Abstract: A liquid phase laser ablation apparatus is provided, which includes a vessel for storing liquid in which a component to be atomized is arranged; a laser oscillating device for oscillating a laser light irradiated to the component through the liquid; a reflecting mirror configured to freely change an angle of incidence of the laser light with respect to a surface of the liquid; a focusing lens for focusing the laser light oscillated from the laser oscillating device; a cover body for covering an upper surface of the vessel; and a laser light introduction port provided on the cover body or a side surface of the vessel above the surface of the liquid. Accordingly, liquid will not adhere to optical components constituting the apparatus, there is little contamination and damage to the optical components, and laser ablation can occur in a continuous and stable manner for a long period of time.

Abstract: The present invention provides a liquid phase laser ablation apparatus comprising: a vessel for storing liquid in which a component to be atomized is arranged; a laser oscillating device for oscillating a laser light irradiated to the component through the liquid; a reflecting mirror configured to freely change an angle of incidence of the laser light with respect to a surface of the liquid; a focusing lens for focusing the laser light oscillated from the laser oscillating device; a cover body for covering an upper surface of the vessel; and a laser light introduction port provided on the cover body or a side surface of the vessel above the surface of the liquid. Due to the above structure, the liquid would not adhere to the optical components constituting the apparatus, there is little contamination and damage to the optical components, the operation of the laser ablation can be continued in continuous and stable manner for a long period of time.

Abstract: This invention provides a drug nanoparticle 7 obtained by irradiating laser beam 3 to a solid target 2 composed of drug powder so as to release the drug as downsized component particle from the solid target 2, wherein the drug nanoparticles 7 has an average diameter of 100 nm or less. According to the above structure, there can be provided: a drug nanoparticle having a high bioavailability, a high purity and an excellent handling property in a case where the drug nanoparticle is used as medical agent, agricultural chemical (agrichemical), chemical fertilizer or the like. The method of manufacturing the drug and the medical agent manufacturing apparatus are capable of effectively manufacturing the drug nanoparticles through simple manufacturing steps.