Patents by Inventor SANG YEUL HAN

SANG YEUL HAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-ANG2 antibody
    Patent number: 11174309
    Abstract: An anti-Ang2 antibody or an antigen-binding fragment thereof that specifically binds to an angiogenesis-inducing factor Angiopoietin-2 (Ang2) and complexes with a Tie2 receptor and Ang2, and related methods and compositions.
    Type: Grant
    Filed: November 27, 2017
    Date of Patent: November 16, 2021
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Kyung Eun Kim, Seung Ja Oh, Hyo Seon Lee, Sang Yeul Han
  • Humanized or affinity-matured anti ang-2 antibody and uses thereof
    Patent number: 10934350
    Abstract: An anti-Ang2 antibody or an antigen-binding fragment thereof that specifically binds to an angiogenesis-inducing factor Angiopoietin-2 (Ang2) and complexes with a Tie2 receptor through Ang2, and methods of using the same.
    Type: Grant
    Filed: June 11, 2018
    Date of Patent: March 2, 2021
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Seok Kyun Kim, Sunghyun Kim, Sang Yeul Han, Seung Hyun Lee, Su Jin Kim, Yong In Kim, Hyung-Chan Kim, Kwang Hoon Lee, Hyo Seon Lee
  • Fusion polypeptide capable of binding simultaneously to VEGF-C and VEGF-D
    Patent number: 10246511
    Abstract: A fusion polypeptide capable of binding simultaneously to angiopoietin 2, VEGF-C and VEGF-D; or capable of binding simultaneously to VEGF-C and VEGF-D, and methods for the preparation and use thereof.
    Type: Grant
    Filed: August 2, 2017
    Date of Patent: April 2, 2019
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Kwang Hoon Lee, Hyung-Chan Kim, Sang Yeul Han, Seok Kyun Kim, Kyung Eun Kim
  • HUMANIZED OR AFFINITY-MATURED ANTI ANG-2 ANTIBODY AND USES THEREOF
    Publication number: 20180273613
    Abstract: An anti-Ang2 antibody or an antigen-binding fragment thereof that specifically binds to an angiogenesis-inducing factor Angiopoietin-2 (Ang2) and complexes with a Tie2 receptor through Ang2, and methods of using the same.
    Type: Application
    Filed: June 11, 2018
    Publication date: September 27, 2018
    Inventors: Seok Kyun Kim, Sunghyun Kim, Sang Yeul Han, Seung Hyun Lee, Su Jin Kim, Yong In Kim, Hyung-Chan Kim, Kwang Hoon Lee, Hyo Seon Lee
  • Angiopoietin-2 specific antibodies and uses thereof
    Patent number: 10047154
    Abstract: An Ang2 specific antibody, a method of inhibiting angiogenesis or a method of treating a disease related to the activation and/or overproduction of Ang2 using the antibody, and a composition for diagnosing a disease related to the activation and/or overproduction of Ang2 including the antibody.
    Type: Grant
    Filed: July 30, 2014
    Date of Patent: August 14, 2018
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Seok Kyun Kim, Sang Yeul Han, Kwang Hoon Lee, Kyung Eun Kim, Chung Ho Kim, Yong In Kim, Hyung-Chan Kim, Yoon Sook Lee, Hyo Seon Lee
  • Humanized or affinity-matured anti Ang-2 antibody and uses thereof
    Patent number: 9994632
    Abstract: An anti-Ang2 antibody or an antigen-binding fragment thereof that specifically binds to an angiogenesis-inducing factor Angiopoietin-2 (Ang2) and complexes with a Tie2 receptor through Ang2, and methods of using the same.
    Type: Grant
    Filed: May 26, 2015
    Date of Patent: June 12, 2018
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Seok Kyun Kim, Sunghyun Kim, Sang Yeul Han, Seung Hyun Lee, Su Jin Kim, Yong In Kim, Hyung-Chan Kim, Kwang Hoon Lee, Hyo Seon Lee
  • ANTI-ANG2 ANTIBODY
    Publication number: 20180086825
    Abstract: An anti-Ang2 antibody or an antigen-binding fragment thereof that specifically binds to an angiogenesis-inducing factor Angiopoietin-2 (Ang2) and complexes with a Tie2 receptor and Ang2, and related methods and compositions.
