Patents by Inventor Sang-Jae Kim

Sang-Jae Kim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10039811
    Abstract: A peptide with anti-inflammatory activity, wherein the peptide comprises SEQ ID NO: 1, the peptide has above 80% homology of amino acid with above-mentioned sequence, or the peptide is the fragment of the above-mentioned peptides is described. An anti-inflammatory composition comprising the above mentioned peptides is described. According to the present invention, a peptide comprising a sequence of SEQ ID NO: 1 has outstanding efficacy in both suppressing inflammation and in prophylactic means. Therefore, the composition comprising the peptide of this invention can be used as anti-inflammatory pharmaceutical composition or as cosmetic composition, in turn, treating a variety of different types of inflammatory diseases.
    Type: Grant
    Filed: November 4, 2016
    Date of Patent: August 7, 2018
    Assignee: GemVax & KAEL Co., Ltd.
    Inventors: Sang Jae Kim, Kyung Hee Kim, Kyu-Yong Lee, Seong-Ho Koh, Hyun-Hee Park, Sung Jin Huh, Woo Jin Lee, Bum Joon Kim
  • Patent number: 10034922
    Abstract: A peptide having angiogenesis inhibition activity and pharmaceutical composition comprising thereof is described. More specifically, the application relates to the pharmaceutical composition for inhibiting angiogenesis comprising the peptide as a peptide derived from telomerase.
    Type: Grant
    Filed: November 21, 2014
    Date of Patent: July 31, 2018
    Assignee: GemVax & KAEL Co., Ltd.
    Inventor: Sang Jae Kim
  • Publication number: 20180207241
    Abstract: The present invention relates to a composition for inhibiting fibrosis and more specifically, to a composition for inhibiting fibrosis, wherein the composition is effective in inhibiting fibrosis of tissue cells by containing a peptide derived from telomerase. The peptide according to the present invention exhibits an effect of inhibiting the progression of various kinds of fibrosis, including fibrosis due to occurrence of cancer, fibrosis due to the administration of chemotherapy anticancer drugs, fibrosis due to the exposure to radiation, or progressive fibrosis of tissues, including a TGF-? signaling procedure, and thus can provide a composition for anti-fibrosis or inhibiting fibrosis and a method for treating diseases due to fibrosis.
    Type: Application
    Filed: March 15, 2018
    Publication date: July 26, 2018
    Applicant: GEMVAX & KAEL CO., LTD
    Inventor: Sang Jae KIM
  • Publication number: 20180208912
    Abstract: The present invention relates to a conjugate of cell penetrating peptide and an active ingredient; and its use. Specifically, a conjugate including a cell penetrating peptide which is a peptide comprising any one amino acid sequence of SEQ ID NO: 1 to SEQ ID NO: 156, a fragment of any one sequence of SEQ ID NO: 1 to SEQ ID NO: 156, or a peptide having above 80% homology with the above-mentioned sequence; and a composition comprising the same are disclosed.
    Type: Application
    Filed: January 12, 2018
    Publication date: July 26, 2018
    Inventor: Sang Jae KIM
  • Publication number: 20180134749
    Abstract: The present invention relates to a novel peptide and a composition including the same, and more particularly, to a novel peptide effective in anti-inflammation, anti-fibrosis, wound healing, and anti-cancer treatment, and a composition including the same. The novel peptide according to the present invention and the composition including the same exhibit an effect of alleviating, preventing, or treating inflammation, fibrosis, wounds, and symptoms of diseases such as cancer including these symptoms, and thus may provide a method of preventing or treating associated diseases.
    Type: Application
    Filed: May 25, 2016
    Publication date: May 17, 2018
    Inventor: Sang Jae KIM
  • Patent number: 9971192
    Abstract: A display panel includes a first substrate, a second substrate facing the first substrate, a liquid crystal layer interposed between the first substrate and the second substrate, a first transparent conductive pattern disposed on a surface of the first substrate and including a plurality of openings, and a first polarizing member combined with the first transparent conductive pattern. The display panel may reduce bending due to contraction of the first polarizing member including a drawn polarizing layer. Furthermore, static electricity generated in the second substrate may be discharged thereby improving reliability of a display device including the display panel.
    Type: Grant
    Filed: October 24, 2014
    Date of Patent: May 15, 2018
    Assignee: Samsung Display Co., Ltd.
    Inventors: Hyoung-Joo Lee, Kwang-Hyun Kim, Sang-Jae Kim, Gwan-Young Na, Seon-Ah Cho
  • Publication number: 20180103553
    Abstract: A flexible display device may include a display module including a first non-bending area and a first bending area adjacent to the first non-bending area, and a cushion layer disposed on a rear surface of the display module, wherein the cushion layer has a first density in the first non-bending area and a second density in the first bending area, and the first density is lower than the second density.
