Patents by Inventor Samuel Kaufman
Samuel Kaufman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11715494Abstract: A computer-implemented method, computer program product and computing system for recording video information on the computing device during a monitored event. Execution information is recorded on the computing device during the monitored event. The video information and the execution information are temporally synchronized to form temporally-synchronized diagnostic content.Type: GrantFiled: June 22, 2020Date of Patent: August 1, 2023Assignee: MIRUNI INC.Inventors: Samuel Kaufman, Joanna Kaufman, Joseph Papperello
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Patent number: 11370825Abstract: This disclosure describes, generally, a modified form of CD16, genetically-modified cells that express the modified CD16, and methods that involve the genetically-modified cells. The modified form of CD16 can exhibit increased anti-tumor and/or anti-viral activity due, at least in part, to reduced susceptibility to ADAM17-mediated shedding upon NK cell stimulation.Type: GrantFiled: April 19, 2021Date of Patent: June 28, 2022Assignee: Regents of the University of MinnesotaInventors: Bruce Kenneth Walcheck, Dan Samuel Kaufman, Jianming Wu, Yawu Jing, Zhenya Ni
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Publication number: 20210332103Abstract: This disclosure describes, generally, a modified form of CD16, genetically-modified cells that express the modified CD16, and methods that involve the genetically-modified cells. The modified form of CD16 can exhibit increased anti-tumor and/or anti-viral activity due, at least in part, to reduced susceptibility to ADAM17-mediated shedding upon NK cell stimulation.Type: ApplicationFiled: April 19, 2021Publication date: October 28, 2021Inventors: Bruce Kenneth Walcheck, Dan Samuel Kaufman, Jianming Wu, Yawu Jing, Zhenya Ni
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Publication number: 20200388303Abstract: A computer-implemented method, computer program product and computing system for recording video information on the computing device during a monitored event. Execution information is recorded on the computing device during the monitored event. The video information and the execution information are temporally synchronized to form temporally-synchronized diagnostic content.Type: ApplicationFiled: June 22, 2020Publication date: December 10, 2020Inventors: Samuel Kaufman, Joanna Kaufman, Joseph Papperello
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Publication number: 20200291125Abstract: This disclosure describes chimeric antigen receptors for expression in a Natural Killer (NK) cell, pharmaceutical compositions that include NK cells (and/or iPSCs) modified to express a chimeric antigen receptor, and methods involving such chimeric antigen receptors. Generally, the chimeric antigen receptor includes an ectodomain that includes an antigen recognition region, a transmembrane domain linked to the ectodomain, and an endodomain linked to the transmembrane domain. The endodomain can include a signaling peptide that activates an NK cell.Type: ApplicationFiled: April 1, 2020Publication date: September 17, 2020Inventors: Dan Samuel KAUFMAN, David Lee LAMPI HERMANSON, Branden Scott MORIARITY
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Patent number: 10691524Abstract: A computer-implemented method, computer program product and computing system for recording video information on the computing device during a monitored event. Execution information is recorded on the computing device during the monitored event. The video information and the execution information are temporally synchronized to form temporally-synchronized diagnostic content.Type: GrantFiled: July 28, 2017Date of Patent: June 23, 2020Assignee: Bugreplay Inc.Inventors: Samuel Kaufman, Joanna Kaufman, Joseph Papperello
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Patent number: 10640570Abstract: This disclosure describes chimeric antigen receptors for expression in a Natural Killer (NK) cell, pharmaceutical compositions that include NK cells (and/or iPSCs) modified to express a chimeric antigen receptor, and methods involving such chimeric antigen receptors. Generally, the chimeric antigen receptor includes an ectodomain that includes an antigen recognition region, a transmembrane domain linked to the ectodomain, and an endodomain linked to the transmembrane domain. The endodomain can include a signaling peptide that activates an NK cell.Type: GrantFiled: January 28, 2016Date of Patent: May 5, 2020Assignee: Regents of the University of MinnesotaInventors: Dan Samuel Kaufman, David Lee Lampi Hermanson, Branden Scott Moriarity
