Abstract: The development of perspiration is inhibited by topical application of 3-phenyl-3-carbo-(beta-di-lower alkylamino)-lower alkoxy-2,3-dihydrobenzofuran or a salt thereof, preferably the hydrochloride, and an antiperspirant aluminum, zinc, or zirconium salt, preferably aluminum chlorohydrate or aluminum chloride. The compositions applied may be aqueous, preferably including a surface active agent, such as a nonionic synthetic surface active compound of poly-lower alkylene oxide, or they may be non-aqueous, as in "aerosol" powder sprays. The amounts of the composition employed are small and the proportion of antiperspirant metal salt present is greater than that of the dihydrobenzofuran compound.

Abstract: A method for inhibiting perspiration comprises applying to a site at which perspiration is normally exuded, an antiperspirant of the formula ##SPC1##Or a salt thereof. In preferred compounds, A, B, D, E, and G are hydrogen and R is phenyl, alkyl, hydroxyalkyl, aminoalkyl, alkenyl or oxopyridyl. Also useful are the corresponding hydrohalic acid salts. The compounds are preferably applied to the human axillae as aqueous antiperspirant compositions containing a surface active agent. Some of the S-substituted benzothiohydroximic acids and hydrohalic acid salts are new compounds of especially good antiperspirant activities, e.g., those in which the R group is linear alkyl of 6 to 9 carbon atoms, lower aminoalkyl, lower hydroxyalkyl, 1-oxopyridyl, and the hydrochloric acid salts of the compounds in which R is lower aminoalkyl.