    Type: Application
    Filed: November 27, 2017
    Publication date: March 29, 2018
    Inventors: Kyung Eun Kim, Seung Ja Oh, Hyo Seon Lee, Sang Yeul Han
  • Method of blocking vascular leakage using an anti-ANG2 antibody
    Patent number: 9902767
    Abstract: A method for the prevention and/or treatment of a disease accompanied by vascular leakage and/or vascular inflammation comprising administering an anti-Ang2 antibody or an antigen-binding fragment thereof that specifically binds to an angiogenesis-inducing factor Angiopoietin-2 (Ang2) and forms a complex with a Tie2 receptor and Ang2.
    Type: Grant
    Filed: July 29, 2014
    Date of Patent: February 27, 2018
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Hyo Seon Lee, Kyung Eun Kim, Seung Ja Oh, Sang Yeul Han
  • FUSION POLYPEPTIDE INHIBITING VEGF-C, VEGF-D AND/OR ANGIOPOIETIN-2, AND USE THEREOF
    Publication number: 20170342153
    Abstract: A fusion polypeptide capable of binding simultaneously to angiopoietin 2, VEGF-C and VEGF-D; or capable of binding simultaneously to VEGF-C and VEGF-D, and methods for the preparation and use thereof.
    Type: Application
    Filed: August 2, 2017
    Publication date: November 30, 2017
    Inventors: Kwang Hoon Lee, Hyung-Chan Kim, Sang Yeul Han, Seok Kyun Kim, Kyung Eun Kim
  • Anti-Ang2 antibody
    Patent number: 9828422
    Abstract: An anti-Ang2 antibody or an antigen-binding fragment thereof that specifically binds to an angiogenesis-inducing factor Angiopoietin-2 (Ang2) and complexes with a Tie2 receptor and Ang2, and related methods and compositions.
    Type: Grant
    Filed: July 29, 2014
    Date of Patent: November 28, 2017
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Kyung Eun Kim, Seung Ja Oh, Hyo Seon Lee, Sang Yeul Han
  • Fusion polypeptide inhibiting VEGF-C, VEGF-D and/or angiopoietin-2, and use thereof
    Patent number: 9725513
    Abstract: A fusion polypeptide capable of binding simultaneously to angiopoietin 2, VEGF-C and VEGF-D; or capable of binding simultaneously to VEGF-C and VEGF-D, and methods for the preparation and use thereof.
    Type: Grant
    Filed: July 21, 2014
    Date of Patent: August 8, 2017
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Kwang Hoon Lee, Hyung-Chan Kim, Sang Yeul Han, Seok Kyun Kim, Kyung Eun Kim
  • IMMUNOPOTENTIATOR CONTAINING ANTI-ANG2 ANTIBODY
    Publication number: 20170183399
    Abstract: Provided is a method of potentiating immunity or preventing or treating an immune-related disease comprising administering an anti-Ang2 antibody or an antigen-binding fragment thereof to a subject in need thereof.
    Type: Application
    Filed: December 21, 2016
    Publication date: June 29, 2017
    Inventors: Yuhoi Kang, Hojun Lee, Hongseok Jo, Sang Chul Park, Sang Yeul Han
  • HYPOGLYCEMIC AGENT CONTAINING ANTI-ANG2 ANTIBODY
    Publication number: 20170183401
    Abstract: Provided is a method of decreasing blood sugar level or preventing and/or treating a hyperglycemia-related disease, including administering an anti-Ang2 antibody or an antigen-biding fragment thereof to a subject in need thereof.
    Type: Application
    Filed: December 21, 2016
    Publication date: June 29, 2017
    Inventors: Hongseok Jo, Sang Yeul Han, Joo-Hye Song, Yuhoi Kang, Young Jun Koh, Sang Chul Park, Hojun Lee
  • Antibody specifically binding to ANG2 and use thereof
    Patent number: 9580497
    Abstract: An Ang2 specific antibody, a method of preventing and/or treating a disease related to the activation and/or overproduction (overexpression) of Ang2 by administering the antibody to a subject, and a method of screening a candidate substance for diagnosing, preventing, or treating a disease related to activation or overproduction of Ang2.
