Patents by Inventor Sajiv K. Nair

Sajiv K. Nair has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 4-oxo-4,7-dihydrofuro[2,3-b]pyridine-5-carboxamide antiviral agents
    Patent number: 6878705
    Abstract: The invention provides a compound of formula I: wherein G, R2, R3, and R4 have any of the values defined in the specification, or a pharmaceutically acceptable salt thereof, as well as processes and intermediates useful for preparing such compounds or salts, and methods of treating a herpesvirus infection using such compounds or salts.
    Type: Grant
    Filed: January 14, 2003
    Date of Patent: April 12, 2005
    Assignee: Pfizer
    Inventors: Michele M. Cudahy, Mark E. Schnute, Steven P. Tanis, William R. Perrault, Paul Matthew Herrinton, Sajiv K. Nair
  • 4-OXO-4,7-DIHYDROFURO[2,3-B]PYRIDINE-5-CARBOXAMIDE ANTIVIRAL AGENTS
    Publication number: 20040259907
    Abstract: The invention provides a compound of formula I: 1
    Type: Application
    Filed: January 14, 2003
    Publication date: December 23, 2004
    Inventors: Michele M. Cudahy, Mark E. Schnute, Steven P. Tanis, William R. Perrault, Paul Matthew Herrinton, Sajiv K. Nair
  • Heteroaryl-ethanolamine derivatives as antiviral agents
    Publication number: 20040110787
    Abstract: The present invention provides a compound of formula as described herein, which are useful as antiviral agents, in particular, as agents against viruses of the herpes family.
    Type: Application
    Filed: August 27, 2003
    Publication date: June 10, 2004
    Inventors: Mark E. Schnute, Michele M. Cudahy, David John Anderson, Thomas M. Judge, Thomas J. Fleck, Paul Matthew Herrinton, Sajiv K. Nair, Allen Scott, William R. Perrault, Steve P. Tanis, James A. Nieman, Sarah A. Collier, Bruce F. Fleck
  • Pyrroloquinolones as antiviral agents
    Patent number: 6683181
    Abstract: The present invention provides a compound of formula I which is useful as antiviral agents, in particular, as agents against viruses of the herpes family.
    Type: Grant
    Filed: November 5, 2002
    Date of Patent: January 27, 2004
    Assignee: Pharmacia and Upjohn Comapny
    Inventors: Valerie A. Vaillancourt, Sandra Staley, Audris Huang, Richard Allen Nugent, Ke Chen, Sajiv K. Nair, James A. Nieman, Joseph Walter Strohbach
  • 4-oxo-1,4-dihydro-3-cinnolinecarboxamides as antiviral agents
    Patent number: 6624160
    Abstract: This invention provides compounds of formula I; which are useful as antiviral agents.
    Type: Grant
    Filed: March 15, 2001
    Date of Patent: September 23, 2003
    Assignee: Pharmacia & Upjohn Co.
    Inventors: Valerie A. Vaillancourt, Scott D. Larsen, Sajiv K. Nair
  • Pyrroloquinolones as antiviral agents
    Publication number: 20030153561
    Abstract: The present invention provides a compound of formula I 1
    Type: Application
    Filed: November 5, 2002
    Publication date: August 14, 2003
    Inventors: Valerie A. Vaillancourt, Sandra Staley, Audris Huang, Richard Allen Nugent, Ke Chen, Sajiv K. Nair, James A. Nieman, Joseph Walter Strohbach
  • Synthesis of epothilones
    Patent number: 6603015
    Abstract: Commercially feasible methods for synthesizing various epothilones precursors needed for the preparation of final epothilones are provided, including techniques for the synthesis of epothilone segment A and C precursors. Segment C precursors are prepared using starting nitriles, which can alternately be oxidized to ketones and converted, or reacted to form the diol with subsequent conversion to the segment. Segment A precursors are prepared by reacting a starting enone with a chiral catalyst to give an intermediate alcohol in high enantomeric excess, followed by conversion of the alcohol to the desired Segment A precursor.
    Type: Grant
    Filed: December 11, 2001
    Date of Patent: August 5, 2003
    Assignee: University of Kansas
    Inventors: Gunda I. Georg, Sajiv K. Nair, Emily Reiff, Ashok Rao Tunoori
  • Pyrroloquinolones as antiviral agents
    Patent number: 6525049
    Abstract: The present invention provides a compound of formula I which is useful as antiviral agents, in particular, as agents against viruses of the herpes family.
    Type: Grant
    Filed: June 22, 2001
    Date of Patent: February 25, 2003
    Assignee: Pharmacia & Upjohn Company
    Inventors: Valerie A. Vaillancourt, Sandra Staley, Audris Huang, Richard Allen Nugent, Ke Chen, Sajiv K. Nair, James A. Nieman, Joseph Walter Strohbach
  • SYNTHESIS OF EPOTHILONES
    Publication number: 20020165415
    Abstract: Commercially feasible methods for synthesizing various epothilones precursors needed for the preparation of final epothilones are provided, including techniques for the synthesis of epothilone segment C using a stereoselective Noyori-type reduction, and the coupling of epothilone segments B and C using an aldol condensation reaction. The synthesis methods may be used to prepare naturally occurring segments as well as a large number of related analogs and homologs thereof. Final epothilones in accordance with the invention may also be of the naturally occurring variety (16-membered macrolides), while the homologs and analogs thereof are preferably up to 20-membered macrolides.
