Patents by Inventor Sally Rhiannon Postlethwaite

Sally Rhiannon Postlethwaite has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ?-Glucosidase variants
    Patent number: 8772010
    Abstract: The invention relates to recombinantly produced ?-Glucosidase Variants with enhanced thermoactivity compared to naturally occurring proteins. The invention also provides methods for producing a variant ?-glucosidase polypeptide with improved thermoactivity by identifying performance sensitive positions in a target ?-glucosidase polypeptide and substituting the residue at that position with a thermoactivity enhancing residue.
    Type: Grant
    Filed: June 16, 2010
    Date of Patent: July 8, 2014
    Assignee: Codexis, Inc.
    Inventors: Xiyun Zhang, Jie Yang, Dipnath Baidyaroy, Sally Rhiannon Postlethwaite, Attila Andor, Louis Clark, Lisa M. Newman
  • Method for producing an alcohol using ?-glucosidase variant enzymes
    Patent number: 8715975
    Abstract: The invention provides variants of the Azospirillum irakense CelA ?-glucosidase that have improve ?-glucosidase activity, particularly improved thermoactivity, compared to the wild type enzyme. The invention further provides related polynucleotides, vectors, host cell, and methods for making and using the variants.
    Type: Grant
    Filed: September 5, 2013
    Date of Patent: May 6, 2014
    Assignee: Codexis, Inc.
    Inventors: Sally Rhiannon Postlethwaite, Louis Clark, Catherine M. Cho
  • BETA-GLUCOSIDASE VARIANT ENZYMES AND RELATED POLYNUCLEOTIDES
    Publication number: 20140004586
    Abstract: The invention provides variants of the Azospirillum irakense CelA ?-glucosidase that have improve ?-glucosidase activity, particularly improved thermoactivity, compared to the wild type enzyme. The invention further provides related polynucleotides, vectors, host cell, and methods for making and using the variants.
    Type: Application
    Filed: September 5, 2013
    Publication date: January 2, 2014
    Applicant: Codexis, Inc.
    Inventors: Sally Rhiannon Postlethwaite, Louis Clark, Catherine M. Cho
  • Method of converting a biomass substrate to a fermentable sugar using a beta-glucosidase variant enzyme
    Patent number: 8530201
    Abstract: The invention provides variants of the Azospirillum irakense CelA ?-glucosidase that have improve ?-glucosidase activity, particularly improved thermoactivity, compared to the wild type enzyme. The invention further provides related polynucleotides, vectors, host cell, and methods for making and using the variants.
    Type: Grant
    Filed: December 19, 2012
    Date of Patent: September 10, 2013
    Assignee: Codexis, Inc.
    Inventors: Sally Rhiannon Postlethwaite, Louis Clark, Catherine M. Cho
  • Beta-glucosidase variant enzymes and related polynucleotides
    Patent number: 8357523
    Abstract: The invention provides variants of the Azospirillum irakense CelA ?-glucosidase that have improve ?-glucosidase activity, particularly improved thermoactivity, compared to the wild type enzyme. The invention further provides related polynucleotides, vectors, host cell, and methods for making and using the variants.
    Type: Grant
    Filed: June 16, 2010
    Date of Patent: January 22, 2013
    Assignee: Codexis, Inc.
    Inventors: Sally Rhiannon Postlethwaite, Louis Clark, Catherine M. Cho
  • Beta-Glucosidase Variants
    Publication number: 20120077216
    Abstract: The invention relates to recombinantly produced ?-Glucosidase Variants with enhanced thermoactivity compared to naturally occurring proteins. The invention also provides methods for producing a variant ?-glucosidase polypeptide with improved thermoactivity by identifying performance sensitive positions in a target ?-glucosidase polypeptide and substituting the residue at that position with a thermoactivity enhancing residue.
    Type: Application
    Filed: June 16, 2010
    Publication date: March 29, 2012
    Applicant: Codexis, Inc.
    Inventors: Xiyun Zhang, Jie Yang, Dipnath Baidyaroy, Sally Rhiannon Postlethwaite, Attila Andor, Louis Clark, Lisa M. Newman
  • BETA-GLUCOSIDASE VARIANT ENZYMES AND RELATED POLYNUCLEOTIDES
    Publication number: 20100317059
    Abstract: The invention provides variants of the Azospirillum irakense CelA ?-glucosidase that have improve ?-glucosidase activity, particularly improved thermoactivity, compared to the wild type enzyme. The invention further provides related polynucleotides, vectors, host cell, and methods for making and using the variants.
    Type: Application
    Filed: June 16, 2010
    Publication date: December 16, 2010
    Applicant: CODEXIS, INC.
    Inventors: Sally Rhiannon Postlethwaite, Louis Clark