Abstract: Vascular prosthesis includes a luminal graft component defining a graft fenestration, at least one support disk fenestration, and a moveable disk defining a moveable disk opening, wherein the graft fenestration, the support disk fenestration and the moveable disk opening are all aligned, and the moveable disk is sandwiched between the support disk and the luminal graft component or between two of the support disks. The moveable disk is moveable between the support disk and the luminal graft component. The support disk is fixed to the luminal graft component. The vascular prosthesis is implanted by a method that includes directing the vascular prosthesis to an aneurysm site of a patient, and then implanting a branch prosthesis through the graft fenestration and into an arterial branch, whereby the moveable disk opening moves within the support disk fenestration to properly align the branch prosthesis with the arterial branch.

Abstract: Methods for delivering a vascular prosthesis to a treatment site of a subject include advancing the vascular prosthesis, rotating a proximal handle in a first direction about a handle body, shifting the position of a first locking component securing the proximal handle to the push rod from a first position to a second position, rotating the proximal handle in a second direction, releasing the proximal end of the prosthesis from the apex delivery device, shifting the second locking component to disengage the push rod from the handle body; and withdrawing the push rod and the guidewire catheter from within the prosthesis, thereby delivering the vascular prosthesis to the treatment site.

Abstract: A stent graft for treating an arterial aneurysm includes loops fixed to struts of stents, wherein the struts define distal and proximal apices. The ends of a ligature can be linked by a wire in a stent graft delivery system that threads anchor loops longitudinally spanning ends of the ligature to maintain the stent in a radially constricted position during delivery to the aneurysm. A delivery system and method for implanting a stent graft prosthesis includes and employs a torque component at a distal end of the stent graft prosthesis, whereby following advancement of the stent graft to a surgical site in a constrained or partially constrained configuration, torque is applied to the torque component to rotationally align the stent graft about a longitudinal axis of the stent graft, followed by deployment of the stent graft in correct rotational alignment.

Abstract: A stent graft delivery system and method for implanting a stent graft includes and employs at least one control rod that extends along a luminal wall of a stent graft and at least one ligature. The ligature extends about radial stents. Rotation of the control rod or a tube extending about the control rod wraps the ligature about the control rod, thereby radial constricting the stent about which the ligature extends.

Abstract: A stent graft delivery system and method for implanting a stent graft includes and employs at least one control rod that extends along a luminal wall of a stent graft and at least one ligature. The ligature extends about radial stents. Rotation of the control rod or a tube extending about the control rod wraps the ligature about the control rod, thereby radial constricting the stent about which the ligature extends.

Abstract: A stent graft delivery device includes a handle body, a distal handle, a proximal handle, a guidewire lumen, a nose cone, a rigid outer catheter, a graft push lumen, a sheath lumen, an inner sheath and a locking ring. The locking ring is switchable between an advancement position and a delivery position. The stent graft delivery device is employed in methods for endovascular delivery of stent grafts.

Abstract: A vascular repair device assembly includes a main prostheses, first internal prostheses, an optional second internal prostheses, and at least two sub-prostheses. Methods for delivering vascular repair devices include delivering a vascular repair device through a blood vessel to the aneurysm site, aligning a proximal open end of a main prosthesis cranially to the site of the aneurysm patient and directing a distal end of at least one additional one vascular repair device through a proximal end of at least a first internal lumen, and aligning the proximal end of the additional vascular repair device into a distal end of the at least one sub-prosthesis.

Abstract: A stent graft delivery device includes a handle body, a distal handle, a proximal handle, a guidewire lumen, a nose cone, a rigid outer catheter, a graft push lumen, a sheath lumen, an inner sheath and a locking ring. The locking ring is switchable between an advancement position and a delivery position. The stent graft delivery device is employed in methods for endovascular delivery of stent grafts.

Abstract: A vascular repair device assembly includes a main prostheses, first internal prostheses, an optional second internal prostheses, and at least two sub-prostheses. Methods for delivering vascular repair devices include delivering a vascular repair device through a blood vessel to the aneurysm site, aligning a proximal open end of a main prosthesis cranially to the site of the aneurysm patient and directing a distal end of at least one additional one vascular repair device through a proximal end of at least a first internal lumen, and aligning the proximal end of the additional vascular repair device into a distal end of the at least one sub-prosthesis.

Abstract: A system for implanting a prosthesis includes a control lumen and a nose cone affixed at a distal end of the control lumen. At least one supporting wire is affixed at one end, is substantially parallel to a major axis of the control lumen and is free at an opposite end, wherein the free end of at least one of the supporting wires is arcuate. Alternatively, a system for implanting a prosthesis includes at least one suture extending from a nose cone affixed to a distal end of a control lumen. The suture extends from the nose cone to a proximal end to a stent graft extending about the control lumen and from the stent graft to a fixed location on the control lumen. The suture is releasable from the stent graft by remote activation, whereby the suture separates from the nose cone to thereby deploy the stent graft.

