Patents by Inventor Sandra N. Lehrman

Sandra N. Lehrman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of idiopathic thrombocytopaenic purpura
    Patent number: 5145840
    Abstract: A method of treating idiopathic thrombocytopaenia purpura with 2',3'-dideoxy-3'-azidonucleosides, in particular 3'-azido-3'-deoxythymidine, is disclosed.
    Type: Grant
    Filed: April 2, 1991
    Date of Patent: September 8, 1992
    Assignee: Burroughs Wellcome Co.
    Inventors: Leone E. Kirk, III, Dannie H. King, Richard H. Clemons, Sandra N. Lehrman, David W. Barry
  • Treatment of human viral infections
    Patent number: 5086044
    Abstract: Treatment of AIDS or humans carrying or infected with the AIDS virus or having antibodies to the AIDS virus is disclosed using the compound 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof. Also disclosed is the use of the 5'-mono-, di- and triphosphate of 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof for the same purpose. Additionally, there is disclosed the treatment of Kaposi's sarcoma with 3'-azido-3'-deoxythymidine (AZT) and the synergistic activity in the treatment of humans infected with HTLV-III of AZT and interferon as well as AZT and acyclovir.
    Type: Grant
    Filed: April 18, 1990
    Date of Patent: February 4, 1992
    Assignee: Burroughs Wellcome Co.
    Inventors: Janet L. Rideout, David W. Barry, Sandra N. Lehrman, Martha H. St. Clair, Phillip A. Furman
  • Methods for treating viral infection
    Patent number: 5017577
    Abstract: The present invention relates to certain novel 8-phenylxanthines substituted in the 3 or 4 position of the phenyl group by an alkenylene, alkenyleneoxy, alkynylene or alkynyleneoxy bearing a terminal acidic grouping, and to their use in human and veterinary therapy, particularly for conditions associated with the cell surface effects of adenosine and in antiviral, especially antiretroviral, chemotherapy.
    Type: Grant
    Filed: July 19, 1989
    Date of Patent: May 21, 1991
    Assignee: Burroughs Wellcome Co.
    Inventors: Susan M. Daluge, Harry J. Leighton, Sandra N. Lehrman
  • Method for treating viral infections
    Patent number: 5015647
    Abstract: The present invention relates to certain novel 8-phenylxanthines substituted in the 3 or 4 position of the phenyl group by an alkenylene, alkenyleneoxy, alkynylene or alkynyleneoxy bearing a terminal acidic grouping, and to their use in human and veterinary therapy, particularly for conditions associated with the cell surface effects of adenosine and in antiviral, especially antiretroviral, chemotherapy.
    Type: Grant
    Filed: July 19, 1989
    Date of Patent: May 14, 1991
    Assignee: Burroughs Wellcome Co.
    Inventors: Susan M. Daluge, Harry J. Leighton, Sandra N. Lehrman
  • Treatment of human viral infections
    Patent number: 4874609
    Abstract: Treatment of AIDS or humans carrying or infected with the AIDS virus or having antibodies to the AIDS virus is disclosed using the compound 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof.Also disclosed is the use of the 5'-mono-, di- and triphosphate of 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof for the same purpose.
    Type: Grant
    Filed: February 8, 1988
    Date of Patent: October 17, 1989
    Assignee: Burroughs Wellcome Co.
    Inventors: Janet L. Rideout, David W. Barry, Sandra N. Lehrman, Martha H. St. Clair, Phillip A. Furman
  • Treatment of human viral infections
    Patent number: 4857511
    Abstract: Treatment of AIDS or humans carrying or infected with the AIDS virus or having antibodies to the AIDS virus is disclosed using the compound 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof.Also disclosed is the use of the 5'-mono-, di- and triphosphate of 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof for the same purpose.
    Type: Grant
    Filed: February 8, 1988
    Date of Patent: August 15, 1989
    Assignee: Burroughs Wellcome Co.
    Inventors: Janet L. Rideout, David W. Barry, Sandra N. Lehrman, Martha H. St. Clair, Phillip A. Furman
  • Treatment of human viral infections
    Patent number: 4847244
    Abstract: Treatments of AIDS or humans carrying or infected with the AIDS virus or having antibodies to the AIDS virus is disclosed using the compound 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof.Also disclosed is the use of the 5'-mono-, di- and triphosphate of 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof for the same purpose.
    Type: Grant
    Filed: October 20, 1987
    Date of Patent: July 11, 1989
    Assignee: Burroughs Wellcome Co.
