Patents by Inventor Saori Amaike

Saori Amaike has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Promoter useful for high expression of a heterologous gene of interest in
    Patent number: 11414653
    Abstract: The present invention provides for an Aspergillus niger host cell comprising a gene of interest operatively linked to an ecm33 promoter of an ascomycete fungi, wherein the gene of interest is heterologous to the ecm33 promoter and/or to Aspergillus niger. In some embodiments, the gene of interest is a glycoside hydrolase enzyme. In some embodiments, the glycoside hydrolase enzyme is a glucosidase.
    Type: Grant
    Filed: September 6, 2018
    Date of Patent: August 16, 2022
    Assignees: National Technology & Engineering Solutions of Sandia, LLC, Battelle Memorial Institute, The Regents of the University of California
    Inventors: John M. Gladden, Saori Amaike Campen, Jinxiang Zhang, Jon K. Magnuson, Scott E. Baker, Blake A. Simmons
  • Promoter useful for high expression of a heterologous gene of interest in Aspergillus niger
    Publication number: 20190169584
    Abstract: The present invention provides for an Asperigillus niger host cell comprising a gene of interest operatively linked to an ecm33 promoter of an ascomycete fungi, wherein the gene of interest is heterologous to the ecm33 promoter and/or to Asperigillus niger. In some embodiments, the gene of interest is a glycoside hydrolase enzyme. In some embodiments, the glycoside hydrolase enzyme is a glucosidase.
    Type: Application
    Filed: September 6, 2018
    Publication date: June 6, 2019
    Applicant: The Regents of the University of California
    Inventors: John M. Gladden, Saori Amaike Campen, Jinxiang Zhang, Jon K. Magnuson, Scott E. Baker, Blake A. Simmons
  • Over-production of secondary metabolites by over-expression of the VEA gene
    Patent number: 9428770
    Abstract: The invention provides a general and facile method to obtain secondary metabolites from fungal sources. The invention is based on the discovery that the fungal gene veA and protein encoded thereby regulates the activity of multiple secondary metabolite gene clusters in fungi. Over expression of the gene veA provides increased production of secondary metabolites in engineered cells. In particular, such a method of increasing secondary metabolite production allows the production of improved yields of valuable secondary metabolite products.
    Type: Grant
    Filed: September 15, 2014
    Date of Patent: August 30, 2016
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Nancy P. Keller, Saori Amaike Campen
  • Over-Production of Secondary Metabolites by Over-Expression of the VEA Gene
    Publication number: 20150037862
    Abstract: The invention provides a general and facile method to obtain secondary metabolites from fungal sources. The invention is based on the discovery that the fungal gene veA and protein encoded thereby regulates the activity of multiple secondary metabolite gene clusters in fungi. Over expression of the gene veA provides increased production of secondary metabolites in engineered cells. In particular, such a method of increasing secondary metabolite production allows the production of improved yields of valuable secondary metabolite products.
    Type: Application
    Filed: September 15, 2014
    Publication date: February 5, 2015
    Inventors: NANCY P. KELLER, SAORI AMAIKE
  • Over-production of secondary metabolites by over-expression of the VEA gene
    Patent number: 8871494
    Abstract: The invention provides a general and facile method to obtain secondary metabolites from fungal sources. The invention is based on the discovery that the fungal gene veA and protein encoded thereby regulates the activity of multiple secondary metabolite gene clusters in fungi. Over expression of the gene veA provides increased production of secondary metabolites in engineered cells. In particular, such a method of increasing secondary metabolite production allows the production of improved yields of valuable secondary metabolite products.
    Type: Grant
    Filed: April 26, 2010
    Date of Patent: October 28, 2014
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Nancy P. Keller, Saori Amaike
  • Over-production of secondary metabolites by over-expression of the VEA gene
    Publication number: 20110076682
    Abstract: The invention provides a general and facile method to obtain secondary metabolites from fungal sources. The invention is based on the discovery that the fungal gene veA and protein encoded thereby regulates the activity of multiple secondary metabolite gene clusters in fungi. Over expression of the gene veA provides increased production of secondary metabolites in engineered cells. In particular, such a method of increasing secondary metabolite production allows the production of improved yields of valuable secondary metabolite products.
    Type: Application
    Filed: April 26, 2010
    Publication date: March 31, 2011
    Applicant: Wisconsin Alumni Research Foundation
    Inventors: Nancy P. Keller, Saori Amaike