Abstract: An embodiment of the present invention provides a fixing assembly comprising: a wire rack having a vertical frame and a horizontal frame; a slide rail which has a fixed rail coupled to the wire rack and a movable rail slidably disposed on the fixed rail; and a fixing means for fastening the fixed rail to the wire rack, wherein the fixing means comprises a first fixing clip provided on one side of the fixed rail and a second fixing clip provided on the other side of the fixed rail. The fixing assembly has a structure in which the first fixing clip is fixed laterally to the horizontal frame, and then the second fixing clip is fixed vertically to the horizontal frame.

Abstract: A composition for preventing or treating synucleinopathies, which includes efavirenz or a salt or solvate thereof and a pharmaceutically acceptable carrier, is provided. The composition is useful in preventing or treating synucleinopathies, such as Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy, because the composition serves to hinder cell-to-cell transmission of alpha-synuclein, prevent intracellular aggregation of ?-synuclein, and inhibit transmission of aggregated ?-synuclein.

Abstract: A composition for preventing or treating synucleinopathies, which includes nevirapine or a salt or solvate thereof and a pharmaceutically acceptable carrier, is provided. The composition is useful in preventing or treating synucleinopathies, such as Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy, because the composition serves to hinder cell-to-cell transmission of ?-synuclein, prevent intracellular aggregation of ?-synuclein, and inhibit transmission of aggregated ?-synuclein.

Abstract: A composition including a substance that inhibits an expression or activity of c-src and its use in inhibiting aggregation and/or migration of ?-syn are disclosed. The composition may be a pharmaceutical composition and can be used for preventing or treating synucleinopathy. The substance can inhibit the signal transduction induced by ?-syn migrating to adjacent cells, thus mitigating the cytotoxic influence of ?-syn on the adjacent cells; and can inhibit the denaturation of monomeric ?-syn into aggregated ?-syn, which may be a major cause of synucleinopathy, and thus, can be beneficially used as a therapeutic agent for synucleinopathy.

Abstract: A refrigeration system includes a compressor configured to compress a refrigerant, a condenser configured to condense the compressed refrigerant introduced from the compressor, a main flow passage configured to deliver the refrigerant compressed in the compressor to the condenser, a heat storage tank configured to partially store the heat of the refrigerant discharged from the compressor, an auxiliary flow passage configured to deliver the refrigerant compressed in the compressor to the heat storage tank, an expansion valve configured to expand the refrigerant condensed in the condenser, and an evaporation-side composite heat exchanger configured to evaporate the expanded refrigerant.

Abstract: The present invention relates to a system for cooling a quick-freezing chamber at ?40 to ?30° C., a freezing chamber at ?20 to ?15° C., a refrigerating chamber at 0 to 5° C., and the like and an energy-saving defrosting system for defrosting the quick-freezing chamber, the freezing chamber, and the refrigerating chamber using condensed waste heat.

Abstract: The present invention provides a compound having an effect of preventing and/or treating the damage or degeneration of cochlear (and vestibular) mother cells and spiral ganglion neurons by downregulating a cysteinyl leukotriene receptor. Particularly, the present invention provides a composition for preventing or treating sensorineural hearing loss, containing a cysteinyl leukotriene receptor and a Ginkgo biloba extract as active ingredients, on the basis of the co-administration of a cysteinyl leukotriene receptor and a Ginkgo biloba extract having an excellent effect of protecting hearing.

Abstract: Disclosed is a heat pump heating/cooling system that uses a hybrid heat source that may include air heat, groundwater heat, brine and in-line heaters. The heat pump includes 1) a device for compressing, condensing, gasifying, and circulating cooling/heating media and exchanging heat with water refrigerant; 2) a device for storing heat energy in a storage tank; 3) a device for loading a load through a four-way fan coil unit; and 4) a control panel. To remove frost on the exterior of an evaporator, the evaporator is temporarily stopped, and brine at a temperature of 15° C. to 20° C., which receives groundwater heat from a brine heat exchanger and receives heat from an in-line heater, is supplied to a brine supply pipe installed around the evaporator to melt and remove the frost on the exterior of the evaporator and then is discharged at a temperature of ?3° C. to 5° C.

Abstract: A refrigeration system using waste heat recovery by refrigerator discharge gas is disclosed.

