Patents by Inventor Sandrine Hamels

Sandrine Hamels has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7767440
    Abstract: Cover of a hybridization chamber with a peripheral frame with filling and ventilation holes extending from the upper face to the lower face of the frame, a peripheral shoulder outside the filling and ventilation holes on the lower face of the frame, a cover wall arranged within the frame, flush with its lower face and downwardly offset relative to its upper face and which substantially consists of at least one resilient plastics material.
    Type: Grant
    Filed: September 1, 2004
    Date of Patent: August 3, 2010
    Assignee: Eppendorf AG
    Inventors: Martin Seippel, Sandrine Hamels, Christopher VanHuffel
  • Publication number: 20100113301
    Abstract: The present invention is related to a method for the identification and/or the quantification of a target compound obtained from a sample, preferably a biological sample, comprising the steps of putting into contact the target compound with a capture molecule in order in order to allow a specific binding between said target compound with a capture molecule, said capture molecule being fixed upon a surface of a solid support according to an array comprising a density of at least 20 discrete regions per cm2, each of said discrete regions being fixed with one species of capture molecules, performing a reaction leading to a precipitate formed at the location of said binding, determining the possible presence of precipitate(s) in discrete region(s), and correlating the presence of the precipitate(s) at the discrete region(s) with the identification and/or a quantification of said target compound.
    Type: Application
    Filed: December 1, 2009
    Publication date: May 6, 2010
    Applicant: Eppendorf Array Technologies
    Inventors: Jose Remacle, Joseph Demarteau, Nathalie Zammatteo, Isabelle Alexandre, Sandrine Hamels, Yves Houbion, Francoise De Longueville
  • Publication number: 20100099860
    Abstract: The invention relates to a method for the design and/or the preparation of a polynucleotide capture molecule for detecting an amplicon having one strand serving as target to be detected and/or quantified after hybridization on said capture molecule, comprising the steps of: (a) selecting a primer pair defining the amplicon; (b) selecting a specific sequence of 10 to 100 nucleotides within the amplicon, such that said specific sequence defines two non-complementary ends of the amplicon; (c) defining the capture molecule having a capture portion that is complementary to the specific sequence selected in step b), and a spacer portion comprising at least 20 nucleotides; and (d) identifying among the two non-complementary ends of the amplicon a spacer end and a non-spacer end, respectively, such that the spacer end is non-complementary to the spacer portion of the capture molecule, and said spacer end exceeds said non-spacer end by at least 50 bases.
    Type: Application
    Filed: December 14, 2009
    Publication date: April 22, 2010
    Inventors: José Remacle, Sandrine Hamels
  • Publication number: 20090239234
    Abstract: A method for identifying a genetically modified plant by identification and/or quantification of different, multiple nucleotide sequence elements corresponding to at least a portion of an exogenous nucleotide sequence integrated into the genome of the genetically modified plant. The method involves amplifying a nucleic acid sequence element into target nucleic acid sequences, contacting the target nucleic acid sequences with single stranded capture nucleotide sequences, detecting binding of the target nucleotide sequences, constructing a genetic map, and identifying the genetically modified plant.
    Type: Application
    Filed: April 23, 2009
    Publication date: September 24, 2009
    Applicant: Eppendorf Array Technologies S.A.
    Inventors: Jose Remacle, Sandrine Hamels
  • Publication number: 20080293057
    Abstract: The present invention is related to a method, kit and computer program for detecting the presence in a sample of an unspecified Genetically Modified Organism (GMO).
    Type: Application
    Filed: March 31, 2008
    Publication date: November 27, 2008
    Applicant: EPPENDORF ARRAY TECHNOLOGIES S.A.
    Inventors: Jose Remacle, Sandrine Hamels
  • Publication number: 20080145845
    Abstract: The present invention is related to a method and kit (or device) for identifying and/or quantifying in an array mRNA nucleotide sequences related to resistance to antibiotic(s) being expressed in a (micro)organism present in a sample.
    Type: Application
    Filed: December 23, 2005
    Publication date: June 19, 2008
    Applicant: EPPENDORF ARRAY TECHNOLOGIES S.A.
    Inventors: Jose Remacle, Sandrine Hamels, Sophie Burteau
  • Publication number: 20080085515
    Abstract: The present invention is related to a method for identifying and/or quantifying an organism or part of an organism in a sample by detecting a nucleotide sequence specific for said organism, among at least 4 other nucleotide sequences from other organisms or from parts of the organisms.
