Patents by Inventor Sang-Moo Lim

Sang-Moo Lim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230029695
    Abstract: The present invention relates to a radiopharmaceutical distribution image generation system and method using deep learning and, more specifically, to a radiopharmaceutical distribution image generation system and method using deep learning, wherein dynamic medical images collected from multiple patients and a time-radiation dose distribution curve for each organ can be learnt through a deep learning network and a spatial distribution image of a radiopharmaceutical can be generated from a static medical image acquired from a specific patient. According to the present invention, even when a medical image is acquired only for a specific time after a radiopharmaceutical is injected into a patient, a spatial distribution image of the radiopharmaceutical can be acquired across the entire time by usin g the deep learning network, and quantitative analysis of the radiopharmaceutical can be performed by calculating a time-radiation dose distribution curve on the basis thereof.
    Type: Application
    Filed: July 2, 2020
    Publication date: February 2, 2023
    Inventors: Sang Keun WOO, Sang Moo LIM, Kyo Chul LEE, Wook KIM
  • Patent number: 11476012
    Abstract: The disclosure provide an apparatus for producing a nuclide by using a liquid target which can perform the nuclear reaction process and can discharge the radioactive gas such as Radon within the vial. As described above, an apparatus for producing a nuclide by using a liquid target according to the present disclosure can minimize quantitative loss of a reactant by performing the nuclear reaction process using a target of a liquefied state and reusing a liquefied target on which the nuclear reaction process has not been performed, and can improve safety by enabling the radioactive gas generated to be disposed.
    Type: Grant
    Filed: June 30, 2020
    Date of Patent: October 18, 2022
    Assignee: KOREA INSTITUTE OF RADIOLOGICAL & MEDICAL SCIENCES
    Inventors: Se Young Oh, Sang Moo Lim, Kyo Chul Lee, Joo Hyun Kang
  • Patent number: 11424047
    Abstract: A method of producing actinium by using liquefied radium includes producing Ac-225 using Ra-226 of a liquefied state, moving the produced Ac-225 in a liquefied state after Ac-225 is produced, and separating Ac-225 and reusing Ra-226. As a result, a nuclear reaction process of Ac-225 may be performed and loss of Ra-226 may be minimized. Further, such a method may improve safety by including a radon collection unit which is capable of discharging and isolating radon produced from Ra-226, thereby preventing radiation exposure due to radon.
    Type: Grant
    Filed: June 30, 2020
    Date of Patent: August 23, 2022
    Assignee: KOREA INSTITUTE OF RADIOLOGICAL & MEDICAL SCIENCES
    Inventors: Se Young Oh, Sang Moo Lim, Kyo Chul Lee, Joo Hyun Kang
  • Publication number: 20210027904
    Abstract: The disclosure provide an apparatus for producing a nuclide by using a liquid target which can perform the nuclear reaction process and can discharge the radioactive gas such as Radon within the vial. As described above, an apparatus for producing a nuclide by using a liquid target according to the present disclosure can minimize quantitative loss of a reactant by performing the nuclear reaction process using a target of a liquefied state and reusing a liquefied target on which the nuclear reaction process has not been performed, and can improve safety by enabling the radioactive gas generated to be disposed.
    Type: Application
    Filed: June 30, 2020
    Publication date: January 28, 2021
    Inventors: Se Young OH, Sang Moo LIM, Kyo Chul LEE, Joo Hyun KANG
  • Publication number: 20210027906
    Abstract: A method of producing actinium by using liquefied radium can minimize loss of Ra-226 according to the state change of Ac-225 by producing Ac-225 using Ra-226 of a liquefied state, moving the produced Ac-225 in a liquefied state after Ac-225 is produced, and separating and reusing Ac-225, thereby enabling a nuclear reaction process of Ac-225 to be performed. Further, a method of producing actinium by using liquefied radium according to the present disclosure has an effect of enabling safety to be improved by including a radon collection unit which is capable of discharging and isolating radon produced from Ra-226, thereby preventing radiation exposure due to radon.
    Type: Application
    Filed: June 30, 2020
    Publication date: January 28, 2021
    Inventors: Se Young OH, Sang Moo LIM, Kyo Chul LEE, Joo Hyun KANG
  • Patent number: 10870629
    Abstract: The present invention relates to an 18F-labelled compound, and a use thereof. The compound selectively binds to a prostate-specific membrane antigen (PSMA), and enables the acquisition of clear prostate cancer images in a short time when used in positron emission tomography (PET).
    Type: Grant
    Filed: June 18, 2018
    Date of Patent: December 22, 2020
    Assignee: FUTURECHEM CO., LTD.
    Inventors: Dae Yoon Chi, Byoung Se Lee, So Young Chu, Woon Jung Jung, Hyeon Jin Jeong, Min Hwan Kim, Mi Hyun Kim, Kyo Chul Lee, Yong Jin Lee, Ji Ae Park, Ran Ji Yoo, Sang Moo Lim
  • Publication number: 20200207724
    Abstract: The present invention relates to an 18F-labelled compound, and a use thereof. The compound selectively binds to a prostate-specific membrane antigen (PSMA), and enables the acquisition of clear prostate cancer images in a short time when used in positron emission tomography (PET).
