Patents by Inventor Salvador Marquez
Salvador Marquez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230414359Abstract: A testing apparatus is disclosed herein for testing properties of a prosthetic device. The testing apparatus may comprise a dual-drive pulsatile flow tester with the ability to determine coaptation of valve leaflets of a prosthetic device. The testing apparatus may be able to test prosthetic heart valves and reproduce physiological conditions of a prosthetic heart valve.Type: ApplicationFiled: September 12, 2023Publication date: December 28, 2023Inventors: Salvador Marquez, Lynn T. Dang, Javier A. Sanguinetti, Emily Cheng Zhou, Gary Alan Breitbach
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Patent number: 11786374Abstract: A testing apparatus is disclosed herein for testing properties of a prosthetic device. The testing apparatus may comprise a dual-drive pulsatile flow tester with the ability to determine coaptation of valve leaflets of a prosthetic device. The testing apparatus may be able to test prosthetic heart valves and reproduce physiological conditions of a prosthetic heart valve.Type: GrantFiled: January 22, 2021Date of Patent: October 17, 2023Assignee: EDWARDS LIFESCIENCES CORPORATIONInventors: Salvador Marquez, Lynn T. Dang, Javier A. Sanguinetti, Emily Cheng Zhou, Gary Alan Breitbach
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Publication number: 20230125047Abstract: A minimally-invasive annuloplasty ring for implant at a mitral annulus. The annuloplasty ring has an inner core member with a C-shaped plan view that generally defines an oval with a major axis and a minor axis, and is symmetric about the minor axis. A posterior portion of the core member bisected by the minor axis has a thicker radial dimension than a pair of free end regions terminating on an anterior side of the core member. The radial thickness smoothly transitions between the posterior portion and the end regions. The inner core member may be covered with a fabric, and is a superelastic metal so that it can be straightened out and delivered through an access tube. The curvatures and thicknesses around the core member are selected so that the strain experienced when straightened does not exceed 7-8%.Type: ApplicationFiled: December 20, 2022Publication date: April 20, 2023Inventors: Brian S. Conklin, Louis A. Campbell, Salvador Marquez, James R. Yamada, Rodolfo Rodriguez, Da-Yu Chang, Steven M. Ford
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Publication number: 20230068893Abstract: Sensor-integrated prosthetic valves that can comprise a variety of features, including a plurality of valve leaflets, a frame assembly configured to support the plurality of valve leaflets and define a plurality of commissure supports terminating at an outflow end of the prosthetic valve, a sensor device associated with the frame assembly and configured to generate a sensor signal, for example, a sensor signal indicating deflection of one or more of the plurality of commissure supports, and a transmitter assembly configured to receive the sensor signal from the sensor device and wirelessly transmit a transmission signal that is based at least in part on the sensor signal.Type: ApplicationFiled: October 13, 2022Publication date: March 2, 2023Inventors: Salvador Marquez, Da-Yu Chang, Cindy Woo, Hao-Chung Yang, Lynn T. Dang, Javier A. Sanguinetti, Alexander H. Siemons, Yaron Keidar, Virginia Qi Lin, Brian S. Conklin, Donald E. Bobo, Jr.
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Patent number: 11576667Abstract: Suture locking clamps for securing prostheses such as heart valves or annuloplasty rings with sutures and without using knots improve the ease of implantation. The clamps have opposed clamp halves separated by a slot opening to one side and surrounded by a biasing member such as one or more C-clip springs. Sutures pass laterally into the slot which is held open by a retention member positioned between the clamp halves. The locking clamp slides along the sutures into position, the tension of the sutures is adjusted, and the retention member removed to allow the biasing member to clamp the sutures between the clamp halves. A delivery tool used to deliver and deploy the locking clamps contains a number of clamps within a delivery tube in a stack and bonded together for safety and a common retention member. The tool has a longitudinal channel on one side for entry of sutures.Type: GrantFiled: April 27, 2020Date of Patent: February 14, 2023Assignee: Edwards Lifesciences CorporationInventors: Brian S. Conklin, Louis A. Campbell, Salvador Marquez, Donald E. Bobo, Jr.