Abstract: This invention provides a method of treating a neurodegenerative disease selected from the group consisting of Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy, comprising administering a pharmaceutically effective amount of an agent capable of suppressing expression or activity of SHP-1/-2 (Src homology region 2 domain-containing phosphatase-1/-2) or Fc?RIIB (IgG Fc receptor II-B) to a subject having the neurodegenerative disease, wherein the agent capable of suppressing expression of SHP-1/-2 or Fc?RIIB is selected from the group consisting of miRNA, siRNA, shRNA, antisense oligonucleotide, and a combination thereof capable of specifically binding to mRNA of SHP-1/-2 or Fc?RIIB, and the agent capable of suppressing activity of SHP-1/-2 or Fc?RIIB is selected from the group consisting of an antibody, an aptamer, an antagonist, and a combination thereof capable of specifically binding to a protein of SHP-1/-2 or Fc?RIIB.

Abstract: The present invention provides a compound having an effect of preventing and/or treating the damage or degeneration of cochlear (and vestibular) mother cells and spiral ganglion neurons by downregulating a cysteinyl leukotriene receptor. Particularly, the present invention provides a composition for preventing or treating sensorineural hearing loss, containing a cysteinyl leukotriene receptor and a ginkgo biloba extract as active ingredients, on the basis of the co-administration of a cysteinyl leukotriene receptor and a ginkgo biloba extract having an excellent effect of protecting hearing.

Abstract: Provided are a pharmaceutical composition for preventing or treating neurodegenerative diseases including an agent capable of suppressing expression or activity of SHP-1/-2 or Fc?RIIB, a method of preventing or treating neurodegenerative diseases by administering the pharmaceutical composition, a method of screening for a therapeutic agent for neurodegenerative diseases, a diagnostic composition for neurodegenerative diseases, a diagnostic kit for neurodegenerative diseases including the diagnostic composition, and a method of providing information for the diagnosis of neurodegenerative diseases by using the diagnostic composition or kit. The agent capable of suppressing expression or activity of SHP-1/-2 or Fc?RIIB according to the present invention inhibits signal transduction caused by propagation of ?-synuclein to neighboring cells, thereby reducing cytotoxicity of ?-synuclein to neighboring cells and thus being usefully applied to a therapeutic agent for neurodegenerative diseases.

Abstract: An apparatus for defrosting an evaporator in a refrigeration system using an infrared emitting diode includes i) a frost detection sensor configured to receive a frost sensing signal from an output part of a control processor and to transmit a frost detection signal into an input part of a control processor, wherein the frost detection signal is generated by projecting infrared to the frost and receiving reflection-infrared from the frost; ii) a control processor configured to convert the frost detection signal into a digital signal in the signal converting part, to evaluate if the frost detection signal is higher than a threshold value which is set from a signal setting part, and to transmit the operation signal to the defroster, as well as the display signal to the signal display part; and iii) a defroster.

Abstract: Disclosed is a heat pump heating/cooling system that uses a hybrid heat source that may include air heat, groundwater heat, brine and in-line heaters. The heat pump includes 1) a device for compressing, condensing, gasifying, and circulating cooling/heating media and exchanging heat with water refrigerant; 2) a device for storing heat energy in a storage tank; 3) a device for loading a load through a four-way fan coil unit; and 4) a control panel. To remove frost on the exterior of an evaporator, the evaporator is temporarily stopped, and brine at a temperature of 15° C. to 20° C., which receives groundwater heat from a brine heat exchanger and receives heat from an in-line heater, is supplied to a brine supply pipe installed around the evaporator to melt and remove the frost on the exterior of the evaporator and then is discharged at a temperature of ?3° C. to 5° C.

Abstract: The present invention relates to an apparatus for defrosting an evaporator in refrigeration system using infrared emitting diode sensor comprising: i) a frost detection sensor (50) configured to receive the frost sensing signal from the output part of a control processor (60), and to transmit the frost detection signal into the input part of a control processor (60), wherein the frost detection signal is generated by projecting infrared to the frost and projecting and receiving reflection-infrared from the frost; ii) a control processor (60) configured to convert the frost detection signal into digital signal in the signal converting part, to evaluate if the frost detection signal is higher than threshold value which is set from signal setting part (61), and to transmit the operation signal to the defroster (70) as well as the display signal to the signal display part (62); and iii) a defroster (70) configured to be operated depending on the signal from the control processor (60).