Patents by Inventor Sam Pellock

Sam Pellock has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • De novo designed NTF2-like scaffolds for de novo design of enzymes and small molecule binders
    Publication number: 20230295639
    Abstract: Polypeptide are disclosed that comprise an amino acid sequence at least 35%, 40%, 45%, 50%, 55%, 60%, 65%, 70%, 75%, 80%, 85%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to the amino acid sequence selected from the group consisting of SEQ ID NO:1-1615, not including any functional domains added fused to the protein (whether N-terminal, C-terminal, or internal), and wherein the 1, 2, 3, 4, or 5 N-terminal and/or C-terminal amino acid residues may be present or absent when considering the percent identity.
    Type: Application
    Filed: January 17, 2023
    Publication date: September 21, 2023
    Inventors: Christoffer NORN, Ivan ANISHCHANKA, David BAKER, Sam PELLOCK, Douglas TISCHER, Hsien-Wei YEH
  • Inhibitors of microbial beta-glucuronidase enzymes and uses thereof
    Patent number: 11339178
    Abstract: Compounds and compositions are provided that comprise selective b-glucuronidase inhibitors. The compounds and compositions can ameliorate the side effects of chemotherapeutic agents and can improve the efficacy of such agents, including irinotecan and non-steroidal anti-inflammatory drugs.
    Type: Grant
    Filed: July 20, 2017
    Date of Patent: May 24, 2022
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Matthew R. Redinbo, Jian Jin, Lindsey James, Sam Pellock, Ranathunga Arachchillage Yamuna Ariyarathna, Stephen Frye
  • INHIBITORS OF MICROBIAL BETA-GLUCURONIDASE ENZYMES AND USES THEREOF
    Publication number: 20190330237
    Abstract: Compounds and compositions are provided that comprise selective b-glucuronidase inhibitors. The compounds and compositions can ameliorate the side effects of chemotherapeutic agents and can improve the efficacy of such agents, including irinotecan and non-steroidal anti-inflammatory drugs.
    Type: Application
    Filed: July 20, 2017
    Publication date: October 31, 2019
    Applicant: The University of North Carolina at Chapel Hill
    Inventors: Matthew R. Redinbo, Jian Jin, Lindsey James, Sam Pellock, Ranathunga Arachchillage Yamu Ariyarathna, Stephen Frye