths formed in the single member are fabricated by a micro-fabrication technique using photo-curing resin. In one embodiment, a photometer is situated in the flow path in at least one analyzing unit for measuring absorbency of the liquid. In another embodiment, a pair of electrodes, for measuring electric conductivity or pH, is disposed in a measurement flow path in at least one of the analyzing units.

Abstract: A water quality meter is composed of a plurality of analyzing units for analyzing water samples introduced from a water distribution pipe, each analyzing unit including a reagent mixing cell and a measuring cell, and a liquid introducing unit integrated with the analyzing units, which is composed of a single member in which a plurality of fluid flow paths for feeding various types of liquid including the water sample into the analyzing unit are formed. Furthermore, the cells and the plurality of three-dimensional fluid flow paths formed in the single member are fabricated by a micro-fabrication technique using photo-curing resin.

Abstract: A water quality meter is composed of a plurality of analyzing units for analyzing water samples introduced from a water distribution pipe, each analyzing unit including a reagent mixing cell and a measuring cell, and a liquid introducing unit integrated with the analyzing units, which is composed of a single member in which a plurality of fluid flow paths for feeding various types of liquid including the water sample into the analyzing unit are formed. Furthermore, the cells and the plurality of three-dimensional fluid flow paths formed in the single member are fabricated by a micro-fabrication technique using photo-curing resin.

Abstract: A water quality meter is composed of a plurality of analyzing units for analyzing water samples introduced from a water distribution pipe, each analyzing unit including a reagent mixing cell and a measuring cell, and a liquid introducing unit integrated with the analyzing units, which is composed of a single member in which a plurality of fluid flow paths for feeding various types of liquid including the water sample into the analyzing unit are formed. Furthermore, the cells and the plurality of three-dimensional fluid flow paths formed in the single member are fabricated by a micro-fabrication technique using photo-curing resin.