Abstract: The present disclosure relates to a Mitochondria-Associated endoplasmic reticulum Membrane (MAM)-specific fluorescence calcium sensor and the use thereof. The present disclosure can surmount the limitations of a conventional technique in that verification of calcium migration through MAM requires separate measurements of calcium ion concentrations within ER and mitochondria and situational explanations of the phenomena, and can directly measure concentrations in the paths through which calcium ions move to exclude influences on calcium ion changes through numerous different calcium ion channels existing in mitochondria, thereby providing a convenient and accurate MAM-specific calcium ion sensor.

Abstract: A thermoplastic resin composition according to the present invention comprises: about 100 parts by weight of a polycarbonate resin; about 5 to about 15 parts by weight of a first rubber-modified vinyl-based graft copolymer in which a monomer mixture is graft-polymerized to a rubber polymer, the monomer mixture containing an aromatic vinyl-based monomer and a cyanovinyl-based monomer; about 2 to about 8 parts by weight of a second rubber-modified vinyl-based graft copolymer in which an alkyl (meth)acrylate-based monomer is graft-polymerized to a rubber polymer; about 0.5 to about 2 parts by weight of a siloxane copolyester; about 17 to about 40 parts by weight of talc; and about 13 to about 23 parts by weight of a phosphorus-based flame retardant, wherein the weight ratio of the first rubber-modified vinyl-based graft copolymer to the second rubber-modified vinyl-based graft copolymer is about 1:0.15 to about 1:0.

Abstract: An embodiment of the present disclosure provides a manipulator for a finishing work, including: a base; an arm comprising a plurality of links, a plurality of joints connecting the plurality of links, and a plurality of actuators generating rotation of at least some of the plurality of joints; and a processor determining a driving torque of each of the plurality of actuators considering a self-weight effect of the manipulator and controlling the plurality of actuators based on the determined driving torque.

Abstract: The present disclosure relates to a Mitochondria-Associated endoplasmic reticulum Membrane (MAM)-specific fluorescence calcium sensor and the use thereof. The present disclosure can surmount the limitations of a conventional technique in that verification of calcium migration through MAM requires separate measurements of calcium ion concentrations within ER and mitochondria and situational explanations of the phenomena, and can directly measure concentrations in the paths through which calcium ions move to exclude influences on calcium ion changes through numerous different calcium ion channels existing in mitochondria, thereby providing a convenient and accurate MAM-specific calcium ion sensor.

Abstract: Provided herein are a pharmaceutical composition for preventing or treating a stress-related disease, which includes the DISC1 protein or a gene encoding the DISC protein, and a method of screening a material for preventing or treating the stress-related disease. As a result of studying the association between DISC1 and psychological stress, the inventors of the present disclosure verified the function of DISC1 in downregulating ER-mitochondria Ca2+ transfer induced by stress hormone-mediated oxidative stress by competitively inhibiting the binding of IP3 to inositol 1,4,5-trisphosphate (IP3) receptor type1 (IP3R1) by binding to the IP3R1 at the MAM, and an acting site of DISC1, and this provides a model of intracellular calcium response to physiological stress, and DISC1, a stress modulating substance, and the model may be usefully used in related fields for the prevention and treatment of stress-related diseases.

Abstract: A lighting system and a selective retro-reflection apparatus are provided. The lighting system includes a lamp, a reflector configured to reflect light emitted by the lamp, a projection lens configured to emit the reflected light of the reflector in a predetermined direction, and a selective shield apparatus disposed between the projection lens and the reflector and provided on a path of light directed upward among the light reflected from the reflector to selectively shield the light directed upward, wherein the selective shield apparatus includes a panel and a selective shield portion supported by the panel, positions of the panel and the selective shield portion are fixed, and a state in which the selective shield portion transmits the light is changed according to whether power is supplied.

Abstract: A polycarbonate resin composition and a molded product produced from the same includes (a) polycarbonate resin; (b) polycarbonate-polysiloxane copolymer; (c) aromatic copolyester resin; and (d) glass fiber.

Abstract: Methods of manufacturing a volumetric continuous gradient complex dielectric element with drop-on-demand techniques, such as inkjet printing, by calculating spatial placement of nanocomposite-ink droplets are disclosed. The methods comprise determining or having a multi-dimensional gradient profile representing a volumetric gradient complex dielectric element. Providing or having a plurality of nanocomposite-inks, at least one of the nanocomposite-inks having a curable organic-matrix and a concentration of nanoparticles dispersed within to print the volumetric continuous gradient complex dielectric device. A print mask is determined in one-, two-, or three-dimensions that reconstructs the multi-dimensional gradient profile as a discretized pattern based on the material properties of the plurality of nanocomposite-inks and properties of a printing apparatus with a plurality of printheads.

Abstract: There is provided a pipeline inspection device including: a body part contacting a pipeline and accommodating the pipeline; a coupling part coupled to the body part to enclose the pipeline; and a sensor part including a sensor on at least one of one side of the body part and one side of the coupling part which are in contact with the pipeline to inspect an internal state of the pipeline. The pipeline inspection device according to exemplary embodiments is capable of inspecting pipelines without increasing a gap between the pipelines even in a case in which the gap therebetween is relatively narrow, and is capable of readily and rapidly inspecting a large area of pipelines.

