Patents by Inventor Sang-Ryoul Park

Sang-Ryoul Park has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10253378
    Abstract: The present invention relates to utilization of an artificially synthesized nucleic acid, and more particularly, to a quantitative analysis method capable of quantitatively adjusting gene-based microbial community analysis results by preparing a microorganism 16S rDNA gene, which has a single nucleotide polymorphism (SNP) at a particular location so as to be differentiated from a gene of a target microorganism on the nucleotide sequence, and then using the microorganism 16S rDNA gene as an internal standard material which is quantifiable through nucleotide sequencing.
    Type: Grant
    Filed: November 18, 2014
    Date of Patent: April 9, 2019
    Assignee: Korea Research Institute of Standards and Science
    Inventors: Inchul Yang, Hannah Yu, Hyo-jin Yang, Sook-Kyung Kim, Sang-Ryoul Park
  • Publication number: 20180011004
    Abstract: The present invention relates to a measurement device including a trace sample-use high sensitivity light absorbing cell, the device comprising: a light absorbing cell containing a capillary tube of which both ends are open hollow shaped; a light absorbing cell mounting block on which one end of the light absorbing cell is mounted, and which comprises a light emitting unit, disposed on the upper portion of the light absorbing cell, for irradiating light to one end of the light absorbing cell; and a light receiving block which comprises a light metering immersion unit disposed in such a manner that the other end of the light absorbing cell is immersed in a sample contained therein, and which detects light that is irradiated to one end of the light absorbing cell and emitted to the other end thereof.
    Type: Application
    Filed: September 5, 2017
    Publication date: January 11, 2018
    Inventors: Sang-Ryoul PARK, Hee-Bong YOO, Juhwang KIM
  • Patent number: 9598717
    Abstract: Provided are an enzyme treatment apparatus for proteins using a hollow fiber membrane and an on-line proteomics method using same. The enzyme treatment apparatus for proteins according to the present invention can increase a recovery rate of peptides, which are recovered through an enzyme treatment process, by basically solving the problem of low reproducibility of an enzyme activity which may occur during a conventional enzyme treatment process, and can also reduce a time for purification and provide higher yield by performing separation and purification through a single step. In particular, the present invention can be usefully applied for developing a disease-specific protein biomarker through a statistical analysis method having highly efficient detectability for proteins in research for finding biomarkers related to human diseases.
    Type: Grant
    Filed: September 18, 2012
    Date of Patent: March 21, 2017
    Assignee: KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE
    Inventors: Duk Jin Kang, Sang Ryoul Park, Sook-Kyung Kim
  • Publication number: 20160376638
    Abstract: The present invention relates to utilization of an artificially synthesized nucleic acid, and more particularly, to a quantitative analysis method capable of quantitatively adjusting gene-based microbial community analysis results by preparing a microorganism 16S rDNA gene, which has a single nucleotide polymorphism (SNP) at a particular location so as to be differentiated from a gene of a target microorganism on the nucleotide sequence, and then using the microorganism 16S rDNA gene as an internal standard material which is quantifiable through nucleotide sequencing.
    Type: Application
    Filed: November 18, 2014
    Publication date: December 29, 2016
    Applicant: KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE
    Inventors: Inchul Yang, Hannah Yu, Hyo-jin Yang, Sook-Kyung Kim, Sang-Ryoul Park
  • Patent number: 9297038
    Abstract: Disclosed are a method and a kit for the quantification of nucleic acids, especially a trace amount of nucleic acid, such as host cell nucleic acid impurities, using real-time PCR with a random primer.
    Type: Grant
    Filed: November 9, 2011
    Date of Patent: March 29, 2016
    Assignee: KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE
    Inventors: In Chul Yang, Min Jung Kang, Han Nah Yu, Sang Ryoul Park, Sook Kyoung Kim
  • Publication number: 20140302545
    Abstract: Provided are an enzyme treatment apparatus for proteins using a hollow fiber membrane and an on-line proteomics method using same. The enzyme treatment apparatus for proteins according to the present invention can increase a recovery rate of peptides, which are recovered through an enzyme treatment process, by basically solving the problem of low reproducibility of an enzyme activity which may occur during a conventional enzyme treatment process, and can also reduce a time for purification and provide higher yield by performing separation and purification through a single step. In particular, the present invention can be usefully applied for developing a disease-specific protein biomarker through a statistical analysis method having highly efficient detectability for proteins in research for finding biomarkers related to human diseases.
    Type: Application
    Filed: September 18, 2012
    Publication date: October 9, 2014
    Applicant: KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE
    Inventors: Duk Jin Kang, Sang Ryoul Park, Sook-Kyung Kim
  • Publication number: 20130295577
    Abstract: Disclosed are a method and a kit for the quantification of nucleic acids, especially a trace amount of nucleic acid, such as host cell nucleic acid impurities, using real-time PCR with a random primer.
