Abstract: The present invention relates to a food having improved flavor, nutrition and color and a method for producing the same, and more specifically, to a food having a flavor, nutrition and color similar to those of meat, the food containing either a compound selected from the group consisting of heme, porphyrins, metalloporphyrins, and porphyrin analogs, or a microorganism that produces the compound, and a method for producing the same. According to the present invention, it is possible to improve the flavor, nutrition, and color of food by producing heme and various porphyrins, metalloporphyrins, and porphyrin analogs with high efficiency by fermentation of a microbial mutant, isolating/purifying the products, and adding the isolated/purified products to food.

Abstract: The present invention relates to a recombinant microorganism imparted with increased ability to produce glutaric acid by further introducing a gene encoding a polypeptide having glutaric acid transporter activity into a microorganism having ability to produce glutaric acid, and to a method of preparing glutaric acid using the recombinant microorganism. According to the present invention, glutaric acid used for the preparation of various compounds such as polyamide, polyurethane, 1,5-pentanediol, and 5-hydroxyvaleric acid can be biosynthesized at high yield.

Abstract: The present invention relates to novel C-glycosyltransferase variants and a use thereof. The C-glycosyltransferase variants according to the present invention have improved glycosidic bond-forming ability as compared with wild-type C-glycosyltransferase, and thus can increase the glycoside production effects of polyketide groups and pseudo-natural products, particularly type I, II, III polyketide, nonribosomal peptides, phenylpropanoids, and other aromatic natural products, and thus can be useful for the preparation of a drug, a food additive, a nutritional supplement, and the like containing a C-glycoside compound as a constituent ingredient.

Abstract: A deepfake detection device may include a data input unit that receives an input image including a low-quality deepfake video, a branch-based super-resolution training unit that enhances the resolution of the input image through unsupervised super-resolution training and generates a plurality of super-resolution images having different sizes, and a multi-scale training unit that performs multi-scale training, without resolution conversion, on the plurality of super-resolution images having different sizes, respectively. The multi-scale training unit may synthesize multi-scale training results for the plurality of super-resolution images having different sizes, respectively, and determine whether the input image is a deepfake based on the multi-scale training results.

Abstract: The present invention provides a composition for antifreezing including a gold (Au) nanostructure in which at least a portion thereof is concave, thereby it is possible to increase a survival rate of cells due to having excellent effect of inhibiting ice recrystallization when cryopreservation of the cells, and maintain a texture of food even when using in the freezing of food.

Abstract: The present disclosure relates to a mutant microorganism in which a glycerol catabolic pathway and a 1,3-PDO biosynthetic pathway are introduced into a microorganism incapable of using glycerol as a carbon source, and a method of producing 1,3-PDO using the same. According to the present disclosure, it is possible to produce 1,3-PDO while growing a mutant microorganism having 1,3-PDO production ability by using the inexpensive raw material glycerol as a single carbon source. Thus, the present disclosure is useful for the economical production of 1,3-PDO.

Abstract: A nanocatalyst for partial oxidation of methane is disclosed. The nanocatalyst is prepared by carbonizing a metal-organic framework coordinated with copper ions to form a structure in which nitrogen atoms present in a nitrogen-doped porous carbon structure form coordinate bonds with copper ions. This structure enhances the chemical stability of the nanocatalyst, prevents the peroxidation of methane at low temperature, and significantly improves the conversion efficiency of methane to liquid products such as methanol and methyl hydroperoxide by selective partial oxidation of methane gas. Also disclosed are a method for preparing the nanocatalyst and a method for partial oxidation of methane using the nanocatalyst.

Abstract: Synthetic sRNA for inhibiting prokaryote gene expression is described, which includes (i) an Hfq binding site and (ii) a region that forms a complementary bond with a target gene mRNA. Vectors encoding the synthetic sRNA are described, as well as recombinant prokaryotes transformed with such vectors, methods of inhibiting prokaryote gene expression, and methods of gene screening and strain improvement. The synthetic sRNA is able to control single and multiple target genes at a time, and is particularly useful for inhibiting a gene expression of Gram-positive bacteria, e.g., in a recombinant Corynebacterium for mass production of high value products that do not require fossil fuels with associated environmental problems.

Abstract: The present invention relates to a recombinant microorganism having enhanced ability to produce recombinant silk protein and a method of producing high-molecular-weight recombinant silk protein using the same, and more specifically, to a recombinant microorganism having an enhanced ability to produce spider silk protein, obtained by introducing a sequence encoding a synthetic sRNA that inhibits expression of eno gene into a microorganism having ability to produce recombinant silk protein. The recombinant silk protein derived from the recombinant strain according to the invention has a high molecular weight similar to that of dragline silk protein produced by spiders, and may be mass-produced, and thus it has properties similar to or better than those of natural silk protein when manufactured into fibers. Accordingly, the recombinant silk protein may be advantageously used in various industrial fields such as bioengineering and/or pharmaceutical fields where spider silk fibers are expected to be applied.

Abstract: The present invention provides a a nanostructure which includes: a core comprising one or more planes configured to come into planar contact with at least one plane of an ice crystal; and an oligopeptide which is conjugated to at least one plane of the core and comprises (Thr)n-, (Ala)n-, (Ser)n-, or (Gly)n-, wherein the nanostructure is a polyhedron-shaped nanostructure present in water in a colloidal form to control freezing, and n is an integer of 2 to 7.