    Type: Grant
    Filed: January 27, 2015
    Date of Patent: February 28, 2017
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Kyung Eun Kim, Yoon Sook Lee, Sang Yeul Han, Hyung-Chan Kim, Kwang Hoon Lee, Hyo Seon Lee, Seok Kyun Kim
  • Antibodies or antigen-binding fragments thereof specifically binding to VEGF-C and use thereof
    Patent number: 9562093
    Abstract: An antibody or antigen-binding fragment thereof that specifically binds to and inhibits VEGF-C and uses thereof in a method of inhibiting angiogenesis and a method of preventing, treating, and/or diagnosing a disease associated with activation and/or overexpression of VEGF-C, using the antibody, and a method of detecting the presence of VEGF-C in a sample.
    Type: Grant
    Filed: October 20, 2014
    Date of Patent: February 7, 2017
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Seok Kyun Kim, Sang Yeul Han, Kwang Hoon Lee, Kyung Eun Kim
  • Ang-2 specific antibodies and uses thereof
    Patent number: 9527910
    Abstract: Provided are an anti-Ang-2 antibody or antigen-binding fragment thereof that specifically binds to an angiogenesis-inducing factor Angiopoietin-2 (Ang-2), related compositions and pharmaceutical compositions, and methods for using such compositions and pharmaceutical compositions.
    Type: Grant
    Filed: July 2, 2014
    Date of Patent: December 27, 2016
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Yoon Sook Lee, Chung Ho Kim, Kyung Eun Kim, Hyung-Chan Kim, Kwang Hoon Lee, Hyo Seon Lee, Sang Yeul Han
  • Use of an anti-Ang2 antibody
    Patent number: 9505841
    Abstract: A method of preventing or treating cancer using an anti-Ang2 antibody or an antigen-binding fragment thereof that specifically binds to an angiogenesis-inducing factor Angiopoietin-2 (Ang2) and complexes to a Tie2 receptor while bound with Ang2.
    Type: Grant
    Filed: July 29, 2014
    Date of Patent: November 29, 2016
    Assignees: SAMSUNG ELECTRONICS CO., LTD., KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Kyung Eun Kim, Sang Yeul Han, Gou Young Koh, Hyo Seon Lee, Chan Kim
  • PEPTIDE FOR INHIBITION OF BINDING BETWEEN ANGIOPOIETIN-2 AND INTEGRIN AND USE THEREOF
    Publication number: 20160101154
    Abstract: Angiopoietin-2 (Ang2) derived peptides, polypeptides, and peptide complexes, and a method for inhibition of binding between Ang2 and integrin and prevention and/or treatment of a disease caused by the activation of Ang2 or the binding between Ang2 and integrin using the peptide, polypeptides, and peptide complexes.
    Type: Application
    Filed: October 21, 2015
    Publication date: April 14, 2016
    Inventors: Sang Yeul Han, Chung Ho Kim, Kyung Eun Kim, Hyung-Chan Kim, Kwang-Hoon Lee, Hyo Seon Lee
  • HUMANIZED OR AFFINITY-MATURED ANTI ANG-2 ANTIBODY AND USES THEREOF
    Publication number: 20150337033
    Abstract: An anti-Ang2 antibody or an antigen-binding fragment thereof that specifically binds to an angiogenesis-inducing factor Angiopoietin-2 (Ang2) and complexes with a Tie2 receptor through Ang2, and methods of using the same.
    Type: Application
    Filed: May 26, 2015
    Publication date: November 26, 2015
    Inventors: Seok Kyun Kim, Sunghyun Kim, Sang Yeul Han, Seung Hyun Lee, Su Jin Kim, Yong In Kim, Hyung-Chan Kim, Kwang Hoon Lee, Hyo Seon Lee
  • Peptide for inhibition of binding between angiopoietin-2 and integrin and use thereof
    Patent number: 9193768
    Abstract: There are provided an angiopoietin-2 (Ang2) derived peptides, polypeptides, and peptide complexes, and a method for inhibition of binding between Ang2 and integrin and prevention and/or treatment of a disease caused by the activation of Ang2 or the binding between Ang2 and integrin using the peptide, polypeptides, and peptide complexes.
    Type: Grant
    Filed: October 18, 2013
    Date of Patent: November 24, 2015
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Sang Yeul Han, Chung Ho Kim, Kyung Eun Kim, Hyung-Chan Kim, Kwang-Hoon Lee, Hyo Seon Lee