Abstract: A method and system of providing customer-specific information and guidance to insurance policyholders during claims processing. The information is created based on outputs from a claims complexity model, customer segmentation model, and claims service level objective (SLO) model. The resulting information is tailored to the individual policyholder and their claim, and includes a summary of their claim activity, guidance regarding their next steps, and predicted wait times for each stage in their claim's processing. In some embodiments, the information is presented as messaging delivered over the policyholder's preferred communication channel(s) that can differ based on which stage of the claims process the claim is in.

Abstract: A packaging device for a trocar assembly includes a trocar packaging clip having at least two holding structures configured to be detachably secured to the proximal portions of the trocar obturator and the cannula for retention of the trocar obturator and cannula relative to each other. The trocar packaging clip includes an anti-rotation structure configured to engage at least one of the trocar and the cannula to prevent relative rotation thereof.

Abstract: The disclosure pertains to a recombinant adeno-associated virus (rAAV) comprising an Anc80L65 capsid for delivering a polynucleotide (e.g., a transgene) into the central nervous system (CNS). Further provided includes methods for treating CNS diseases using the rAAV and pharmaceutical compositions comprising the rAAV.

Abstract: A packaging device for a trocar assembly includes a trocar packaging clip having at least two holding structures configured to be detachably secured to the proximal portions of the trocar obturator and the cannula for retention of the trocar obturator and cannula relative to each other.

Abstract: A packaging device for a trocar assembly includes a trocar packaging clip having at least two holding structures configured to be detachably secured to the proximal portions of the trocar obturator and the cannula for retention of the trocar obturator and cannula relative to each other. The trocar packaging clip includes an anti-rotation structure configured to engage at least one of the trocar and the cannula to prevent relative rotation thereof.

Abstract: An ultrafast electromechanical switch having a drive mechanism comprising two non-movable contacts connected to electrical feedthroughs, one actuator and one movable contact. The provided ultrafast electrical (e.g., transfer, disconnect, etc.) switch is simple, compact, clean, exhibits ultralow loss, does not require high energy to operate and is capable of being automatically reset.

Abstract: An ultrafast electromechanical switch having a drive mechanism comprising three non-movable contacts, an actuator and two movable contacts. The switch further including a switching chamber to provide a self-contained environment that may consist of a high-pressure gas or a vacuum and one or more precision adjustment screws coupled to the non-movable contacts for adjusting the contact pressure. The provided ultrafast electrical (e.g., transfer, disconnect, etc.) switch is simple, compact, clean, exhibits ultralow loss, does not require high energy to operate and is capable of being automatically reset.

Abstract: An ultrafast electromechanical switch having a drive mechanism comprising three non-movable contacts, an actuator and two movable contacts. The switch further including one or more precision adjustment screws coupled to the non-movable contacts for adjusting the contact pressure. The provided ultrafast electrical (e.g., transfer, disconnect, etc.) switch is simple, compact, clean, exhibits ultralow loss, does not require high energy to operate and is capable of being automatically reset.

Abstract: An ultrafast electromechanical switch having a drive mechanism comprising three non-movable contacts, an actuator, two movable contacts and a first and second mounting plate forming an elliptical shell configuration about said actuator. The switch further including a switching chamber to provide a self-contained environment that may consist of a high-pressure gas or a vacuum and one or more precision adjustment screws coupled to the non-movable contacts for adjusting the contact pressure. The provided ultrafast electrical (e.g., transfer, disconnect, etc.) switch is simple, compact, clean, exhibits ultralow loss, does not require high energy to operate and is capable of being automatically reset.

Abstract: An ultrafast electromechanical switch having a drive mechanism comprising three non-movable contacts, an actuator and two movable contacts. The switch further including one or more precision adjustment screws coupled to the non-movable contacts for adjusting the contact pressure. The provided ultrafast electrical (e.g., transfer, disconnect, etc.) switch is simple, compact, clean, exhibits ultralow loss, does not require high energy to operate and is capable of being automatically reset.

Abstract: An ultrafast electromechanical switch having a drive mechanism comprising two non-movable contacts connected to electrical feedthroughs, one actuator and one movable contact. The provided ultrafast electrical (e.g., transfer, disconnect, etc.) switch is simple, compact, clean, exhibits ultralow loss, does not require high energy to operate and is capable of being automatically reset.

Abstract: An ultrafast electromechanical switch having a drive mechanism comprising three non-movable contacts, an actuator, two movable contacts and a first and second mounting plate forming an elliptical shell configuration about said actuator. The switch further including a switching chamber to provide a self-contained environment that may consist of a high-pressure gas or a vacuum and one or more precision adjustment screws coupled to the non-movable contacts for adjusting the contact pressure. The provided ultrafast electrical (e.g., transfer, disconnect, etc.) switch is simple, compact, clean, exhibits ultralow loss, does not require high energy to operate and is capable of being automatically reset.

Abstract: An ultrafast electromechanical switch having a drive mechanism comprising three non-movable contacts, an actuator and two movable contacts. The switch further including a switching chamber to provide a self-contained environment that may consist of a high-pressure gas or a vacuum and one or more precision adjustment screws coupled to the non-movable contacts for adjusting the contact pressure. The provided ultrafast electrical (e.g., transfer, disconnect, etc.) switch is simple, compact, clean, exhibits ultralow loss, does not require high energy to operate and is capable of being automatically reset.