    Type: Application
    Filed: June 18, 2018
    Publication date: July 2, 2020
    Inventors: Dae Yoon CHI, Byoung Se LEE, So Young CHU, Woon Jung JUNG, Hyeon Jin JEONG, Min Hwan KIM, Mi Hyun KIM, Kyo Chul LEE, Yong Jin LEE, Ji Ae PARK, Ran Ji YOO, Sang Moo LIM
  • Patent number: 9794521
    Abstract: Provided are apparatuses and methods of resampling event data for quantitative improvement of a PET image, which acquire a quantitatively-improved new PET image by analyzing a storage format of list data prior to conversion into the PET image and nonparametrically resampling event data from the list data based on the analysis results to improve noise and statistical characteristics thereof. The quantitatively improved new PET image may be acquired by analyzing a storage format of list data constituting the PET image and nonparametrically resampling event data to improve noise and statistical characteristics thereof.
    Type: Grant
    Filed: December 22, 2014
    Date of Patent: October 17, 2017
    Assignee: KOREA INSTITUTE OF RADIOLOGICAL & MEDICAL SCIENCES
    Inventors: Sang Keun Woo, Kyeong Min Kim, Tae Won Nam, Ji Min Kim, Sang Moo Lim
  • Patent number: 9395455
    Abstract: Provided is a polyhedral-shaped radiation counter which measures a radiation level of a radioactive material, in which sensor modules configured to measure the radiation level are disposed at vertexes of a polyhedral shape, respectively, and the sensor modules are connected to each other by rod-shaped frame members disposed in edge positions of the polyhedral shape and face parts of the polyhedral shape form an open space.
    Type: Grant
    Filed: June 2, 2015
    Date of Patent: July 19, 2016
    Inventors: Jong Guk Kim, Sang June Jeon, Kyo Chul Lee, Eun Ju Kim, Ji Ae Park, Jung Young Kim, Kyeong Min Kim, Sang Moo Lim
  • Publication number: 20160018539
    Abstract: Provided is an apparatus and method for calculating a correction factor, the apparatus including: a counter configured to acquire first data indicating a counted value of a first radiation source according to an activity and an energy window width, and to acquire second data indicating a coincidence value of a second radiation source according to an activity and an energy window width; and a calculator configured to calculate a correction factor for correcting a difference of the coincidence value of the second radiation source having occurred in response to a single gamma photon emission of the first radiation source, based on the first data and the second data.
    Type: Application
    Filed: September 18, 2014
    Publication date: January 21, 2016
    Applicant: KOREA INSTITUTE OF RADIOLOGICAL & MEDICAL SCIENCES
    Inventors: Jin Su KIM, Young Sub LEE, Hee-Joung KIM, Kyeong Min KIM, Sang-Moo LIM
  • Publication number: 20160003952
    Abstract: Provided is a polyhedral-shaped radiation counter which measures a radiation level of a radioactive material, in which sensor modules configured to measure the radiation level are disposed at vertexes of a polyhedral shape, respectively, and the sensor modules are connected to each other by rod-shaped frame members disposed in edge positions of the polyhedral shape and face parts of the polyhedral shape form an open space.
    Type: Application
    Filed: June 2, 2015
    Publication date: January 7, 2016
    Applicant: KOREA INSTITUTE OF RADIOLOGICAL & MEDICAL SCIENCES
    Inventors: Jong Guk Kim, Sang June Jeon, Kyo Chul Lee, Eun Ju Kim, Ji Ae Park, Jung Young Kim, Kyeong Min Kim, Sang Moo Lim
  • Publication number: 20150185338
    Abstract: An apparatus and method for determining an optimal energy window for optimal positron emission tomography (PET) is disclosed. An optimal energy window determining apparatus may include a data corrector configured to correct data measured from an image quality phantom, an image quality measurer configured to measure an image quality for the corrected data, and an optimal energy window determiner configured to determine the optimal energy window based on the measured image quality. The data corrector may correct the measured data based on a difference between sensitivities measured using different radiopharmaceuticals in at least one energy window.
    Type: Application
    Filed: March 19, 2014
    Publication date: July 2, 2015
    Applicant: KOREA INSTITUTE OF RADIOLOGICAL & MEDICAL SCIENCES
    Inventors: Jin Su KIM, A Ram YU, Hee-Joung KIM, Sang-Moo LIM, Kyeong Min KIM, Gwang Il AN
  • Publication number: 20150186424
    Abstract: Provided are apparatuses and methods of resampling event data for quantitative improvement of a PET image, which acquire a quantitatively-improved new PET image by analyzing a storage format of list data prior to conversion into the PET image and nonparametrically resampling event data from the list data based on the analysis results to improve noise and statistical characteristics thereof. The quantitatively improved new PET image may be acquired by analyzing a storage format of list data constituting the PET image and nonparametrically resampling event data to improve noise and statistical characteristics thereof.
    Type: Application
    Filed: December 22, 2014
    Publication date: July 2, 2015
    Applicant: KOREA INSTITUTE OF RADIOLOGICAL & MEDICAL SCIENCES
    Inventors: Sang Keun Woo, Kyeong Min Kim, Tae Won Nam, Ji Min Kim, Sang Moo Lim
  • Patent number: 9069090
    Abstract: An apparatus and method for determining an optimal energy window for optimal positron emission tomography (PET) is disclosed. An optimal energy window determining apparatus may include a data corrector configured to correct data measured from an image quality phantom, an image quality measurer configured to measure an image quality for the corrected data, and an optimal energy window determiner configured to determine the optimal energy window based on the measured image quality. The data corrector may correct the measured data based on a difference between sensitivities measured using different radiopharmaceuticals in at least one energy window.
    Type: Grant
    Filed: March 19, 2014
    Date of Patent: June 30, 2015
    Assignee: KOREA INSTITUTE OF RADIOLOGICAL & MEDICAL SCIENCES
    Inventors: Jin Su Kim, A Ram Yu, Hee-Joung Kim, Sang-Moo Lim, Kyeong Min Kim, Gwang Il An