Patents by Inventor Sang Jun Ha
Sang Jun Ha has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240153831Abstract: An apparatus and method for measuring air currents on the surface of a substrate, which can accurately measure the magnitude and direction of air currents on the surface of a wafer with wafer-type air current measurement sensors, are provided. The apparatus includes: a first air current measurement module measuring a magnitude of air currents on a surface of a first substrate, which is processed in accordance with a semiconductor manufacturing process; a second air current measurement module measuring a movement direction of the air currents; and a power module supplying power to the first and second air current measurement modules, wherein the first air current measurement module, the second air current measurement module, and the power module are mounted on a second substrate, which has the same shape as the first substrate.Type: ApplicationFiled: October 19, 2023Publication date: May 9, 2024Inventors: Yong Jun SEO, Su Jin CHAE, Sang Hyun SON, Sang Min HA, Young Sik BANG, Jeong Mo HWANG, Dong Ok AHN
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Patent number: 11919303Abstract: Provided is a jetting driver that can be used for various types of heads with minimal changes. The jetting driver includes: an image board receiving raw image data and generating image data by transforming the raw image data into a form suitable for a type of heads used; and an interface board physically separated from the image board, receiving the image data, and transmitting the image data to the heads through a plurality of channels.Type: GrantFiled: May 1, 2022Date of Patent: March 5, 2024Assignee: SEMES CO., LTD.Inventors: Sang Min Ha, Sang Hyun Son, Young Joo Seo, Hyeong Jun Cho, Jae Hong Kim
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Patent number: 11891445Abstract: Provided is an anti-B7-H3 antibody specifically recognizing a B7-H3, which can be usefully as a cancer therapeutic agent, as having an inhibitory activity of an immune checkpoint which induces antibody-dependent cell-mediated cytotoxicity and T cell activation inhibited by B7-H3. In particular, the antibody having the inhibitory activity of an immune checkpoint can be used in combination with other immunoantibody therapeutic agents. In addition, it can be usefully used for cancer targeting treatment including detection of various cancers expressing B7-H3 through specific binding to B7-H3, and drug delivery to specific cancer, etc.Type: GrantFiled: May 24, 2019Date of Patent: February 6, 2024Assignee: ABL BIO INC.Inventors: Kyeongsu Park, Yangsoon Lee, Hyejin Chung, Uijung Jung, Yong-Gyu Son, Sang-Jun Ha, Myeong Joon Kim, Eunyoung Park, Kyungjin Park, Eunsil Sung, Yeunju Kim, Jinhyung Ahn, Byungje Sung, Daehae Song, Youngdon Pak
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Patent number: 11826324Abstract: Provided are a pharmaceutical composition for preventing or treating inflammatory disease, autoimmune disease, graft rejection responses, or combinations thereof, the pharmaceutical composition including a compound represented by Formula 1, or a stereoisomer, derivative, solvate, or pharmaceutically acceptable salt thereof, and a method using the pharmaceutical composition. The pharmaceutical composition and the method can be used to effectively prevent or treat inflammatory disease, autoimmune disease, graft rejection responses, or combinations thereof.Type: GrantFiled: December 18, 2020Date of Patent: November 28, 2023Assignees: INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY, IMMUNOMET THERAPEUTICS INC.Inventors: Jungsik Song, Beom Seok Kim, Sang Jun Ha, Ji Min Son
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Publication number: 20230235376Abstract: Provided are a method for predicting a treatment response to cancer immunotherapy, the method comprising a step of evaluating, from feces isolated from a patient, the enrichment of a strain of the order TANB77 according to GTDB phylogenetic classification or taxa belonging to the order TANB77, and a step of predicting a treatment response of the patient to cancer immunotherapy on the basis of the enrichment of the order TANB77 or the taxa; a probiotics composition for improving a treatment response; a fecal microbiota transplantation composition; and a method for screening for candidate prebiotics by using same.Type: ApplicationFiled: June 30, 2021Publication date: July 27, 2023Applicant: INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITYInventors: In Suk LEE, Sang Jun HA, Chan Yeong KIM, Hye Ryun KIM, Beung Chul AHN