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Publication number: 20200017570Abstract: This disclosure describes, generally, a modified form of CD16, genetically-modified cells that express the modified CD16, and methods that involve the genetically-modified cells. The modified form of CD16 can exhibit increased anti-tumor and/or anti-viral activity due, at least in part, to reduced susceptibility to ADAM17-mediated shedding upon NK cell stimulation.Type: ApplicationFiled: September 19, 2019Publication date: January 16, 2020Inventors: Bruce Kenneth Walcheck, Dan Samuel Kaufman, Jianming Wu, Yawu Jing, Zhenya Ni
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Patent number: 10464989Abstract: This disclosure describes, generally, a modified form of CD 16, genetically-modified cells that express the modified CD 16, and methods that involve the genetically-modified cells. The modified form of CD 16 can exhibit increased anti-tumor and/or anti- viral activity due, at least in part, to reduced susceptibility to ADAM17-mediated shedding upon NK cell stimulation.Type: GrantFiled: March 27, 2015Date of Patent: November 5, 2019Assignee: Regents of the University of MinnesotaInventors: Bruce Kenneth Walcheck, Dan Samuel Kaufman, Jianming Wu, Yawu Jing, Zhenya Ni
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Publication number: 20180032389Abstract: A computer-implemented method, computer program product and computing system for recording video information on the computing device during a monitored event. Execution information is recorded on the computing device during the monitored event. The video information and the execution information are temporally synchronized to form temporally-synchronized diagnostic content.Type: ApplicationFiled: July 28, 2017Publication date: February 1, 2018Inventors: Samuel Kaufman, Joanna Kaufman, Joseph Papperello
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Publication number: 20180002438Abstract: This disclosure describes chimeric antigen receptors for expression in a Natural Killer (NK) cell, pharmaceutical compositions that include NK cells (and/or iPSCs) modified to express a chimeric antigen receptor, and methods involving such chimeric antigen receptors. Generally, the chimeric antigen receptor includes an ectodomain that includes an antigen recognition region, a transmembrane domain linked to the ectodomain, and an endodomain linked to the transmembrane domain. The endodomain can include a signaling peptide that activates an NK cell.Type: ApplicationFiled: January 28, 2016Publication date: January 4, 2018Inventors: Dan Samuel KAUFMAN, David Lee LAMPI HERMANSON, Branden Scott MORIARITY
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Publication number: 20170174743Abstract: This disclosure describes, generally, a modified form of CD 16, genetically-modified cells that express the modified CD 16, and methods that involve the genetically-modified cells. The modified form of CD 16 can exhibit increased anti-tumor and/or anti- viral activity due, at least in part, to reduced susceptibility to ADAM17-mediated shedding upon NK cell stimulation.Type: ApplicationFiled: March 27, 2015Publication date: June 22, 2017Inventors: Bruce Kenneth Walcheck, Dan Samuel Kaufman, Jianming Wu, Yawu Jing, Zhenya Li
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Publication number: 20170121683Abstract: Methods for enhancing and disrupting activity of the aryl hydrocarbon receptor (AHR) and cells having disrupted or enhanced AHR activity. The methods and cells may be used to enhance production of specific cell populations during hemato-endothelial cell or hemato-lymphoid cell development.Type: ApplicationFiled: November 3, 2016Publication date: May 4, 2017Inventors: Dan Samuel Kaufman, Mathew George Angelos
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Publication number: 20090319629Abstract: A method and a system re-classify a delivered message to permit an action to be taken on the delivered message, based on the re-classification. In an example embodiment, a mail transfer agent may receive a message directed to a mail store and a message classifier may generate a representation of at least a portion of the message and classify the message using a representation of the message and a characteristic associated with the representation. In some example embodiments, the mail transfer agent may deliver the message to a message store, based on the classification of the message. Subsequent to the mail transfer agent delivering the message to the message store, a message re-classifier may access a further characteristic associated with the representation and re-classify the message based on the representation and the second characteristic.Type: ApplicationFiled: June 23, 2009Publication date: December 24, 2009Inventors: James Allan de Guerre, Philippe Le Rohellec, Lev Samuel Kaufman, Michal Adam Bujak
