Abstract: A drive train for a wind-up injection device is described. The drive train includes a torsional energy storage adapted to be loaded or unloaded by a rotatable element, a rotatable user handle, a rotationally driveable expelling mechanism adapted to expel the liquid drug, and a clutch element coupled with the torsional energy storage via the rotatable element and including a ratchet for maintaining the rotatable element at one of a number of discrete angular positions against the torque of the torsional energy storage. The clutch element is adapted to transmit the torque from the user handle to the torsional energy storage, or alternatively from the torsional energy storage to the expelling mechanism. The ratchet is switchable from one position to an adjacent position by a torque transmitted from the user handle to the torsional energy storage. The drive train is adapted to dampen torque peaks visco-elastically and/or visco-frictionally.

Abstract: A drive train for a wind-up injection device is described. The drive train includes a torsional energy storage adapted to be loaded or unloaded by a rotatable element, a rotatable user handle, a rotationally driveable expelling mechanism adapted to expel the liquid drug, and a clutch element coupled with the torsional energy storage via the rotatable element and including a ratchet for maintaining the rotatable element at one of a number of discrete angular positions against the torque of the torsional energy storage. The clutch element is adapted to transmit the torque from the user handle to the torsional energy storage, or alternatively from the torsional energy storage to the expelling mechanism. The ratchet is switchable from one position to an adjacent position by a torque transmitted from the user handle to the torsional energy storage. The drive train is adapted to dampen torque peaks visco-elastically and/or visco-frictionally.

Abstract: A drug delivery device comprising: a housing; a cylindrical member rotatably supported within the housing; and a plurality of sensors; wherein: the outer surface of the cylindrical member is provided with a single track, the track forming an encoder and having a plurality of first track segments and a plurality of second track segments arranged along the length of the track which are respectively capable of inducing first and second responses in the sensors; and in each rotational position of the cylindrical member relative to the housing at least one different first track segment is capable of inducing a first response in at least one said sensor, thereby enabling the rotational position of the cylindrical member relative to the housing to be determined.

Abstract: The present disclosure is generally directed to a drug delivery device for selecting and dispensing a number of user variable doses of a medicament. The device comprises a housing and at least two separate component parts, wherein for example at least one of these component parts performs a movement relative to the housing during dose setting and for example at least one of these component parts performs a movement relative to the housing during dose dispensing, and wherein the relative movement of the at least two separate component parts with respect to each other during dose setting differs from the relative movement of the at least two separate component parts with respect to each other during dose dispensing.

Abstract: A drive train (T) for a wind-up injection device (1) for injecting a liquid drug comprises a torsional energy storage (9) adapted to be loaded or unloaded by a rotatable element (6), a rotatable user handle (8), a rotationally driveable expelling mechanism (5) adapted to expel the liquid drug and a clutch element (12) coupled with the torsional energy storage (9) via the rotatable element (6) and comprising a ratchet (12.4) for maintaining the rotatable element (6) at one of a number of discrete angular positions against the torque of the torsional energy storage (9). The clutch element (12) is adapted to transmit a torque from the user handle (8) via the rotatable element (6) to the torsional energy storage (9) or alternatively from the torsional energy storage (9) via the rotatable element (6) to the expelling mechanism (5), wherein the ratchet (12.4) is switchable from one position to an adjacent position by a torque transmitted from the user handle (8) to the torsional energy storage (9).

Abstract: A drug delivery device comprising: a housing; a cylindrical member rotatably supported within the housing; and a plurality of sensors; wherein: the outer surface of the cylindrical member is provided with a single track, the track forming an encoder and having a plurality of first track segments and a plurality of second track segments arranged along the length of the track which are respectively capable of inducing first and second responses in the sensors; and in each rotational position of the cylindrical member relative to the housing at least one different first track segment is capable of inducing a first response in at least one said sensor, thereby enabling the rotational position of the cylindrical member relative to the housing to be determined.