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Publication number: 20210325394Abstract: Provided in the present disclosure are a method for providing information on a therapeutic reaction of cancer immunotherapy and a kit using same for providing information, the method comprising the steps of: measuring respective expression levels of PD-L1 and PVR in a biological sample isolated from a subject; and evaluating the therapeutic reaction of cancer immunotherapy for the subject on the basis of the measured expression levels of PD-L1 and PVR.Type: ApplicationFiled: August 28, 2019Publication date: October 21, 2021Applicants: INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY, REPUBLIC OF KOREA (MINISTER OF FOOD AND DRUG SAFETY)Inventors: Sang Jun HA, Hye Ryun KIM, Hyo Sup SHIM, Bo Ryeong LEE, Jung Yeon YI, Dae Hee HWANG
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Patent number: 11029417Abstract: The present invention relates to a radioactivity measurement method and a radioactivity measurement system using data expansion. A radioactivity measurement method using data expansion according to the present invention comprises the steps of: measuring radioactivity while performing energy scanning and temporal scanning; preparing a database from a time-energy-related data set obtained in result of the scanning; expanding the database by means of random distribution fitting; and obtaining a radioactivity measurement value of desired time from the database.Type: GrantFiled: January 2, 2018Date of Patent: June 8, 2021Assignee: KOREA HYDRO & NUCLEAR POWER CO., LTDInventors: Seung Chan Lee, Je Joong Sung, Duk Joo Yoon, Sang Jun Ha
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Patent number: 11027224Abstract: A device for collecting air into an air collecting pipe through a hole having a certain size includes a diaphragm check valve having elasticity. The diaphragm check valve is opened due to a change in the pressure in the vicinity of an air layer during generation of air when gas accumulation occurs in a safety related system pipe of a power plant or in a general pipe.Type: GrantFiled: February 24, 2016Date of Patent: June 8, 2021Assignee: KOREA HYDRO & NUCLEAR POWER CO., LTD.Inventors: Seung Chan Lee, Duk Joo Yoon, Sang Jun Ha
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Publication number: 20210113497Abstract: Provided are a pharmaceutical composition for preventing or treating inflammatory disease, autoimmune disease, graft rejection responses, or combinations thereof, the pharmaceutical composition including a compound represented by Formula 1, or a stereoisomer, derivative, solvate, or pharmaceutically acceptable salt thereof, and a method using the pharmaceutical composition. The pharmaceutical composition and the method can be used to effectively prevent or treat inflammatory disease, autoimmune disease, graft rejection responses, or combinations thereof.Type: ApplicationFiled: December 18, 2020Publication date: April 22, 2021Applicants: INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY, IMMUNOMET THERAPEUTICS INC.Inventors: Jungsik SONG, Beom Seok KIM, Sang Jun HA, Ji Min SON
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Publication number: 20200223926Abstract: PD-1 antagonists are disclosed that can be used to reduce the expression or activity of PD-1 in a subject. An immune response specific to an infectious agent or to tumor cells can be enhanced using these PD-1 antagonists in conjunction with an antigen from the infectious agent or tumor. Thus, subjects with infections, such as persistent infections can be treated using PD-1 antagonists. In addition, subjects with tumors can be treated using the PD-1 antagonists. In several examples, subjects can be treated by transplanting a therapeutically effective amount of activated T cells that recognize an antigen of interest and by administering a therapeutically effective amount of a PD-1 antagonist.Type: ApplicationFiled: August 23, 2019Publication date: July 16, 2020Applicants: Emory University, Dana-Farber Cancer Institute, Inc., President and Fellows of Harvard CollegeInventors: Rafi Ahmed, Rama Amara, Gordon Freeman, Arlene Sharpe, Daniel Barber, E. John Wherry, Sang-Jun Ha