    Type: Application
    Filed: March 30, 2007
    Publication date: April 10, 2008
    Applicant: Eppendorf Array Technologies SA (EAT)
    Inventors: Jose Remacle, Sandrine Hamels, Nathalie Zammatteo, Isabelle Alexandre, Francoise de Longueville
  • Patent number: 7338763
    Abstract: The invention relates to a method and a kit for the specific identification and/or quantification of one or several among at least 7 organisms or parts thereof, in a biological sample being possibly contaminated by at least 4 other organisms, by detecting at least one nucleotide sequence specific of each of the organisms possibly present in said biological sample, wherein said nucleotide sequence is homologous with at least 4 other nucleotide sequences.
    Type: Grant
    Filed: June 2, 2004
    Date of Patent: March 4, 2008
    Assignee: Eppendorf Array Technologies S.A.
    Inventors: Jose Remacle, Sandrine Hamels, Sophie Burteau, Nathalie Zammatteo
  • Patent number: 7321829
    Abstract: The present invention is related to a method for the identification and/or the quantification of a target compound obtained from a sample, preferably a biological sample, comprising the steps of putting into contact the target compound with a capture molecule in order to allow a specific binding between the target compound with a capture molecule, the capture molecule being fixed upon a surface of a solid support according to an array comprising a density of at least 20 discrete regions per cm2, each of the discrete regions being fixed with one species of capture molecules, performing a reaction leading to a precipitate formed at the location of the binding, determining the possible presence of precipitate(s) in discrete region(s), and correlating the presence of the precipitate(s) at the discrete region(s) with the identification and/or a quantification of the target compound.
    Type: Grant
    Filed: May 19, 2000
    Date of Patent: January 22, 2008
    Assignee: Eppendorf Array Technologies (E.A.T.)
    Inventors: José Remacle, Joseph Demarteau, Nathalie Zammatteo, Isabelle Alexandre, Sandrine Hamels, Yves Houbion, Francoise De Longueville
  • Publication number: 20070298423
    Abstract: The present invention is related to a method for identifying and/or quantifying an organism or part of an organism in a sample by detecting a nucleotide sequence specific of said organism, among at least 4 other nucleotide sequences from other organisms or from parts of the organism.
    Type: Application
    Filed: March 30, 2007
    Publication date: December 27, 2007
    Applicant: Eppendorf Array Technologies SA (EAT)
    Inventors: Jose Remacle, Sandrine Hamels, Nathalie Zammatteo, Isabelle Alexandre, Francoise de Longueville
  • Publication number: 20070248990
    Abstract: The present invention concerns a new and simplified method for obtaining a polymer surface activated with a high density of aldehyde functions which are stable with time and ready to react covalently with amino groups present on a great number of different molecules used as capture probes according to a microarray.
    Type: Application
    Filed: April 19, 2007
    Publication date: October 25, 2007
    Applicant: EPPENDORF ARRAY TECHNOLOGIES S.A.
    Inventors: Jose Remacle, Sandrine Hamels, Heinz Koehn
  • Publication number: 20070117106
    Abstract: The present invention is related to an identification and/or quantification method of several organisms among many other ones possibly present in the analyzed sample having homologous sequence(s) by the determination of the genetic map of the organism. The method combines a limited number of amplifications of target sequence(s) using common primer pairs and the recording upon an array for the presence of single signals resulting from the binding between the capture sequence(s) and their corresponding target sequence(s) and correlating the presence of said detected target sequence(s) to the identification of some genetic specific sequence(s) of said (micro)organism(s) referred as genetic elements and from there to the identification of the organism. The method and device according to the invention allow the easy identification/detection of a sequence specific of an organism among other homologous sequence(s) and possibly its quantification.
    Type: Application
    Filed: May 16, 2006
    Publication date: May 24, 2007
    Inventors: Jose Remacle, Sandrine Hamels
  • Patent number: 7205104
    Abstract: A method for identifying or quantifying an organism by a detecting its nucleotide sequence among at least 4 other homologous sequences comprising amplifying nucleic acids from the organism to generate target nucleotide sequences to be detected; contacting the target nucleotide sequences with single stranded capture nucleotide sequences bound by a single predetermined link to an insoluble solid support and discriminating the binding of a target nucleotide sequence specific of an organism with a signal resulting from a hybridization by complementary base pairing between the target nucleotide sequence and its corresponding capture nucleotide sequence is disclosed. The capture nucleotide sequence is bound to the insoluble solid support at a specific location on an array having a density of at least 4 different bound single stranded capture nucleotide sequences/cm2. The location of the signal on the array allows identification or quantification of the organism.