    Type: Application
    Filed: October 10, 2017
    Publication date: April 12, 2018
    Inventors: Youn Joon KIM, Sang Jae KIM, Se Bong KIM, Sol Bi LEE, Gyeong Ho JEONG
  • Patent number: 9937240
    Abstract: The present invention relates to a composition for inhibiting fibrosis and more specifically, to a composition for inhibiting fibrosis, wherein the composition is effective in inhibiting fibrosis of tissue cells by containing a peptide derived from telomerase. The peptide according to the present invention exhibits an effect of inhibiting the progression of various kinds of fibrosis, including fibrosis due to occurrence of cancer, fibrosis due to the administration of chemotherapy anticancer drugs, fibrosis due to the exposure to radiation, or progressive fibrosis of tissues, including a TGF-? signaling procedure, and thus can provide a composition for anti-fibrosis or inhibiting fibrosis and a method for treating diseases due to fibrosis.
    Type: Grant
    Filed: April 10, 2015
    Date of Patent: April 10, 2018
    Assignee: GemVax & KAEL Co., Ltd.
    Inventor: Sang Jae Kim
  • Patent number: 9907838
    Abstract: The present disclosure relates to a composition for treating and preventing an ischemic injury. More particularly, it relates to a composition containing a peptide derived from a telomerase, which is effective in treating and preventing an ischemic injury. The peptide according to the present disclosure, a peptide having 80% or more sequence identity with the amino acid sequence of the peptide or a peptide which is a fragment thereof, has a superior effect of treating and preventing an ischemic injury. Accordingly, a composition containing the peptide may be effectively used for an ischemic injury, particularly for an ischemic-reperfusion injury.
    Type: Grant
    Filed: April 18, 2014
    Date of Patent: March 6, 2018
    Assignee: GEMVAX & KAEL CO., LTD.
    Inventor: Sang Jae Kim
  • Patent number: 9907837
    Abstract: The present invention relates to composition for preventing or treating cachexia, and more specifically, to a composition for preventing or treating cachexia containing a peptide derived from a telomerase. The composition for preventing or treating cachexia, according to present invention, has the advantages of improving symptoms of cachexia, such as weight loss, anemia, edema, and loss of appetite, and has few side effects.
    Type: Grant
    Filed: May 10, 2013
    Date of Patent: March 6, 2018
    Assignee: GemVax & KAEL Co., Ltd.
    Inventor: Sang Jae Kim
  • Patent number: 9902945
    Abstract: The present invention relates to a conjugate of cell penetrating peptide and an active ingredient; and its use. Specifically, a conjugate including a cell penetrating peptide which is a peptide comprising any one amino acid sequence of SEQ ID NO: 1 to SEQ ID NO: 156, a fragment of any one sequence of SEQ ID NO: 1 to SEQ ID NO: 156, or a peptide having above 80% homology with the above-mentioned sequence; and a composition comprising the same are disclosed.
    Type: Grant
    Filed: September 17, 2013
    Date of Patent: February 27, 2018
    Assignee: GEMVAX & KAEL CO., LTD.
    Inventor: Sang Jae Kim
  • Publication number: 20180036384
    Abstract: The present invention relates to a pharmaceutical composition for preventing and treating hearing loss. More particularly, the present invention relates to a composition including a telomerase-derived peptide, the composition being effective in the treatment and prevention of hearing loss due to an ototoxic drug. A peptide having a sequence of SEQ ID NO: 1, a peptide having 80% or more sequence homology to the sequence, or a fragment thereof, according to the present invention, has an excellent effect in the treatment and prevention of hearing loss due to an ototoxic drug.
    Type: Application
    Filed: February 18, 2016
    Publication date: February 8, 2018
    Applicant: GemVax & KAEL CO. LTD.
    Inventor: Sang Jae KIM
  • Publication number: 20170360870
    Abstract: The present specification discloses a pharmaceutical composition for preventing or treating ophthalmopathy. More particularly, disclosed is a composition comprising a peptide derived from telomerase and being effective in treating and preventing ophthalmopathy. The disclosed peptide, a peptide having a sequence 80% identical to the sequence thereof, or a peptide as a fragment thereof is superiorly effective in treating ophthalmopathy.
    Type: Application
    Filed: December 22, 2015
    Publication date: December 21, 2017
    Applicant: Gemvax & KAEL CO., LTD.
    Inventor: Sang Jae KIM
  • Patent number: 9844584
    Abstract: Provided in the present invention is a peptide for preventing or treating sepsis. The peptide can improve symptoms of sepsis by inhibiting production of TNF, IL-1, and IL-6, which are cytokines that are related to sepsis, or can prevent or treat sepsis. Also disclosed are a pharmaceutical composition or a food composition containing the peptide as an active ingredient, a usage of the peptide for preventing or treating sepsis, and a kit comprising the peptide and instructions.
    Type: Grant
    Filed: May 10, 2013
    Date of Patent: December 19, 2017
    Assignee: GEMVAX & KAEL CO., LTD.