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Patent number: 11554015Abstract: A minimally-invasive annuloplasty ring for implant at a mitral annulus. The annuloplasty ring has an inner core member with a C-shaped plan view that generally defines an oval with a major axis and a minor axis, and is symmetric about the minor axis. A posterior portion of the core member bisected by the minor axis has a thicker radial dimension than a pair of free end regions terminating on an anterior side of the core member. The radial thickness smoothly transitions between the posterior portion and the end regions. The inner core member may be covered with a fabric, and is a superelastic metal so that it can be straightened out and delivered through an access tube. The curvatures and thicknesses around the core member are selected so that the strain experienced when straightened does not exceed 7-8%.Type: GrantFiled: January 27, 2021Date of Patent: January 17, 2023Assignee: Edwards Lifesciences CorporationInventors: Brian S. Conklin, Louis A. Campbell, Salvador Marquez, James R. Yamada, Rodolfo Rodriguez, Da-Yu Chang, Steven M. Ford
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Patent number: 11471275Abstract: Sensor-integrated prosthetic valves that can comprise a variety of features, including a plurality of valve leaflets, a frame assembly configured to support the plurality of valve leaflets and define a plurality of commissure supports terminating at an outflow end of the prosthetic valve, a sensor device associated with the frame assembly and configured to generate a sensor signal, for example, a sensor signal indicating deflection of one or more of the plurality of commissure supports, and a transmitter assembly configured to receive the sensor signal from the sensor device and wirelessly transmit a transmission signal that is based at least in part on the sensor signal.Type: GrantFiled: May 29, 2020Date of Patent: October 18, 2022Assignee: Edwards Lifesciences CorporationInventors: Salvador Marquez, Da-Yu Chang, Cindy Woo, Hao-Chung Yang, Lynn T. Dang, Javier A. Sanguinetti, Alexander H. Siemons, Yaron Keidar, Virginia Qi Lin, Brian S. Conklin, Donald E. Bobo, Jr.
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Patent number: 11464633Abstract: A cardiac implant system including a cardiac implant such as an annuloplasty ring, a prosthetic heart valve, or a valved conduit pre-assembled at the time of manufacture with devices for securing the implant to a heart valve annulus using knotless suture fasteners. The knotless suture fasteners may be embedded within a pliant sealing edge of the cardiac implant, or they may be positioned adjacent to the sealing edge. The knotless suture fasteners are spring-biased so as to grip onto annulus anchoring sutures pass to therethrough upon removal of a restraining device, such as a hypotube inserted within the suture fasteners. Guide tubes are assembled in line with the suture fasteners to permit introduction of suture snares that pass through the suture fasteners and through the sealing edge to facilitate capture of the pre-installed annulus anchoring sutures.Type: GrantFiled: June 10, 2019Date of Patent: October 11, 2022Assignee: Edwards Lifesciences CorporationInventors: Salvador Marquez, Brian S. Conklin, Manouchehr A. Miraki, Yoon Hee Kwon
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Publication number: 20210145581Abstract: A minimally-invasive annuloplasty ring for implant at a mitral annulus. The annuloplasty ring has an inner core member with a C-shaped plan view that generally defines an oval with a major axis and a minor axis, and is symmetric about the minor axis. A posterior portion of the core member bisected by the minor axis has a thicker radial dimension than a pair of free end regions terminating on an anterior side of the core member. The radial thickness smoothly transitions between the posterior portion and the end regions. The inner core member may be covered with a fabric, and is a superelastic metal so that it can be straightened out and delivered through an access tube. The curvatures and thicknesses around the core member are selected so that the strain experienced when straightened does not exceed 7-8%.Type: ApplicationFiled: January 27, 2021Publication date: May 20, 2021Inventors: Brian S. Conklin, Louis A. Campbell, Salvador Marquez, James R. Yamada, Rodolfo Rodriguez, Da-Yu Chang, Steven M. Ford
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Publication number: 20210137682Abstract: A testing apparatus is disclosed herein for testing properties of a prosthetic device. The testing apparatus may comprise a dual-drive pulsatile flow tester with the ability to determine coaptation of valve leaflets of a prosthetic device. The testing apparatus may be able to test prosthetic heart valves and reproduce physiological conditions of a prosthetic heart valve.Type: ApplicationFiled: January 22, 2021Publication date: May 13, 2021Inventors: Salvador Marquez, Lynn T. Dang, Javier A. Sanguinetti, Emily Cheng Zhou, Gary Alan Breitbach