    Type: Application
    Filed: November 9, 2011
    Publication date: November 7, 2013
    Applicant: KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE
    Inventors: In Chul Yang, Min Jung Kang, Han Nah Yu, Sang Ryoul Park, Sook Kyoung Kim
  • Patent number: 7993507
    Abstract: The present invention is related to a method of separation of compounds by electrophoresis in which the compounds such as genes, proteins, etc. may be analyzed very precisely as samples are introduced directly into the separation tubes of the chip at the collection site, and therefore, it is not necessary to have separate fluid paths or individual sample storing apparatus that have been necessary for the conventional electrophoresis; it is easy to make the chips as the structure of the chip becomes extremely simple, and high-density arrangement of the separation tubes is enabled; and further, the compounds such as genes, proteins, etc. may be analyzed very precisely without interference in the storage tubs by using a non-polar solvent as the solvent of the sample storage tub.
    Type: Grant
    Filed: November 16, 2005
    Date of Patent: August 9, 2011
    Assignee: Korea Research Institute of Standards and Science
    Inventors: Sang-Ryoul Park, In-Chul Yang, Young-Ho Kim
  • Patent number: 7731827
    Abstract: The invention relates to a method for capturing charged molecules of interest traveling in an electrolyte flow stream through an electrically non-conductive channel, comprising at least one anode and at least one cathode individually separated from said channel, but in electrical contact with said flow stream, by a conductive ion selective semi-permeable membrane. Said membrane interferes with the normal migration of ions towards its respective electrode, generating at least two zones of different electric field. Balance between hydrodynamic and electrical forces captures certain ions into the flow stream. it also relates to a device for performing the method.
    Type: Grant
    Filed: June 17, 2005
    Date of Patent: June 8, 2010
    Assignees: PerkinElmer Health Sciences, Inc., Biomotif AB, Hans Jornvall
    Inventors: Juan Astorga-Wells, Sang-Ryoul Park, Harold Swerdlow, Gerald Jesson, Ulf Lindberg, Tomas Bergman, Hans Jornvall, Mats Jonsson
  • Publication number: 20080047834
    Abstract: The present invention is related to a method of separation of compounds by electrophoresis in which the compounds such as genes, proteins, etc. may be analyzed very precisely as samples are introduced directly into the separation tubes of the chip at the collection site, and therefore, it is not necessary to have separate fluid paths or individual sample storing apparatus that have been necessary for the conventional electrophoresis; it is easy to make the chips as the structure of the chip becomes extremely simple, and high-density arrangement of the separation tubes is enabled; and further, the compounds such as genes, proteins, etc. may be analyzed very precisely without interference in the storage tubs by using a non-polar solvent as the solvent of the sample storage tub.
    Type: Application
    Filed: November 16, 2005
    Publication date: February 28, 2008
    Applicant: Korea Research Institute of Standards and Science
    Inventors: Sang-Ryoul Park, In-Chul Yang, Young-Ho Kim
  • Patent number: 7294467
    Abstract: The present invention is related to a novel approach for quantitation of DNA based on the stoichiometric existence of phosphorus (P) in DNA.
    Type: Grant
    Filed: May 26, 2005
    Date of Patent: November 13, 2007
    Assignee: Korea Research Institute of Standard and Science
    Inventors: Sang-Ryoul Park, In-Chul Yang, Myung-Sub Han, Yong-Hyeon Yim, Eui-Jin Hwang
  • Publication number: 20060078905
    Abstract: The present invention is related to a novel approach for quantitation of DNA based on the stoichiometric existence of phosphorus (P) in DNA.
    Type: Application
    Filed: May 26, 2005
    Publication date: April 13, 2006
    Inventors: Sang-Ryoul Park, In-Chul Yang, Myung-Sub Han, Yong-Hyeon Yim, Eui-Jin Hwang
  • Publication number: 20050284762
    Abstract: The invention relates to a method for capturing charged molecules of interest traveling in an electrolyte flow stream through an electrically non-conductive channel, comprising at least one anode and at least one cathode individually separated from said channel, but in electrical contact with said flow stream, by a conductive ion selective semi-permeable membrane. Said membrane interferes with the normal migration of ions towards its respective electrode, generating at least two zones of different electric field. Balance between hydrodynamic and electrical forces captures certain ions into the flow stream. it also relates to a device for performing the method.
    Type: Application
    Filed: June 17, 2005
    Publication date: December 29, 2005
    Applicant: Capture Device AB
    Inventors: Juan Astorga-Wells, Sang-Ryoul Park, Harold Swerdlow, Gerald Jesson, Ulf Lindberg, Tomas Bergman, Hans Jornvall, Mats Jonsson