    Inventor: Sang Jae Kim
  • Publication number: 20170357120
    Abstract: A display device includes a first substrate and a second substrate which face each other, a first retarder which is disposed between the first substrate and the second substrate and is a positive C plate and a second retarder which is disposed on an outer side of the second substrate and is a negative biaxial film.
    Type: Application
    Filed: March 23, 2017
    Publication date: December 14, 2017
    Inventors: Kwang Hyun KIM, Sang Jae KIM, Yun JANG
  • Publication number: 20170336675
    Abstract: A display device, in which a plurality of pixels is defined, includes: a first insulating substrate; a polarizer disposed on a surface of the first insulating substrate; a second insulating substrate which faces the surface of the first insulating substrate; and a liquid crystal layer interposed between the polarizer and the second insulating substrate, where the liquid crystal layer includes liquid crystals and a dichroic dye.
    Type: Application
    Filed: February 14, 2017
    Publication date: November 23, 2017
    Inventors: Sang Jae KIM, Kwang Hyun KIM, Young Jin PARK, Yun JANG
  • Publication number: 20170327802
    Abstract: The present invention relates to a peptide with anti-inflammatory activity, wherein the peptide comprises any one amino acid sequence of SEQ ID NO: 1 to SEQ ID NO: 161, the peptide has above 80% homology of amino acid sequence with above-mentioned sequences, or the peptide is the fragment of the above-mentioned peptides. The present invention also relates to an inflammatory composition comprising the above mentioned peptides. According to the present invention, a peptide that has at least one amino acid sequence of SEQ ID NO: 1 to SEQ ID NO: 161 has outstanding efficacy in both suppressing inflammation and in prophylactic means. Therefore, the composition comprising the peptides of this invention can be used as anti-inflammatory pharmaceutical compositions or as cosmetic compositions, in turn, treating and preventing a variety of different types of inflammatory diseases.
    Type: Application
    Filed: July 31, 2017
    Publication date: November 16, 2017
    Inventors: Sang Jae KIM, Kyung Hee KIM, Kyu-Yong LEE, Seong-Ho KOH, Bum Joon KIM, Hyun-Hee PARK, Sung Jin HUH, Woo Jin LEE, Hwain JANG, Jung Soon HA
  • Patent number: 9791742
    Abstract: A liquid crystal display device includes a liquid crystal display panel which includes an array substrate including a pixel electrode, a gate line extending in a first direction and crossing the pixel electrode, and a data line extending in a second direction substantially perpendicular to the first direction, an opposing substrate including a common electrode in which a slit extending in the first direction and overlapping the gate line is defined, and a liquid crystal layer between the array substrate and the opposing substrate, and a light diffusion film which is disposed on the liquid crystal display panel and includes a plurality of low-refractive line members which respectively extends in the first direction and arranged in the second direction.
    Type: Grant
    Filed: August 8, 2014
    Date of Patent: October 17, 2017
    Assignee: SAMSUNG DISPLAY CO., LTD.
    Inventors: Seon-Ah Cho, Sang-Jae Kim, Hyoung-Joo Lee
  • Publication number: 20170275603
    Abstract: The present invention relates to a peptide with anti-inflammatory activity, wherein the peptide comprises any one amino acid sequence of SEQ ID NO:1 to SEQ ID NO: 161, the peptide has above 80% homology of amino acid sequence with above-mentioned sequences, or the peptide is the fragment of the above-mentioned peptides. The present invention also relates to an inflammatory composition comprising the above mentioned peptides. According to the present invention, a peptide that has at least one amino acid sequence of SEQ ID NO:1 to SEQ ID NO: 161 has outstanding efficacy in both suppressing inflammation and in prophylactic means. Therefore, the composition comprising the peptides of this invention can be used as anti-inflammatory pharmaceutical compositions or as cosmetic compositions, in turn, treating and preventing a variety of different types of inflammatory diseases.
    Type: Application
    Filed: April 5, 2017
    Publication date: September 28, 2017
    Inventors: Sang Jae KIM, Kyung Hee KIM, Kyu-Yong LEE, Seong-Ho KOH, Bum Joon KIM, Hyun-Hee PARK, Sung Jin HUH, Woo Jin LEE, Hwan JIANG, Jung Soon HA
  • Patent number: 9757473
    Abstract: A cell-penetrating peptide, a conjugate of the cell-penetrating peptide with an anticancer agent, and a composition comprising the conjugate is described. An effective means for transferring a cancer-specific anticancer agent can be provided by using the cell-penetrating peptide. More particularly, by preparing the conjugate of the present invention wherein the cell-penetrating peptide and the anticancer agent are combined, the application concentration of a conventional anticancer agent can be reduced and cancer specificity can be provided, and thus an effect of reducing side effects during the treatment process can be obtained.
    Type: Grant
    Filed: July 11, 2014
    Date of Patent: September 12, 2017
    Assignee: GemVax & KAEL Co., Ltd.
    Inventor: Sang Jae Kim