Abstract: A wound dressing that includes a contact layer having walls defining a plurality of perforations and a debriding matrix including a polymer and at least one debriding agent is provided herein. Systems, methods and kits using the wound dressing for debriding a tissue site are also provided herein.

Abstract: In one example embodiment, a system for stimulating tissue with the application of temperature-regulated fluid and negative pressure comprises a negative-pressure source adapted to provide negative pressure to a dressing. The system may further comprise a thermoelectric module thermally coupled to a first heat exchange chamber and a second heat exchange chamber and adapted to transfer heat between said heat exchange chambers. The thermoelectric module can be further adapted to maintain a temperature-regulated fluid fluidly coupled to the first heat exchange chamber and the dressing within a predetermined temperature range by adding heat to and extracting heat from the temperature-regulated fluid as it passes through the first heat exchange chamber.

Abstract: A wound dressing that includes a contact layer having walls defining a plurality of perforations and a debriding matrix including a polymer and at least one debriding agent is provided herein. Systems, methods and kits using the wound dressing for debriding a tissue site are also provided herein.