Abstract: Methods of manufacturing a volumetric continuous gradient complex dielectric element with drop-on-demand techniques, such as inkjet printing, by calculating spatial placement of nanocomposite-ink droplets are disclosed. The methods comprise determining or having a multi-dimensional gradient profile representing a volumetric gradient complex dielectric element. Providing or having a plurality of nanocomposite-inks, at least one of the nanocomposite-inks having a curable organic-matrix and a concentration of nanoparticles dispersed within to print the volumetric continuous gradient complex dielectric device. A print mask is determined in one-, two-, or three-dimensions that reconstructs the multi-dimensional gradient profile as a discretized pattern based on the material properties of the plurality of nanocomposite-inks and properties of a printing apparatus with a plurality of printheads.

Abstract: Methods of manufacturing a volumetric continuous gradient complex dielectric element with drop-on-demand techniques, such as inkjet printing, by calculating spatial placement of nanocomposite-ink droplets are disclosed. The methods comprise determining or having a multi-dimensional gradient profile representing a volumetric gradient complex dielectric element. Providing or having a plurality of nanocomposite-inks, at least one of the nanocomposite-inks having a curable organic-matrix and a concentration of nanoparticles dispersed within to print the volumetric continuous gradient complex dielectric device. A print mask is determined in one-, two-, or three-dimensions that reconstructs the multi-dimensional gradient profile as a discretized pattern based on the material properties of the plurality of nanocomposite-inks and properties of a printing apparatus.

Abstract: In a structure which forms an upper structure and a lower structure divided by an anti-vibration pad for vibration isolation therein, since the concavo-convex type shear key is formed using the precast concrete shear-key block, the construction can be precisely performed according to the predetermined standard. Therefore, a vibration isolation structure using a precast concrete shear-key block and an anti-vibration pad which are capable of effectively blocking vibration and noise, and a constructing method thereof are provided.

Abstract: Devices and methods for maintaining the brightness of laser emitter bar outputs having multiple emitters for coupling and other applications. In some embodiments, at least one brightness enhancement optic may be used in combination with a beam reformatting optic.

Abstract: A lighting system and a selective retro-reflection apparatus are provided. The lighting system includes a lamp, a reflector configured to reflect light emitted by the lamp, a projection lens configured to emit the reflected light of the reflector in a predetermined direction, and a selective shield apparatus disposed between the projection lens and the reflector and provided on a path of light directed upward among the light reflected from the reflector to selectively shield the light directed upward, wherein the selective shield apparatus includes a panel and a selective shield portion supported by the panel, positions of the panel and the selective shield portion are fixed, and a state in which the selective shield portion transmits the light is changed according to whether power is supplied.

Abstract: A polycarbonate resin composition and a molded product produced from the same includes (a) polycarbonate resin; (b) polycarbonate-polysiloxane copolymer; (c) aromatic copolyester resin; and (d) glass fiber.

Abstract: Optical systems and components thereof are disclosed which may be used for efficiently coupling laser energy into an optical conduit while maintaining a homogenous beam output from the optical conduit. Some embodiments are directed more specifically to far field beam homogenization of optical fiber coupled radiation.

Abstract: There is provided a pipeline inspection device including: a body part contacting a pipeline and accommodating the pipeline; a coupling part coupled to the body part to enclose the pipeline; and a sensor part including a sensor on at least one of one side of the body part and one side of the coupling part which are in contact with the pipeline to inspect an internal state of the pipeline. The pipeline inspection device according to exemplary embodiments is capable of inspecting pipelines without increasing a gap between the pipelines even in a case in which the gap therebetween is relatively narrow, and is capable of readily and rapidly inspecting a large area of pipelines.

Abstract: In a structure which forms an upper structure and a lower structure divided by an anti-vibration pad for vibration isolation therein, since the concavo-convex type shear key is formed using the precast concrete shear-key block, the construction can be precisely performed according to the predetermined standard. Therefore, a vibration isolation structure using a precast concrete shear-key block and an anti-vibration pad which are capable of effectively blocking vibration and noise, and a constructing method thereof are provided.

Abstract: A polycarbonate resin composition can have improved transparency and scratch resistance of the present invention and comprises about 10 to about 99% by weight of polycarbonate resin (A); and about 1 to about 90% by weight of acrylic copolymer with ultra-low molecular weight and high refractive index (B). The resin composition of the present invention can further comprise acrylic resin (C). The acrylic copolymer with ultra-low molecular weight and high refractive index (B) can have a refractive index of about 1.495 to about 1.590 and a weight average molecular weight of about 3,000 to about 40,000 g/mol.

Abstract: Devices and methods for maintaining the brightness of laser emitter bar outputs having multiple emitters for coupling and other applications. In some embodiments, at least one brightness enhancement optic may be used in combination with a beam reformatting optic.