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Publication number: 20200038347Abstract: Provided are a pharmaceutical composition for preventing or treating inflammatory disease, autoimmune disease, graft rejection responses, or combinations thereof, the pharmaceutical composition including a compound represented by Formula 1, or a stereoisomer, derivative, solvate, or pharmaceutically acceptable salt thereof, and a method using the pharmaceutical composition. The pharmaceutical composition and the method can be used to effectively prevent or treat inflammatory disease, autoimmune disease, graft rejection responses, or combinations thereof.Type: ApplicationFiled: January 23, 2018Publication date: February 6, 2020Applicants: INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY, IMMUNOMET THERAPEUTICS INC.Inventors: Jungsik SONG, Beom Seok KIM, Sang Jun HA, Ji Min SON
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Publication number: 20190331804Abstract: The present invention relates to a radioactivity measurement method and a radioactivity measurement system using data expansion. A radioactivity measurement method using data expansion according to the present invention comprises the steps of: measuring radioactivity while performing energy scanning and temporal scanning; preparing a database from a time-energy-related data set obtained in result of the scanning; expanding the database by means of random distribution fitting; and obtaining a radioactivity measurement value of desired time from the database.Type: ApplicationFiled: January 2, 2018Publication date: October 31, 2019Inventors: Seung Chan LEE, Je Joong SUNG, Duk Joo YOON, Sang Jun HA
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Patent number: 10416022Abstract: The present invention relates to an apparatus and method for monitoring the water level within a pipe. The present specification discloses a method for monitoring the water level in a pipe, comprising the steps of: transmitting ultrasonic waves generated at a plurality of ultrasonic transducers, which are spaced apart from each other in the outside of the pipe, to the inside of the pipe via a solid contact medium; checking whether echoes corresponding to respective ultrasonic waves are present; and determining the water level on the basis of the presence of the echoes corresponding to the respective ultrasonic waves. The present invention can simply and conveniently install water level monitoring equipment within a pipe on a long term basis using a nondestructive method.Type: GrantFiled: October 31, 2014Date of Patent: September 17, 2019Assignee: KOREA HYDRO & NUCLEAR POWER CO., LTDInventors: Seung Chan Lee, Duk Joo Yoon, Sang Jun Ha
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Publication number: 20190031758Abstract: PD-1 antagonists are disclosed that can be used to reduce the expression or activity of PD-1 in a subject. An immune response specific to an infectious agent or to tumor cells can be enhanced using these PD-1 antagonists in conjunction with an antigen from the infectious agent or tumor. Thus, subjects with infections, such as persistent infections can be treated using PD-1 antagonists. In addition, subjects with tumors can be treated using the PD-1 antagonists. In several examples, subjects can be treated by transplanting a therapeutically effective amount of activated T cells that recognize an antigen of interest and by administering a therapeutically effective amount of a PD-1 antagonist.Type: ApplicationFiled: February 15, 2018Publication date: January 31, 2019Applicants: Emory University, Dana-Farber Cancer Institute, Inc., President and Fellows of Harvard CollegeInventors: Rafi Ahmed, Rama Amara, Gordon Freeman, Arlene Sharpe, Daniel Barber, E. John Wherry, Sang-Jun Ha
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Publication number: 20180369719Abstract: A device for collecting air into an air collecting pipe through a hole having a certain size includes a diaphragm check valve having elasticity. The diaphragm check valve is opened due to a change in the pressure in the vicinity of an air layer during generation of air when gas accumulation occurs in a safety related system pipe of a power plant or in a general pipe.Type: ApplicationFiled: February 24, 2016Publication date: December 27, 2018Inventors: Seung Chan LEE, Duk Joo YOON, Sang Jun HA