Abstract: A system for implanting a prosthesis includes a prosthesis that extends about a major longitudinal axis and an alignment device connected to the prosthesis. The alignment device appears asymmetric across a plane coplanar to a longitudinal axis of the prosthesis when viewed both along the plane and transversely to the longitudinal axis of the prosthesis delivery and also lies in a plane parallel to and spaced apart from the longitudinal axis of the prosthesis. The alignment device is visible to a user, thereby indicating a rotational and an axial position of the prosthesis with respect to the treatment site prior to implantation of the prosthesis at a treatment site. In an embodiment, the system includes a guidewire catheter that is asymmetric along a major longitudinal axis.

Abstract: A prosthesis implanting system includes a delivery sheath for receiving the prosthesis and delivering it to the treatment site and an alignment device on the sheath visible to a user for indicating a rotational and an axial position of the sheath with respect to the treatment site. The alignment device is part of a delivery assembly slidably disposed in a handle.

Abstract: A system for implanting a prosthesis includes a control lumen and a nose cone affixed at a distal end of the control lumen. At least one supporting wire is affixed at one end, is substantially parallel to a major axis of the control lumen and is free at an opposite end, wherein the free end of at least one of the supporting wires is arcuate.

Abstract: A method for implanting a prosthesis centrally within a curved lumen includes loading a prosthesis into a delivery sheath, advancing the sheath in a patient towards the curved lumen to place at least the proximal end of the prosthesis within the curved lumen, and centering the proximal end of the prosthesis and/or the distal end of the sheath within the curved lumen. In a first advancing step, the outer catheter containing the inner sheath is advanced together towards the curved lumen to a location proximal of the curved lumen and, in a second advancing step, the inner sheath containing the prosthesis is advanced into the curved lumen to place at least the proximal end within the curved lumen while the outer catheter substantially remains at the location. After centering, the proximal end of the prosthesis is deployed centered within the curved lumen.

Abstract: At least one of axial stiffness (i.e. bending stiffness) and radial stiffness of a luminal stent of a luminal stent assembly, or of the luminal stent assembly, linking a fenestrated aortic prosthesis to a branch of a branched artery, decreases with increasing distance from a proximal end of the luminal stent or the luminal stent assembly, and a method of their use implants the luminal stent, the luminal stent, or a luminal stent system that includes at least one of the luminal stent or stent assembly in a branched artery to therapeutically treat a diseased tissue at the branched artery.

Abstract: A method for implanting a prosthesis centrally within a curved lumen includes loading a prosthesis into a delivery sheath, advancing the sheath in a patient towards the curved lumen to place at least the proximal end of the prosthesis within the curved lumen, and centering the proximal end of the prosthesis and/or the distal end of the sheath within the curved lumen. In a first advancing step, the outer catheter containing the inner sheath is advanced together towards the curved lumen to a location proximal of the curved lumen and, in a second advancing step, the inner sheath containing the prosthesis is advanced into the curved lumen to place at least the proximal end within the curved lumen while the outer catheter substantially remains at the location. After centering, the proximal end of the prosthesis is deployed centered within the curved lumen.

Abstract: A vascular repair device assembly includes a main prostheses, first internal prostheses, an optional second internal prostheses, and at least two sub-prostheses. Methods for delivering vascular repair devices include delivering a vascular repair device through a blood vessel to the aneurysm site, aligning a proximal open end of a main prosthesis cranially to the site of the aneurysm patient and directing a distal end of at least one additional one vascular repair device through a proximal end of at least a first internal lumen, and aligning the proximal end of the additional vascular repair device into a distal end of the at least one sub-prosthesis.

Abstract: A vascular repair device assembly includes a main prostheses, first internal prostheses, an optional second internal prostheses, and at least two sub-prostheses. Methods for delivering vascular repair devices include delivering a vascular repair device through a blood vessel to the aneurysm site, aligning a proximal open end of a main prosthesis cranially to the site of the aneurysm patient and directing a distal end of at least one additional one vascular repair device through a proximal end of at least a first internal lumen, and aligning the proximal end of the additional vascular repair device into a distal end of the at least one sub-prosthesis.

Abstract: A stent graft delivery device includes a handle body, a distal handle, a proximal handle, a guidewire lumen, a nose cone, a rigid outer catheter, a graft push lumen, a sheath lumen, an inner sheath and a locking ring. The locking ring is switchable between an advancement position and a delivery position. The stent graft delivery device is employed in methods for endovascular delivery of stent grafts.

Abstract: An aortic graft assembly includes a tubular component that defines a wall aperture having a proximal end that extends perpendicular to a major longitudinal axis of the tubular aortic component, and a tunnel graft connected to the wall of the tubular aortic component and extending from the wall aperture toward a proximal end of the tubular aortic component. The aortic graft assembly is delivered to a patient through the wall aperture and into interfering relation with the tunnel graft to treat aortic aneurysms.