Abstract: The present invention relates to an inhibitor of SHP2, a pharmaceutical composition for preventing or treating a disease related to SHP2 comprising the same, a method for treating and preventing a disease using the same, and a use thereof. Accordingly, the present invention can effectively prevent or treat diseases related to SHP2.

Abstract: In the present specification, on the basis of the correlation between prospero homeobox protein 1 (PROX1) and telomerase reverse transcriptase (TERT), a composition for regulating expression of TERT, a method for screening a TERT expression regulator, a composition for diagnosing a TERT expression status, a diagnostic kit, a method for providing information for diagnosis, or a method for providing information for cancer diagnosis are disclosed. Specifically, in one aspect, the PROX1 of the present disclosure may bind to a TERT promoter, in particular a mutant TERT promoter in which base substitution occurs at the ?124 or ?146 bp position to regulate the expression of TERT, and the expression of TERT in non-hepatitis B virus-associated liver cancer can be inhibited specifically among liver cancers.

Abstract: An embodiment server includes a processor configured to collect driving data based on a driver driving propensity or a driving situation from a plurality of vehicles and to change information for determining an output torque suitable for each of the vehicles by analyzing the driving data and a communication device configured to transmit the changed information for determining the output torque to the vehicles by communicating with the vehicles.

Abstract: A service apparatus according to an embodiment of the present disclosure may include a user account management unit that manages accounts of a person with developmental disorder and a guardian of the person with developmental disorder; a training service information output unit that outputs training service information for improving the daily behavior of the person with developmental disorder; and a mode switching service unit that processes mode switching between a guardian mode and a person-with-developmental-disorder mode to output the training service information.

Abstract: An embodiment vehicle driving control apparatus includes a processor configured to determine an output torque of a driving source by using a driver driving propensity for each driver of a plurality of drivers or a driving situation based on a learning algorithm and a memory configured to store algorithms and data to be driven by the processor.

Abstract: An apparatus and a method for predicting a speed of a vehicle. The apparatus includes storage that stores past driving information of the vehicle. The apparatus also includes a controller that extracts feature information about a current state of the vehicle from the past driving information of the vehicle. The controller also generates a query corresponding to each target time point based on the feature information. The controller also determines forward information corresponding to each target time point by using each query. The controller also predicts the speed of the vehicle at each target time point based on the query corresponding to each target time point and the forward information corresponding to each target time point.

Abstract: Disclosed are a nanobarcode for controlling adhesion and polarization of macrophages and a method of controlling adhesion and polarization of macrophages by using nanobarcodes. The method of controlling adhesion and polarization of macrophages of the present invention may efficiently control adhesion and phenotypic polarization of macrophages in vivo or in vitro by tuning periodicity and sequences of ligand peptide (RGD) of a nanobarcode.

Abstract: Disclosed herein is an earphone module having a speaker capable of reproducing both high- and low-pitched sounds. In an earphone module according to the present invention, two coils and terminal members configured to be electrically connected to the two coils are provided, the two coils and the terminal members are assembled by electrically connecting the two coils and the terminal members to each other, and then the terminal members are connected to an external input circuit through the exposure window of a housing. Accordingly, the manufacturing operation is facilitated and the defect rate is reduced, so that the mass productivity is improved.

Abstract: The present disclosure relates to an organic electroluminescent compound and an organic electroluminescent device comprising the same. By comprising the compound according to the present disclosure, it is possible to produce an organic electroluminescent device having improved driving voltage, power efficiency, and/or lifetime properties compared to the conventional organic electroluminescent devices.

Abstract: A semiconductor manufacturing equipment may include a process chamber for treating a substrate; a front-end module including a first transfer robot, wherein the first transfer robot may be configured to transport the substrate received in a container; a transfer chamber between the front-end module and the process chamber, wherein the transfer chamber may be configured to load or unload the substrate into or out of the process chamber; and a cassette capable of receiving a replaceable component capable of being used in the process chamber. The front-end module may include a seat plate configured to move in a sliding manner so as to retract or extend into or from the front-end module. The cassette may be configured to be loaded into the front-end module while the cassette is seated on the seat plate.

Abstract: The present invention relates to a method for producing a polyimide powder, particularly to a method for producing a polyimide powder, which includes a) preparing a dispersion by dispersing a dianhydride and a diamine in distilled water; and b) introducing the dispersion of step a) into a reactor and conducting the reaction at a stirring speed of 300 rpm or more under temperature and pressure conditions. In the present invention, it is possible to improve physical properties and control the particle size and dispersibility without additional processes by using water-based polymerization and controlling the stirring speed in the production process.

