Patents by Inventor Sally-Ann Cryan

Sally-Ann Cryan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR THE TREATMENT OF DISEASES BY ENHANCING ARGINASE 2 IN MACROPHAGES
    Publication number: 20230295634
    Abstract: Target site blockers and their use in enhancing Arginase 2 in macrophages to maintain macrophages in an anti-inflammatory and tissue repair phenotype are disclosed herein. Further disclosed are compositions and the use of the compositions for the treatment and/or prophylaxis of diseases mediated by macrophages such as inflammatory diseases, autoimmune diseases, neurological diseases or reparative diseases.
    Type: Application
    Filed: August 11, 2021
    Publication date: September 21, 2023
    Applicant: ROYAL COLLEGE OF SURGEONS IN IRELAND
    Inventors: Claire MCCOY, Chiara SANTI, Jennifer DOWLING, Sally-Ann CRYAN, Remsha AFZAL, Frances NALLY, Connor DUFFY
  • Star Polypeptides
    Publication number: 20220064378
    Abstract: A star polypeptide for use as a medicament, the star polypeptide comprising or consisting of a core and polypeptide arms radiating from the core. The star polypeptide may be used to deliver a therapeutic cargo and/or for its intrinsic properties. Therapeutic cargoes include a protein(e.g. VEGF); a nucleic acid (e.g. in vitro transcribed mRNA or microRNA); and/or a drug (e.g. diclofenac, azithromycin and/or rifampicin). Intrinsic properties include osteogenesis, angiogenesis and inhibition of bacteria.
    Type: Application
    Filed: December 23, 2019
    Publication date: March 3, 2022
    Inventors: Sally-Ann Cryan, Andreas Heise, David Walsh, Joanne O'Dwyer, Fergal O'Brien, Garry Duffy