Abstract: A dose setting mechanism comprising a first element and a second element; the first element being moveable with respect to the second element; the first element and the second element being coupled by a ratchet mechanism allowing motion of the first element with respect to the second element from a first position to a second position only in a first direction while preventing motion in a second direction that is opposite to the first direction; once passing the second position, the first element being moveable with respect to the second element in the first direction and in the second direction.

Abstract: The present disclosure is generally directed to a drug delivery device for selecting and dispensing a number of user variable doses of a medicament. The device comprises a housing (10), a dose selector (80) operable to set a dose by rotation relative to the housing (10), a number sleeve (60) arranged within the housing (10) such that at least a portion of the number sleeve (60) is visible through a first aperture (11b) in the housing (10), and a piston rod (30) coupled to the housing (10) and to a drive sleeve (40). Rotation of the drive sleeve (40) relative to the housing (10) causes the piston rod (30) to translate relative to the housing (10). The piston rod (30) is coupled to the housing (10) via a threaded interface (16, 31) with at least two different pitches.

Abstract: The present disclosure relates to a drug delivery device, comprising a housing, a cartridge, the cartridge containing a drug in a quantity sufficient for a plurality of doses of the drug, a bung, the bung being movably retained within the cartridge to dispense a dose of the drug from the cartridge upon movement of the bung with respect to the cartridge, and a drive mechanism, the drive mechanism being operable to transfer a driving force to the bung to dispense the dose of the drug from the cartridge. The drug delivery device is configured such that the maximal driving force which is transferrable to the bung via the drive mechanism varies and is adjusted to the current position of the bung within the cartridge.

Abstract: A dose setting mechanism for a drug delivery device includes a primary drug delivery assembly and a secondary drug delivery assembly. The dose setting mechanism includes a primary dose dial component for setting a dose in the primary drug delivery assembly and a secondary dose dial component for setting a dose in the secondary drug delivery assembly. The primary dose dial component and the secondary dose dial component are configured to rotate during dose setting. A gear mechanism is configured such that in a first phase of the dose setting, rotation of the primary dose dial component is transferred to the secondary dose dial component and such that in a second phase of the dose setting, the secondary dose dial component is decoupled from the primary dose dial component such that rotation of the primary dose dial component is prevented from being transferred to the secondary dose dial component.

Abstract: A drug delivery device comprising: a housing; a plurality of sensors; and a cylindrical member supported within the housing, an outer surface of said cylindrical member being provided with a helical track, the helical track comprising track segments of a first type and track segments of a second type, the first and second types of track segments being respectively capable of inducing first and second responses in the sensors; wherein: the helical track has a width; the helical track includes across the width of the helical track at least one track segment of the first type and at least one track segment of the second type at plural positions along a length of the helical track; the device is configured such that during a first phase of a drug delivery operation the helical track is moved axially, without rotation, relative to the plurality of sensors between a first position and a second position, and during a second phase of the drug delivery operation the track is moved helically relative to the plurality o

Abstract: The invention is directed to drug delivery device comprising a primary drug delivery assembly (3) with a primary dose dial sleeve (17) and a secondary drug delivery assembly (4) with a secondary drive sleeve (24). For user selection, a selection switch (48) is movable between a first, a second and a third position and a clutch (49) is connected to the selection switch (48) such that movement of the selection switch (48) causes rotation of the clutch (49). A secondary drive sleeve (24) is configured to rotate and to engage the clutch (49), wherein the clutch (49) is configured to transfer rotation to the secondary drive sleeve (24) when the selection switch (48) is moved from the first position into the second position and to disengage from the secondary drive sleeve (24) when the selection switch (48) is moved from the first into the third position.

Abstract: The disclosure is directed to a differential gear mechanism for a drug delivery device with a primary drug delivery assembly and a secondary drug delivery assembly, wherein the primary drug delivery assembly comprises a primary dose dial sleeve and wherein the secondary drug delivery assembly comprises a secondary drive sleeve. The disclosure is also directed to a respective drug delivery device.