Abstract: An ultrafast electrical (e.g., transfer, disconnect, etc.) switch that is simple, compact, does not require high energy to operate, ultralow loss, clean, and capable of being automatically reset. The invention includes a fast electromechanical switch having a drive mechanism integrated into the switching chamber. The integration of the drive mechanism into the switching chamber provides faster contact travel and therefore a faster switching operation. Additionally, the switching chamber is a self-contained environment that may consist of a high-pressure gas or a vacuum. The invention further includes an ultrafast disconnect switch. The invention generally is an integrated piezoelectric-actuator-based mechanical switching mechanism. The mechanism has a central piezoelectric actuator that extends to pull contacts inwards in order to obtain two disconnects within a millisecond or less. Surrounding the piezoelectric actuator is a polymer insulating shell and beyond the shell is the metallic conductor.

Abstract: The present application discloses novel amino-sulfide metal catalysts for organic chemical syntheses including hydrogenation (reduction) of unsaturated compounds or dehydrogenation of substrates. The range of hydrogenation substrate compounds includes esters, lactones, oils and fats, resulting in alcohols, diols, and triols as reaction products. The catalysts of current application can be used to catalyze a hydrogenation reaction under solvent free conditions. The present catalysts also allow the hydrogenation to proceed without added base, and it can be used in place of the conventional reduction methods employing hydrides of the main-group elements. Furthermore, the catalysts of the present application can catalyze a dehydrogenation reaction under homogenous and/or acceptorless conditions. As such, the catalysts provided herein can be useful in substantially reducing cost and improving the environmental profile of manufacturing processes for a variety of chemicals.

Abstract: The present application discloses novel amino-sulfide metal catalysts for organic chemical syntheses including hydrogenation (reduction) of unsaturated compounds or dehydrogenation of substrates. The range of hydrogenation substrate compounds includes esters, lactones, oils and fats, resulting in alcohols, diols, and triols as reaction products. The catalysts of current application can be used to catalyze a hydrogenation reaction under solvent free conditions. The present catalysts also allow the hydrogenation to proceed without added base, and it can be used in place of the conventional reduction methods employing hydrides of the main-group elements. Furthermore, the catalysts of the present application can catalyze a dehydrogenation reaction under homogenous and/or acceptorless conditions. As such, the catalysts provided herein can be useful in substantially reducing cost and improving the environmental profile of manufacturing processes for a variety of chemicals.

Abstract: An ultrafast electrical (e.g., transfer, disconnect, etc.) switch that is simple, compact, does not require high energy to operate, ultralow loss, clean, and capable of being automatically reset. The invention includes a fast electromechanical switch having a drive mechanism integrated into the switching chamber. The integration of the drive mechanism into the switching chamber provides faster contact travel and therefore a faster switching operation. Additionally, the switching chamber is a self-contained environment that may consist of a high-pressure gas or a vacuum. The invention further includes an ultrafast disconnect switch. The invention generally is an integrated piezoelectric-actuator-based mechanical switching mechanism. The mechanism has a central piezoelectric actuator that extends to pull contacts inwards in order to obtain two disconnects within a millisecond or less. Surrounding the piezoelectric actuator is a polymer insulating shell and beyond the shell is the metallic conductor.

Abstract: A packaging device for a trocar assembly includes a trocar packaging clip having at least two holding structures configured to be detachably secured to the proximal portions of the trocar obturator and the cannula for retention of the trocar obturator and cannula relative to each other. The trocar packaging clip includes an anti-rotation structure configured to engage at least one of the trocar and the cannula to prevent relative rotation thereof.

Abstract: The present application discloses novel amino-sulfide metal catalysts for organic chemical syntheses including hydrogenation (reduction) of unsaturated compounds or dehydrogenation of substrates. The range of hydrogenation substrate compounds includes esters, lactones, oils and fats, resulting in alcohols, diols, and triols as reaction products. The catalysts of current application can be used to catalyze a hydrogenation reaction under solvent free conditions. The present catalysts also allow the hydrogenation to proceed without added base, and it can be used in place of the conventional reduction methods employing hydrides of the main-group elements. Furthermore, the catalysts of the present application can catalyze a dehydrogenation reaction under homogenous and/or acceptorless conditions. As such, the catalysts provided herein can be useful in substantially reducing cost and improving the environmental profile of manufacturing processes for a variety of chemicals.

Abstract: A hair transformation agent, useful in transforming hair texture from kinky to curly, by application of this non permanent solution. The solution acts like the sebum of a human. Hair that is naturally rich in sebum is healthy, shiny, strong, nourished. Hair that is lacking is in typically in bad condition. Hair shaft can lack sebum because of chemical use, but seems to be a natural occurrence in kinky hair. Because of this people with kinky hair often seek extreme measures to restore their hair or make it more manageable. Most resort to chemical processing to change the texture look and feel of the hair only this just makes the hair worst. Our formula will give kinky hair the sebum it is lacking and in the process the hair will begin to act, look and feel like another hair texture that has abundant sebum naturally, curly hair, and textural change will occur.