Patents by Inventor Sara Coppens

Sara Coppens has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant virus products and methods for inhibition of expression of DUX4
    Patent number: 11802291
    Abstract: The present invention relates to RNA interference-based methods for inhibiting the expression of the DUX4 gene, a double homeobox gene on human chromosome 4q35. Recombinant adeno-associated viruses of the invention deliver DNAs encoding microRNAs that knock down the expression of DUX4. The methods have application in the treatment of muscular dystrophies such as facioscapulohumeral muscular dystrophy.
    Type: Grant
    Filed: March 12, 2019
    Date of Patent: October 31, 2023
    Assignee: RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL
    Inventors: Scott Quenton Harper, Jian Liu, Sara Coppens, Lindsay Wallace
  • RECOMBINANT VIRUS PRODUCTS AND METHODS FOR INHIBITION OF EXPRESSION OF DUX4
    Publication number: 20190300903
    Abstract: The present invention relates to RNA interference-based methods for inhibiting the expression of the DUX4 gene, a double homeobox gene on human chromosome 4q35. Recombinant adeno-associated viruses of the invention deliver DNAs encoding microRNAs that knock down the expression of DUX4. The methods have application in the treatment of muscular dystrophies such as facioscapulohumeral muscular dystrophy.
    Type: Application
    Filed: March 12, 2019
    Publication date: October 3, 2019
    Inventors: Scott Quenton Harper, Jian Liu, Sara Coppens, Lindsay Wallace
  • Recombinant virus products and methods for inhibition of expression of DUX4
    Patent number: 10301649
    Abstract: The present invention relates to RNA interference-based methods for inhibiting the expression of the DUX4 gene, a double homeobox gene on human chromosome 4q35. Recombinant adeno-associated viruses of the invention deliver DNAs encoding microRNAs that knock down the expression of DUX4. The methods have application in the treatment of muscular dystrophies such as facioscapulohumeral muscular dystrophy.
    Type: Grant
    Filed: October 17, 2016
    Date of Patent: May 28, 2019
    Assignee: NATIONWIDE CHILDREN'S HOSPITAL, INC.
    Inventors: Scott Quenton Harper, Jian Liu, Sara Coppens, Lindsay Wallace
  • RECOMBINANT VIRUS PRODUCTS AND METHODS FOR INHIBITION OF EXPRESSION OF DUX4
    Publication number: 20170029849
    Abstract: The present invention relates to RNA interference-based methods for inhibiting the expression of the DUX4 gene, a double homeobox gene on human chromosome 4q35. Recombinant adeno-associated viruses of the invention deliver DNAs encoding microRNAs that knock down the expression of DUX4. The methods have application in the treatment of muscular dystrophies such as facioscapulohumeral muscular dystrophy.
    Type: Application
    Filed: October 17, 2016
    Publication date: February 2, 2017
    Inventors: Scott Quenton Harper, Jian Liu, Sara Coppens, Lindsay Wallace