Abstract: Disclosed are display panels and display devices. The display panel comprises a base layer which includes a first region and a second region having a first sub-region and a second sub-region, first pixels in the first region, and second pixels in the first sub-region. Each of the first and second pixels includes a pixel electrode, an emission layer on the pixel electrode, and a common electrode on the emission layer. The pixel electrode is shifted relative to the emission layer in a direction away from the second sub-region.

Abstract: A camera module includes: a first substrate on which an image sensor configured to convert an optical signal incident through a lens module into an electrical signal is disposed and a first connection terminal is disposed; a second substrate spaced apart from the first substrate and including a second connection terminal formed in a position facing the first connection terminal; and a terminal connector electrically connecting the first connection terminal and the second connection terminal to each other and configured to maintain a preset distance between the first substrate and the second substrate. In the camera module, the terminal connector includes: a connecting member including a first connection portion, a second connection portion, and a deformable portion; and a support member configured to maintain the preset distance between the first substrate and the second substrate.

Abstract: Disclosed are an apparatus for distributing power of an electric vehicle and a method thereof capable of optimally improving the energy consumption efficiency of the electric vehicle by predicting a vehicle speed for a predetermined time using a learned vehicle speed prediction model, determining wheel power based on the vehicle speed, and distributing the wheel power to a front wheel drive motor and a rear wheel drive motor. The apparatus includes a storage that stores a vehicle speed prediction model in which learning is completed, and a controller that predicts a vehicle speed for a preset time using the vehicle speed prediction model, determines wheel power based on the vehicle speed, and distributes the wheel power to a front wheel drive motor and a rear wheel drive motor.

Abstract: A file protection method of a computer apparatus including a processor, the method including extracting classes from an executable file of a package file, classifying the classes into class groups, adding a loading code to a first class group among the class groups, the loading code configured to cause sequential loading of the class groups to a memory in a random loading order in response to execution of the package file, adding an integrity code to a second class group among the class groups, the integrity code configured to verify an integrity of a corresponding class group among the class groups or a previous class group among the class groups, the previous class group including the loading code configured to cause the corresponding class group to load, and regenerating the package file using the class groups after the adding the loading code and the adding the integrity code.

Abstract: The present invention relates to technology capable of labeling a certain site of an antibody with a certain number of chemical functional groups or cargo moieties. The present invention may provide an antibody product having high uniformity. The present invention may provide an antibody product whose antibody functions are not degraded. That is, the present invention may provide an antibody product whose antibody binding affinity and half-life are not degraded. The present invention is of great significance as being the first technology allowing site-specific labeling of an antibody without any complicated processes.

Abstract: Disclosed are a cobalt-tungsten alloy and a method of fabricating the same. More particularly, cobalt-tungsten alloy nanowires according to an embodiment are formed using an electroplating method, a grain structure of the cobalt-tungsten alloy nanowires is controlled according to the content of tungsten, and the electrical resistivity of the cobalt-tungsten alloy nanowires can be reduced through annealing.

Abstract: A coil electronic component is provided, the coil electronic component including a body having a laminate structure formed of a plurality of conductor patterns disposed therein, and including an insulating layer disposed between the plurality of conductor patterns, and an external electrode disposed externally of the body. Portions of the plurality of conductor patterns include a coil pattern and a lead-out pattern connecting the coil pattern and the external electrode, the lead-out pattern includes a first metal layer and a second metal layer disposed on the first metal layer, and a pore density of the first metal layer is higher than a pore density of the second metal layer.

Abstract: Disclosed herein is an earphone module having a speaker capable of reproducing both high- and low-pitched sounds. In an earphone module according to the present invention, two coils and terminal members configured to be electrically connected to the two coils are provided, the two coils and the terminal members are assembled by electrically connecting the two coils and the terminal members to each other, and then the terminal members are connected to an external input circuit through the exposure window of a housing. Accordingly, the manufacturing operation is facilitated and the defect rate is reduced, so that the mass productivity is improved.

Abstract: A vertical-cavity surface-emitting laser (VCSEL) including a substrate including a plurality of emitters forming an array region, a lower mirror, an upper mirror, an active layer interposed between the lower mirror and the upper mirror, an aperture forming layer interposed between the upper mirror and the active layer and including an oxidation region and a window region, a connector disposed on the upper mirror, a plurality of oxidation holes passing through the upper mirror and the aperture forming layer, an upper insulation layer covering the plurality of oxidation holes, and a pad electrically connected to the connector, in which at least a portion of the connector is disposed in the plurality of oxidation holes, and the plurality of emitters is disposed in substantially a honeycomb shape on the substrate.