Abstract: The present specification relates to an apparatus and a method for detecting a deepfake based on a convolutional long short-term memory network. The method of detecting a deepfake includes receiving, by an input unit, a plurality of training datasets selected from a plurality of domains; training, by a learning unit, a deepfake detection model based on the training datasets; and detecting, by a detection unit, whether a deepfake is present from the test datasets using the trained deepfake detection model. The training of the deepfake detection model includes sequentially training the deepfake detection model through initial learning using training datasets of a specific domain among the plurality of domains and transfer learning using training datasets of domains other than the specific domain.

Abstract: Disclosed are a mutant microorganism for producing succinic acid exhibiting improved activity of conversion of oxaloacetate to malate through the introduction of genes encoding a malate dehydrogenase, wherein an amino acid residue that interacts with a pyrophosphate moiety of NADH through an amide functional group of a main chain of malate dehydrogenase is glutamine (Gln), and a method of producing succinic acid using the same. The mutant microorganism producing succinic acid according to the present invention is capable of producing a high concentration of succinic acid at the highest productivity compared to other mutant microorganisms reported to date when the microorganism is cultured in a limited medium. In addition, the mutant microorganism is capable of producing succinic acid at higher productivity and product concentration through further advanced fermentation technology.

Abstract: A nanocatalyst for partial oxidation of methane is disclosed. The nanocatalyst is prepared by carbonizing a metal-organic framework coordinated with copper ions to form a structure in which nitrogen atoms present in a nitrogen-doped porous carbon structure form coordinate bonds with copper ions. This structure enhances the chemical stability of the nanocatalyst, prevents the peroxidation of methane at low temperature, and significantly improves the conversion efficiency of methane to liquid products such as methanol and methyl hydroperoxide by selective partial oxidation of methane gas. Also disclosed are a method for preparing the nanocatalyst and a method for partial oxidation of methane using the nanocatalyst.

Abstract: The present invention relates to a method for predicting a drug-drug interaction and a drug-food interaction by using structural information of a drug and, more particularly, to a method for predicting the mechanism of action and activity of a drug interaction through interaction prediction results expressed by a standardized sentence. When using a method for predicting a drug interaction according to the present invention, a drug interaction can be predicted quickly and accurately, and in particular, activity information of an unknown compound can also be predicted by expressing a prediction result by means of a sentence, and thus the method is very useful for developing a drug exhibiting desired activity without causing adverse effects.

Abstract: Disclosed is a recombinant microorganism capable of growing using only carbon dioxide and formic acid by introducing and improving a metabolic pathway for synthesizing pyruvic acid from carbon dioxide and formic acid to enhance pyruvic acid synthesis efficiency and performing additional genetic manipulation, and a method for producing useful substances using the same. Advantageously, the recombinant microorganism is capable of synthesizing pyruvic acid, a C3 organic compound, at a remarkably improved rate, and in particular, grows well even in a medium containing only carbon dioxide and formic acid as carbon sources without a glucose supply, and is thereby capable of synthesizing pyruvic acid and various high value-added compounds using the same as an intermediate product in an economically efficient manner.

Abstract: A marketing system that supports sales of goods by interlocking a customer terminal and an administrator terminal including a central server which provides an event page production tool to the administrator terminal, receives information about an event page, and transmits to the customer terminal; an administrator terminal for receiving the event page production tool from the central server to input corresponding variables to produce an event page; and a customer terminal for receiving the event page produced by the administrator terminal from the central server and inputting necessary information.

Abstract: The present invention relates to recombinant Corynebacterium having 1,3-PDO productivity and reduced 3-HP productivity, and a method for producing 1,3-PDO by using same. When a Corynebacterium glutamicum variant according to the present invention is used, the productivity of 3-HP, which is a by-product, is inhibited by using low-cost glycerol as a carbon source, and thus 1,3-PDO can be produced with high efficiency.

Abstract: The present invention relates to a pharmaceutical composition for preventing or treating coronavirus disease 2019, and more specifically to a pharmaceutical composition for preventing or treating coronavirus disease 2019 found by drug repositioning technology using drug virtual screening technology. The pharmaceutical composition for preventing or treating coronavirus disease 2019 according to the present invention is a composition obtained by finding new uses for drugs, which have already been proven effective, for preventing or treating coronavirus disease 2019 by drug repositioning technology. The pharmaceutical composition is useful because it has significantly lower side effects than new drugs and can be rapidly applied to clinical practice.

Abstract: The present invention relates to a recombinant microorganism having enhanced ability to produce lutein and a method of producing lutein using the same, and more specifically, to a recombinant microorganism having enhanced ability to produce lutein, which is obtained by modifying any one or more metabolic pathways, selected from the group consisting of a substrate tunnel, an electron tunnel, and a C5 heme production pathway, in a host cell having ability to produce lutein. Using the highly efficient lutein-producing recombinant microbial strain according to the present invention, it is possible to replace an existing lutein production method that relies on labor-intensive and inefficient plant extraction and to produce lutein in a more environmentally friendly and sustainable way.

Abstract: The present invention relates to a recombinant microorganism imparted with increased ability to produce glutaric acid by further introducing a gene encoding a polypeptide having glutaric acid transporter activity into a microorganism having ability to produce glutaric acid, and to a method of preparing glutaric acid using the recombinant microorganism. According to the present invention, glutaric acid used for the preparation of various compounds such as polyamide, polyurethane, 1,5-pentanediol, and 5-hydroxyvaleric acid can be biosynthesized at high yield.