Abstract: A drug delivery device for administering a drug is presented having a body adapted to retain a cartridge containing a drug, at least one electrical unit and a port for electrically contacting the electrical unit, an adapter for attaching an injection needle to the drug delivery device, a safety mechanism arranged to prevent contacting the electrical unit through the port whilst an injection needle is in fluid communication with the cartridge and arranged to prevent establishing a fluid communication between an injection needle and the cartridge whilst the port is configured to allow contacting the electrical unit.

Abstract: The present disclosure is generally directed to a drug delivery device for selecting and dispensing a number of user variable doses of a medicament comprising a clicker arrangement. The device comprises a housing (10), a dose selector (80) operable to set a dose by rotation relative to the housing (10), a number sleeve (60) coupled to the dose selector (80) and arranged within the housing (10) such that at least a portion of the number sleeve (60) is visible through a first aperture (11b) in the housing (10), a piston rod (30) coupled to the housing (10) and to a drive sleeve (40) such that rotation of the drive sleeve (40) relative to the housing (10) causes the piston rod (30) to translate relative to the housing (10), a clutch (120) arranged between the number sleeve (60) and the drive sleeve (40), and a dispense clicker comprising a flexible arm (123) and a toothed profile (75). The device further comprises a button (70) operable to effect dose dispensing.

Abstract: The present disclosure is generally directed to a drug delivery device for selecting and dispensing a number of user variable doses of a medicament. The device comprises a housing and at least two separate component parts, wherein for example at least one of these component parts performs a movement relative to the housing during dose setting and for example at least one of these component parts performs a movement relative to the housing during dose dispensing, and wherein the relative movement of the at least two separate component parts with respect to each other during dose setting differs from the relative movement of the at least two separate component parts with respect to each other during dose dispensing.

Abstract: The present disclosure is generally directed to a trigger mechanism for initiating dispensing doses of a medicament from a drug delivery device. The trigger mechanism includes a trigger element movable in a first direction relative to a counter element. To provide a feedback to a user of the trigger mechanism, the trigger element includes a first interference member and the counter element includes a second interference member located with respect to the first interference member such that upon movement of the trigger element relative to the counter element the first interference member contacts and passes over the second interference member, thereby generating an audible and/or tactile feedback. Further, the disclosure includes a drug delivery device for selecting and dispensing a number of user variable doses of a medicament comprising such a trigger mechanism.

Abstract: The present disclosure relates to a drug delivery device, comprising a housing, a cartridge, the cartridge containing a drug in a quantity sufficient for a plurality of doses of the drug, a bung, the bung being movably retained within the cartridge to dispense a dose of the drug from the cartridge upon movement of the bung with respect to the cartridge, and a drive mechanism, the drive mechanism being operable to transfer a driving force to the bung to dispense the dose of the drug from the cartridge. The drug delivery device is configured such that the maximal driving force which is transferrable to the bung via the drive mechanism varies and is adjusted to the current position of the bung within the cartridge.

Abstract: A dose setting mechanism comprising a first element and a second element; the first element being moveable with respect to the second element; the first element and the second element being coupled by a ratchet mechanism allowing motion of the first element with respect to the second element from a first position to a second position only in a first direction while preventing motion in a second direction that is opposite to the first direction; once passing the second position, the first element being moveable with respect to the second element in the first direction and in the second direction.

Abstract: The present disclosure concerns a mechanism for setting a dose of a medicament for a variable dose drug delivery device, comprising: a housing, a sleeve component configured to rotate relative to the housing during a dose setting operation, and a stop member which is configured to limit a total amount of possible rotation of the sleeve component to a maximum and, thereby, to limit a maximum settable dose, wherein the stop member is configured to allow varying the maximum which determines the total amount of possible rotation of the sleeve component.