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Patent number: 10898329Abstract: A testing apparatus is disclosed herein for testing properties of a prosthetic device. The testing apparatus may comprise a dual-drive pulsatile flow tester with the ability to determine coaptation of valve leaflets of a prosthetic device. The testing apparatus may be able to test prosthetic heart valves and reproduce physiological conditions of a prosthetic heart valve.Type: GrantFiled: January 25, 2019Date of Patent: January 26, 2021Assignee: Edwards Lifesciences CorporationInventors: Salvador Marquez, Lynn T. Dang, Javier A. Sanguinetti, Emily Cheng Zhou, Gary Alan Breitbach
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Publication number: 20200289257Abstract: Sensor-integrated prosthetic valves that can comprise a variety of features, including a plurality of valve leaflets, a frame assembly configured to support the plurality of valve leaflets and define a plurality of commissure supports terminating at an outflow end of the prosthetic valve, a sensor device associated with the frame assembly and configured to generate a sensor signal, for example, a sensor signal indicating deflection of one or more of the plurality of commissure supports, and a transmitter assembly configured to receive the sensor signal from the sensor device and wirelessly transmit a transmission signal that is based at least in part on the sensor signal.Type: ApplicationFiled: May 29, 2020Publication date: September 17, 2020Inventors: Salvador Marquez, Da-Yu Chang, Cindy Woo, Hao-Chung Yang, Lynn T. Dang, Javier A. Sanguinetti, Alexander H. Siemons, Yaron Keidar, Virginia Qi Lin, Brian S. Conklin, Donald E. Bobo, JR.
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Publication number: 20200253601Abstract: Suture locking clamps for securing prostheses such as heart valves or annuloplasty rings with sutures and without using knots improve the ease of implantation. The clamps have opposed clamp halves separated by a slot opening to one side and surrounded by a biasing member such as one or more C-clip springs. Sutures pass laterally into the slot which is held open by a retention member positioned between the clamp halves. The locking clamp slides along the sutures into position, the tension of the sutures is adjusted, and the retention member removed to allow the biasing member to clamp the sutures between the clamp halves. A delivery tool used to deliver and deploy the locking clamps contains a number of clamps within a delivery tube in a stack and bonded together for safety and a common retention member. The tool has a longitudinal channel on one side for entry of sutures.Type: ApplicationFiled: April 27, 2020Publication date: August 13, 2020Inventors: Brian S. Conklin, Louis A. Campbell, Salvador Marquez, Donakj E. Bobo, JR.
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Publication number: 20200237515Abstract: A testing apparatus is disclosed herein for testing properties of a prosthetic device. The testing apparatus may comprise a dual-drive pulsatile flow tester with the ability to determine coaptation of valve leaflets of a prosthetic device. The testing apparatus may be able to test prosthetic heart valves and reproduce physiological conditions of a prosthetic heart valve.Type: ApplicationFiled: January 25, 2019Publication date: July 30, 2020Inventors: Salvador Marquez, Lynn T. Dang, Javier A. Sanguinetti, Emily Cheng Zhou, Gary Alan Breitbach
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Patent number: 10667904Abstract: Sensor-integrated prosthetic valves that can comprise a variety of features, including a plurality of valve leaflets, a frame assembly configured to support the plurality of valve leaflets and define a plurality of commissure supports terminating at an outflow end of the prosthetic valve, a sensor device associated with the frame assembly and configured to generate a sensor signal, for example, a sensor signal indicating deflection of one or more of the plurality of commissure supports, and a transmitter assembly configured to receive the sensor signal from the sensor device and wirelessly transmit a transmission signal that is based at least in part on the sensor signal.Type: GrantFiled: March 7, 2017Date of Patent: June 2, 2020Assignee: Edwards Lifesciences CorporationInventors: Salvador Marquez, Da-Yu Chang, Cindy Woo, Hao-Chung Yang, Lynn T. Dang, Javier A. Sanguinetti, Alexander H. Siemons, Yaron Keidar, Virginia Qi Lin, Brian S. Conklin, Donald E. Bobo, Jr.