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Publication number: 20170314984Abstract: The present invention relates to an apparatus and method for monitoring the water level within a pipe. The present specification discloses a method for monitoring the water level in a pipe, comprising the steps of: transmitting ultrasonic waves generated at a plurality of ultrasonic transducers, which are spaced apart from each other in the outside of the pipe, to the inside of the pipe via a solid contact medium; checking whether echoes corresponding to respective ultrasonic waves are present; and determining the water level on the basis of the presence of the echoes corresponding to the respective ultrasonic waves. The present invention can simply and conveniently install water level monitoring equipment within a pipe on a long term basis using a nondestructive method.Type: ApplicationFiled: October 31, 2014Publication date: November 2, 2017Inventors: Seung Chan Lee, Duk Joo Yoon, Sang Jun Ha
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Patent number: 7910564Abstract: The present invention relates to the IL-12p40 subunit mutant gene which can produce IL-12 (interleukin 12) of human and mouse origin with high activity, the expression vector including above mutant gene and the use of them to DNA vaccine adjuvant. Particularly, it relates to IL-12p40 mutant gene which inhibits the secretion of IL-12p40 but normally secretes active IL- 12p70 by making mutation at Asn-222 (human) or Asn- 220 (mouse) amino acid of IL-12p40, which acts as a competitive inhibitor of active form of IL-12, IL-12p70. Therefore, the IL-12p40 mutant gene of the present invention can be useful for DNA vaccination and gene therapy against various diseases, for example, AIDS, hepatitis C or hepatitis B, cancer, influenza, tuberculosis and malaria, which essentially require cellular immune responses for their therapy.Type: GrantFiled: August 2, 2007Date of Patent: March 22, 2011Assignee: Genexine Co., Ltd.Inventors: Young Chul Sung, Sung Hee Lee, Sang Jun Ha, Man Ki Song, Jun Chang
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Patent number: 7253151Abstract: The present invention relates to the IL-12p40 subunit mutant gene which can produce IL-12(interleukin 12) of human and mouse origin with high activity, the expression vector including above mutant gene and the use of them to DNA vaccine adjuvant. Particularly, it relates to IL-12p40 mutant gene which inhibits the secretion of IL-12p40 but normally secretes active IL-12p70 by making mutation at Asn-222(human) or Asn-220(mouse) amino acid of IL-12p40, which acts as a competitive inhibitor of active form of IL-12, IL-12p70. Therefore, the IL-12p40 mutant gene of the present invention can be useful for DNA vaccination and gene therapy against various diseases, for example, AIDS, hepatitis C or hepatitis B, cancer, influenza, tuberculosis and malaria, which essentially require cellular immune responses for their therapy.Type: GrantFiled: March 15, 2001Date of Patent: August 7, 2007Assignee: Genexine Co., Ltd.Inventors: Young Chul Sung, Sung Hee Lee, Sang Jun Ha, Man Ki Song, Jun Chang
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Publication number: 20040023332Abstract: The present invention relates to the IL-12p40 subunit mutant gene which can produce IL-12 (interleukin 12) of human and mouse origin with high activity, the expression vector including above mutant gene and the use of them to DNA vaccine adjuvant. Particularly, it relates to IL-12p40 mutant gene which inhibits the secretion of IL-12p40 but normally secretes active IL-12p70 by making mutation at Asn-222 (human) or Asn-220 (mouse) amino acid of IL-12p40, which acts as a competitive inhibitor of active form of IL-12, IL-12p70. Therefore, the IL-12p40 mutant gene of the present invention can be useful for DNA vaccination and gene therapy against various diseases, for example, AIDS, hepatitis C or hepatitis B, cancer, influenza, tuberculosis and malaria, which essentially require cellular immune responses for their therapy.Type: ApplicationFiled: April 29, 2003Publication date: February 5, 2004Inventors: Young Chul Sung, Sung Hee Lee, Sang Jun Ha, Man Ki Song, Jun Chang