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Patent number: 6122264Abstract: A method and system are provided for reducing skew-group blocking in a CDMA wireless system, or similar such blocking in any information transmission system characterized by packet arrivals associated with a given connection occurring at multiples of a fixed timing interval (frame), and where packet arrivals associated with different connections need to be dispersed within that interval. The system assigns competing connections to sub-intervals within a timing interval for such an information transmission systems, and causes a request from an information source for assignment to a specific sub-interval to be acted on pursuant to an evaluation of the impact that the grant of such a request for the specific sub-interval assignment will have on a transmission delay for packets assigned to succeeding sub-intervals in the timing interval.Type: GrantFiled: September 29, 1997Date of Patent: September 19, 2000Assignee: Lucent Technologies, Inc.Inventors: Joseph Samuel Kaufman, Sanjiv Nanda
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Patent number: 6108321Abstract: An interference based dynamic channel assignment scheme for a wireless communication network, for self configuring dynamic channel assignment of a plurality of channels, comprises the steps of: prioritizing a channel list and prioritizing a selected subset of the prioritized channel list. In further enhancements of the present invention, prioritizing a channel list is distributed on a per cell/sector basis so that prioritization is independent of frequency usage information from other cells/sectors and prioritization is based upon uplink and downlink characteristics.Type: GrantFiled: March 5, 1997Date of Patent: August 22, 2000Assignee: Lucent Technologies Inc.Inventors: Nefatiti Anderson, Simon C. Borst, Lynell E. Cannell, Terry Si-Fong Cheng, Lindsey Chew, Sudheer A. Grandhi, Chih-Lin I, Joseph Samuel Kaufman, Boris Dmitrievich Lubachevsky, Balakrishnan Narendran, Donna M. Sand
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Patent number: 4291835Abstract: A very fine fog or mist producing nozzle is disclosed wherein two or more balls rotate in an enclosed orifice chamber, into which the fluid is tangentially injected, to break up the fluid into a very fine mist. The nozzle produces a mist of much finer atomized particles than the prior art devices to thereby increase the efficiency of a fuel burner or similar device. The nozzle is such that it may be readily attached to an existing fluid flow line without major alterations.Type: GrantFiled: December 7, 1979Date of Patent: September 29, 1981Inventor: Samuel Kaufman
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Patent number: 4200536Abstract: An underdrain assembly for a filter tank includes a plurality of spirally shaped hollow tubular elements of substantially equal length having capped terminal ends and equally spaced perforations in lower sides thereof. The elements are equally spaced apart so that the perforations in adjacent elements are spaced substantially the same as the perforations in the tubular elements. Backwash water fed out through such perforations is therefore distributed during a backwashing operation substantially uniformly throughout the filter bed of the tank overlying the underdrain assembly so that the entirety of the filter bed is completely and uniformly backwashed.Type: GrantFiled: August 22, 1978Date of Patent: April 29, 1980Inventor: Samuel Kaufman
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Patent number: 4008550Abstract: For setting the sockets for swimming pool ladders in the deck of the pool, a pair of sockets is provided which are connected to a channel bar formed of sheet metal with upwardly directed and inwardly slanting longitudinal flanges. This is then set at the proper position, and secured to the ground by deformed steel rods running through holes in the sheet metal. The channel is filled with grout which when set holds the bar and the sockets securely in place. The sockets are filled with sand, which is removed by the use of a hose after the deck has been poured, screeded and cured.Type: GrantFiled: September 19, 1974Date of Patent: February 22, 1977Inventor: Samuel Kaufman
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Patent number: 4004301Abstract: A removably mounted swimming pool safety rope anchoring device for a pool with a metal, wood or fiberglass wall and a vinyl liner includes a stem having an enlarged portion at one end, and threaded along its whole exterior; a nut which can be threaded on the smaller end; and an eye part having an internally threaded socket portion which threadedly engages the enlarged portion of the stem and an eye rigid with the socket portion. This is inserted through the wall during the installation of the pool with the nut on the outside and the stem extending through a hole in the pool wall. A lock washer and a sealing washer are arranged between the nut and the pool wall. A hole is cut in the liner to allow the enlarged portion to project through, and the portion of the liner around the enlarged portion is overlaid and clamped by the socket portion. This permits the eye part to be removed and the liner to be changed without requiring access to the nut on the outside of the wall.Type: GrantFiled: August 4, 1975Date of Patent: January 25, 1977Inventor: Samuel Kaufman