    Type: Grant
    Filed: March 23, 2001
    Date of Patent: April 17, 2007
    Assignee: Eppendorf Array Technologies SA (EAT)
    Inventors: José Remacle, Sandrine Hamels, Nathalie Zammatteo, Laurence Lockman, Sophie Dufour, Isabelle Alexandre, Francoise De Longueville
  • Patent number: 7202026
    Abstract: The present invention is related to an identification and/or quantification method of a large number of biological organisms groups at different levels (family, genus, species) or part of those (possibly present in a biological sample) by a detection of their nucleotide sequence.
    Type: Grant
    Filed: January 23, 2002
    Date of Patent: April 10, 2007
    Assignee: Eppendorf Array Technologies SA (EAT)
    Inventors: José Remacle, Sandrine Hamels, Nathalie Zammatteo, Laurence Lockman, Sophie Dufour, Isabelle Alexandre, Francoise De Longueville
  • Publication number: 20060281112
    Abstract: The invention relates to a method for the design and/or the preparation of a polynucleotide capture molecule for detecting an amplicon having one strand serving as target to be detected and/or quantified after hybridization on said capture molecule, comprising the steps of: (a) selecting a primer pair defining the amplicon; (b) selecting a specific sequence of 10 to 100 nucleotides within the amplicon, such that said specific sequence defines two non-complementary ends of the amplicon; (c) defining the capture molecule having a capture portion that is complementary to the specific sequence selected in step b), and a spacer portion comprising at least 20 nucleotides; and (d) identifying among the two non-complementary ends of the amplicon a spacer end and a non-spacer end, respectively, such that the spacer end is non-complementary to the spacer portion of the capture molecule, and said spacer end exceeds said non-spacer end by at least 50 bases.
    Type: Application
    Filed: May 17, 2006
    Publication date: December 14, 2006
    Inventors: Jose Remacle, Sandrine Hamels
  • Publication number: 20060099619
    Abstract: The present invention relates to a new method for the detection, identification and/or quantification of multiple gene-specific mRNA or stRNA, respectively, the inducers of RNAi. In particular the present invention relates to a method for detecting the presence or change in concentration of mRNA in a cell, which change may be induced by environmental conditions.
    Type: Application
    Filed: October 4, 2005
    Publication date: May 11, 2006
    Inventors: Jose Remacle, Sandrine Hamels, Francoise Longueville
  • Publication number: 20050272044
    Abstract: The invention relates to a method and a kit for the specific identification and/or quantification of one or several among at least 7 organisms or parts thereof, in a biological sample being possibly contaminated by at least 4 other organisms, by detecting at least one nucleotide sequence specific of each of the organisms possibly present in said biological sample, wherein said nucleotide sequence is homologous with at least 4 other nucleotide sequences.
    Type: Application
    Filed: June 2, 2004
    Publication date: December 8, 2005
    Inventors: Jose Remacle, Sandrine Hamels, Sophie Burteau, Nathalie Zammatteo
  • Publication number: 20050118708
    Abstract: Cover of a hybridization chamber with a peripheral frame with filling and ventilation holes extending from the upper face to the lower face of the frame, a peripheral shoulder outside the filling and ventilation holes on the lower face of the frame, a cover wall arranged within the frame, flush with its lower face and downwardly offset relative to its upper face and which substantially consists of at least one resilient plastics material.
    Type: Application
    Filed: September 1, 2004
    Publication date: June 2, 2005
    Inventors: Martin Seippel, Sandrine Hamels, Christopher VanHuffel
  • Publication number: 20050037362
    Abstract: The present invention relates to a new method for the detection, identification and/or quantification of multiple gene-specific siRNA or stRNA, respectively, the inducers of RNAi. In particular the present invention relates to a method for detecting the presence or change in concentration of siRNA in a cell, which change may be induced by environmental conditions.
    Type: Application
    Filed: August 11, 2003
    Publication date: February 17, 2005
    Inventors: Jose Remacle, Sandrine Hamels, Francois de Longueville
  • Publication number: 20030198943
    Abstract: The present invention is related to an identification and/or quantification method of a large number of biological organisms groups at different levels (family, genus, species) or part of those (possibly present in a biological sample) by a detection of their nucleotide sequence.
    Type: Application
    Filed: January 23, 2002
    Publication date: October 23, 2003
    Inventors: Jose Remacle, Sandrine Hamels, Nathalie Zammatteo, Laurence Lockman, Sophie Dufour, Isabelle Alexandre, Francoise De Longueville