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Patent number: 10631854Abstract: Suture locking clamps for securing prostheses such as heart valves or annuloplasty rings with sutures and without using knots improve the ease of implantation. The clamps have opposed clamp halves separated by a slot opening to one side and surrounded by a biasing member such as one or more C-clip springs. Sutures pass laterally into the slot which is held open by a retention member positioned between the clamp halves. The locking clamp slides along the sutures into position, the tension of the sutures is adjusted, and the retention member removed to allow the biasing member to clamp the sutures between the clamp halves. A delivery tool used to deliver and deploy the locking clamps contains a number of clamps within a delivery tube in a stack and bonded together for safety and a common retention member. The tool has a longitudinal channel on one side for entry of sutures.Type: GrantFiled: April 3, 2018Date of Patent: April 28, 2020Assignee: Edwards Lifesciences CorporationInventors: Brian S. Conklin, Louis A. Campbell, Salvador Marquez, Donald E. Bobo, Jr.
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Publication number: 20190290428Abstract: A cardiac implant system including a cardiac implant such as an annuloplasty ring, a prosthetic heart valve, or a valved conduit pre-assembled at the time of manufacture with devices for securing the implant to a heart valve annulus using knotless suture fasteners. The knotless suture fasteners may be embedded within a pliant sealing edge of the cardiac implant, or they may be positioned adjacent to the sealing edge. The knotless suture fasteners are spring-biased so as to grip onto annulus anchoring sutures pass to therethrough upon removal of a restraining device, such as a hypotube inserted within the suture fasteners. Guide tubes are assembled in line with the suture fasteners to permit introduction of suture snares that pass through the suture fasteners and through the sealing edge to facilitate capture of the pre-installed annulus anchoring sutures.Type: ApplicationFiled: June 10, 2019Publication date: September 26, 2019Inventors: Salvador Marquez, Brian S. Conklin, Manouchehr A. Miraki, Yoon Hee Kwon
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Patent number: 10314706Abstract: A cardiac implant system including a cardiac implant such as an annuloplasty ring, a prosthetic heart valve, or a valved conduit pre-assembled at the time of manufacture with devices for securing the implant to a heart valve annulus using knotless suture fasteners. The knotless suture fasteners may be embedded within a pliant sealing edge of the cardiac implant, or they may be positioned adjacent to the sealing edge. The knotless suture fasteners are spring-biased so as to grip onto annulus anchoring sutures pass to therethrough upon removal of a restraining device, such as a hypotube inserted within the suture fasteners. Guide tubes are assembled in line with the suture fasteners to permit introduction of suture snares that pass through the suture fasteners and through the sealing edge to facilitate capture of the pre-installed annulus anchoring sutures.Type: GrantFiled: June 16, 2017Date of Patent: June 11, 2019Assignee: Edwards Lifesciences CorporationInventors: Salvador Marquez, Brian S. Conklin, Manouchehr A. Miraki, Yoon H. Kwon
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Publication number: 20180221016Abstract: Suture locking clamps for securing prostheses such as heart valves or annuloplasty rings with sutures and without using knots improve the ease of implantation. The clamps have opposed clamp halves separated by a slot opening to one side and surrounded by a biasing member such as one or more C-clip springs. Sutures pass laterally into the slot which is held open by a retention member positioned between the clamp halves. The locking clamp slides along the sutures into position, the tension of the sutures is adjusted, and the retention member removed to allow the biasing member to clamp the sutures between the clamp halves. A delivery tool used to deliver and deploy the locking clamps contains a number of clamps within a delivery tube in a stack and bonded together for safety and a common retention member. The tool has a longitudinal channel on one side for entry of sutures.Type: ApplicationFiled: April 3, 2018Publication date: August 9, 2018Inventors: Brian S. Conklin, Louis A. Campbell, Salvador Marquez, Donald E. Bobo, Jr.
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Patent number: 9968451Abstract: A cardiac implant system including a cardiac implant such as an annuloplasty ring, a prosthetic heart valve, or a valved conduit pre-assembled at the time of manufacture with devices for securing the implant to a heart valve annulus using knotless suture fasteners. The knotless suture fasteners may be embedded within a pliant sealing edge of the cardiac implant, or they may be positioned adjacent to the sealing edge. The knotless suture fasteners are spring-biased so as to grip onto annulus anchoring sutures pass to therethrough upon removal of a restraining device, such as a hypotube inserted within the suture fasteners. Guide tubes are assembled in line with the suture fasteners to permit introduction of suture snares that pass through the suture fasteners and through the sealing edge to facilitate capture of the pre-installed annulus anchoring sutures.Type: GrantFiled: October 17, 2016Date of Patent: May 15, 2018Assignee: Edwards Lifesciences CorporationInventors: Salvador Marquez, Brian S. Conklin, Manouchehr A. Miraki, Yoon H. Kwon