Patents by Inventor Sanna Leskinen

Sanna Leskinen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and DNA constructs for increasing the production level of carbohydrate degrading enzymes in filamentous fungi
    Patent number: 7348172
    Abstract: The invention is related to a method and DNA constructs for obtaining in a filamentous fungus host a higher production level of a carbohydrate degrading (CD) enzyme, having in its original state a catalytic module (CAT) and a carbohydrate binding module (CBM) separated by a linker region. The DNA construct comprising a truncated actinomycetes, preferably Nonomuraea flexuosa (NJ) derived DNA sequence encoding a truncated form of the CD enzyme, for example Nf Xyn11A, Nf Xyn10A, and is introduced into a filamentous fungal host. Said CD enzyme contains the catalytically active region of CAT but lacks part or all of the CBM, or all of the CBM and part or all of the linker region and is expressed and secreted under the control of regulatory sequences comprising at least a signal sequence, but also promoters, terminators and DNA sequences encoding a secretable carrier protein or domains thereof, preferably originating from filamentous fungi are included.
    Type: Grant
    Filed: April 18, 2005
    Date of Patent: March 25, 2008
    Assignee: AB Enzymes Oy
    Inventors: Marja Paloheimo, Arja Mantyla, Sanna Leskinen, Richard Fagerstrom, Jarno Kallio, Terhi Puranen, Raija Lantto, Pirkko Suominen
  • Method and DNA constructs for increasing the production level of carbohydrate degrading enzymes in filamentous fungi
    Publication number: 20060014247
    Abstract: The invention is related to a method and DNA constructs for obtaining in a filamentous fungus host a higher production level of a carbohydrate degrading (CD) enzyme, having in its original state a catalytic module (CAT) and a carbohydrate binding module (CBM) separated by a linker region. The DNA construct comprising a truncated actinomycetes, preferably Nonomuraea flexuosa (NJ) derived DNA sequence encoding a truncated form of the CD enzyme, for example Nf Xyn11A, Nf Xyn10A, and is introduced into a filamentous fungal host. Said CD enzyme contains the catalytically active region of CAT but lacks part or all of the CBM, or all of the CBM and part or all of the linker region and is expressed and secreted under the control of regulatory sequences comprising at least a signal sequence, but also promoters, terminators and DNA sequences encoding a secretable carrier protein or domains thereof, preferably originating from filamentous fungi are included.
    Type: Application
    Filed: April 18, 2005
    Publication date: January 19, 2006
    Inventors: Marja Paloheimo, Arja Mantyla, Sanna Leskinen, Richard Fagerstrom, Jarno Kallio, Terhi Puranen, Raija Lantto, Pirkko Suominen