    Type: Application
    Filed: March 2, 2001
    Publication date: November 7, 2002
    Inventors: Gunda I. Georg, Sajiv K. Nair, Emily Reiff, Ashok Rao Tunoori, John T. Henri
  • Synthesis of epothilones
    Publication number: 20020156289
    Abstract: Commercially feasible methods for synthesizing various epothilones precursors needed for the preparation of final epothilones are provided, including techniques for the synthesis of epothilone segment A and C precursors. Segment C precursors are prepared using starting nitriles, which can alternately be oxidized to ketones and converted, or reacted to form the diol with subsequent conversion to the segment. Segment A precursors are prepared by reacting a starting enone with a chiral catalyst to give an intermediate alcohol in high enantomeric excess, followed by conversion of the alcohol to the desired Segment A precursor.
    Type: Application
    Filed: December 11, 2001
    Publication date: October 24, 2002
    Applicant: THE UNIVERSITY OF KANSAS
    Inventors: Gunda I. Georg, Sajiv K. Nair, Emily Reiff, Ashok Rao Tunoori
  • 4-hydroxycinnoline-3-carboxyamides as antiviral agents
    Patent number: 6458788
    Abstract: Certain novel 4-hydroxycinnoline-3-carboxyamides. The compounds are particularly effective in the treatment or prevention of viral infections, particularly infections caused by herpes viruses including herpes simplex virus types 1 and 2, human herpes virus types 6, 7 and 8, varicello zoster virus, human cytomegalovirus or Epstein-Barr virus.
    Type: Grant
    Filed: March 15, 2001
    Date of Patent: October 1, 2002
    Assignee: Pharmacia & Upjohn Company
    Inventors: Valerie A. Vaillancourt, Scott D. Larsen, Sajiv K. Nair
  • Synthesis of epothilones
    Patent number: 6457303
    Abstract: Various epothilone precursors needed for the preparation of final epothilones are provided.
    Type: Grant
    Filed: March 2, 2001
    Date of Patent: October 1, 2002
    Assignee: The University of Kansas
    Inventors: Gunda I Georg, Sajiv K. Nair, Emily Reiff, Ashok Rao Tunoori, John T. Henri
  • Pyrroloquinolones as antiviral agents
    Publication number: 20020055636
    Abstract: The present invention provides a compound of formula I 1
    Type: Application
    Filed: June 22, 2001
    Publication date: May 9, 2002
    Inventors: Valerie A. Vaillancourt, Sandra Staley, Audris Huang, Richard Allen Nugent, Ke Chen, Sajiv K. Nair, James A. Nieman, Joseph W. Strohbach
  • 4-oxo-1,4-dihydro-3-cinnolinecarboxamides as antiviral agents
    Publication number: 20020045619
    Abstract: This invention provides compounds of formula I; 1
    Type: Application
    Filed: March 15, 2001
    Publication date: April 18, 2002
    Inventors: Valerie A. Vaillancourt, Scott D. Larsen, Sajiv K. Nair
  • 4-hydroxycinnoline-3-carboxyamides as antiviral agents
    Publication number: 20020042397
    Abstract: Certain novel 4-hydroxycinnoline-3-carboxyamides. The compounds are particularly effective in the treatment or prevention of viral infections, particularly infections caused by herpes viruses including herpes simplex virus types 1 and 2, human herpes virus types 6, 7 and 8, varicello zoster virus, human cytomegalovirus or Epstein-Barr virus.
    Type: Application
    Filed: March 15, 2001
    Publication date: April 11, 2002
    Inventors: Valerie A. Vaillancourt, Scott D. Larsen, Sajiv K. Nair
  • Synthesis of epothilones
    Patent number: 6211412
    Abstract: Commercially feasible methods for synthesizing various epothilones precursors needed for the preparation of final epothilones are provided, including techniques for the synthesis of epothilone segment C using a stereoselective Noyori-type reduction, and the coupling of epothilone segments B and C using an aldol condensation reaction. The synthesis methods may be used to prepare naturally occurring segments as well as a large number of related analogs and homologs thereof. Final epothilones in accordance with the invention may also be of the naturally occurring variety (16-membered macrolides), while the homologs and analogs thereof are preferably up to 20-membered macrolides.
    Type: Grant
    Filed: March 29, 1999
    Date of Patent: April 3, 2001
    Assignee: The University of Kansas
    Inventors: Gunda I. Georg, Sajiv K. Nair, Emily Reiff, Ashok Rao Tunoori, John T. Henri