    Inventors: Janet L. Rideout, David W. Barry, Sandra N. Lehrman, Martha H. St. Clair, Phillip A. Furman
  • Treatment of human viral infections
    Patent number: 4837208
    Abstract: Treatment of AIDS or humans carrying or infected with the AIDS virus or having antibodies to the AIDS virus is disclosed using the compound 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof.Also disclosed is the use of the 5'-mono-, di- and triphosphate of 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof for the same purpose.
    Type: Grant
    Filed: October 20, 1987
    Date of Patent: June 6, 1989
    Assignee: Burroughs Wellcome Co.
    Inventors: Janet L. Rideout, David W. Barry, Sandra N. Lehrman, Martha H. St. Clair, Phillip A. Furman
  • Treatment of human viral infections
    Patent number: 4833130
    Abstract: Treatment of AIDS or humans carrying or infected with the AIDS virus or having antibodies to the AIDS virus is disclosed using the compound 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof.Also disclosed is the use of the 5'-mono, di- and triphosphate of 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof for the same purpose.
    Type: Grant
    Filed: October 20, 1987
    Date of Patent: May 23, 1989
    Assignee: Burroughs Wellcome Co.
    Inventors: Janet L. Rideout, David W. Barry, Sandra N. Lehrman, Martha H. St. Clair, Phillip A. Furman
  • Treatment of human viral infection
    Patent number: 4828838
    Abstract: Treatment of AIDS or humans carrying or infected with the AIDS virus or having antibodies to the AIDS virus is disclosed using the compound 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof.Also disclosed is the use of 5'-mono-, di- and triphosphate of 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof for the same purpose.
    Type: Grant
    Filed: October 21, 1987
    Date of Patent: May 9, 1989
    Assignee: Burroughs Wellcome Co.
    Inventors: Janet L. Rideout, David W. Barry, Sandra N. Lehrman, Martha H. St. Clair, Phillip A. Furman
  • Treatment of human viral infections
    Patent number: 4818538
    Abstract: Treatment of AIDS or humans carrying or infected with the AIDS virus or having antibodies to the AIDS virus is disclosed using the compound 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof.Also disclosed is the use of the 5.dbd.-mono-, di- and triphosphate of 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof for the same purpose.
    Type: Grant
    Filed: October 21, 1987
    Date of Patent: April 4, 1989
    Assignee: Burroughs Wellcome Co.
    Inventors: Janet L. Rideout, David W. Barry, Sandra N. Lehrman, Martha H. St. Clair, Phillip A. Furman
  • Treatment of human viral infections
    Patent number: 4818750
    Abstract: Treatment of AIDS or humans carrying or infected with the AIDS virus or having antibodies to the AIDS virus is disclosed using the compound 3'-azido-3'-deoxythymidine or a pharmaceutically basic salt thereof.Also disclosed is the use of the 5'-mono-, di- and triphosphate of 3'-azido-3'-dexoythymidine or a pharmaceutically acceptable basic salt thereof for the same purpose.
    Type: Grant
    Filed: October 20, 1987
    Date of Patent: April 4, 1989
    Assignee: Burroughs Wellcome Co.
    Inventors: Janet L. Rideout, David W. Barry, Sandra N. Lehrman, Martha H. St. Clair, Phillip A. Furman
  • Treatment of feline viral infections
    Patent number: 4780453
    Abstract: Treatment of cats carrying or infected with the Feline Leukemia virus or having antibodies to the Feline leukemia virus is disclosed using the compound 3'-azido''-deoxythymidine or a pharmaceutically acceptable basic salt thereof.Also disclosed is the use of the 5'-mono-, di- and triphosphate of 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof for the same purpose.
    Type: Grant
    Filed: December 23, 1986
    Date of Patent: October 25, 1988
    Assignee: Burroughs Wellcome Co.
    Inventors: Janet L. Rideout, David W. Barry, Sandra N. Lehrman, Martha H. St. Clair, Phillip A. Furman
  • Treatment of human viral infections
    Patent number: 4724232
    Abstract: Treatment of AIDS or humans carrying or infected with the AIDS virus or having antibodies to the AIDS virus is disclosed using the compound 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof.Also disclosed is the use of the 5'-mono-, di- and triphosphate of 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof for the same purpose.
    Type: Grant
    Filed: September 17, 1985
    Date of Patent: February 9, 1988
    Assignee: Burroughs Wellcome Co.
    Inventors: Janet L. Rideout, David W. Barry, Sandra N. Lehrman, Martha H. St. Clair, Phillip A. Furman