Patents by Inventor Sarika Gupta

Sarika Gupta has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS USEFUL FOR THE TREATMENT OF INFLAMMATORY DISEASE OR DISORDERS
    Publication number: 20140170108
    Abstract: The present invention provides sustained release and long acting forms of peptide therapeutic, particularly Interleukin-1 receptor antagonist (IL-1ra), including multimeric forms of IL-1ra, including variants of IL-1ra which are capable of multimerising, and compositions comprising the long acting and multimeric forms of IL-1ra, and a process of preparation thereof. The present invention also provides compositions comprising the multimeric forms of IL-1ra, including IL-1raK, KIL-1ra and KIL-1raK, which are effective in inhibiting, treating and/or ameliorating rheumatoid disease, inflammatory diseases or disorders, autoinflammatory disorders or conditions resulting from adverse effects of Interleukin-1 (IL-1). Methods of treating a subject comprising administering the composition comprising the multimeric forms of IL-1ra are also provided.
    Type: Application
    Filed: May 18, 2012
    Publication date: June 19, 2014
    Inventors: Avadhesha Surolia, Shweta Pasi, Sarika Gupta
  • COMPOSITIONS FOR THE TREATMENT OF DIABETES
    Publication number: 20130217621
    Abstract: A supramolecular insulin assembly and supramolecular exendin-4 assembly, which is useful as a protein therapeutic agent for the treatment of metabolic disorders particularly diabetes. The supramolecular assemblies disclosed in the present invention consists of insoluble and aggregated oligomers the protein. The invention also provides pharmaceutical compositions comprising the supramolecular assembly.
    Type: Application
    Filed: March 18, 2013
    Publication date: August 22, 2013
    Inventors: Avadhesha Surolia, Sarika Gupta, Mahendra Pal Singh, Tandrika Chattopadhyay
  • Compositions comprising SIA for the treatment of diabetes
    Patent number: 8426362
    Abstract: A supramolecular insulin assembly and supramolecular exendin-4 assembly, which is useful as a protein therapeutic agent for the treatment of metabolic disorders particularly diabetes. The supramolecular assemblies disclosed in the present invention consists of insoluble and aggregated oligomers the protein. The invention also provides pharmaceutical compositions comprising the supramolecular assembly.
    Type: Grant
    Filed: April 7, 2009
    Date of Patent: April 23, 2013
    Assignees: National Institute of Immunology, Indian Institute of Science
    Inventors: Avadhesha Surolia, Sarika Gupta, Mahendra Pal Singh, Tandrika Chattopadhyay
  • Compositions Useful for the Treatment of Diabetes and Other Chronic Disorder
    Publication number: 20110034385
    Abstract: The present invention provides a supramolecular protein assembly useful as a protein therapeutics for the treatment of metabolic disorders particularly diabetes. The supramolecular protein assembly disclosed in the present invention consists of insoluble and aggregated oligomers the protein. The invention also provides pharmaceutical compositions comprising supramolecular protein assembly. The composition disclosed in the present invention particularly comprises supramolecular insulin assembly.
    Type: Application
    Filed: October 13, 2008
    Publication date: February 10, 2011
    Applicants: NATIONAL INSTITUTE OF IMMUNOLOGY, INDIAN INSTITUTE OF SCIENCE
    Inventors: Avadhesha Surolia, Sarika Gupta, Mahendra Singh, Tandrika Chattopadhyay
  • Compositions For the Treatment of Diabetes
    Publication number: 20090258818
    Abstract: A supramolecular insulin assembly and supramolecular exendin-4 assembly, which is useful as a protein therapeutic agent for the treatment of metabolic disorders particularly diabetes. The supramolecular assemblies disclosed in the present invention consists of insoluble and aggregated oligomers the protein. The invention also provides pharmaceutical compositions comprising the supramolecular assembly.
    Type: Application
    Filed: April 7, 2009
    Publication date: October 15, 2009
    Applicants: National Institute of Immunology, Indian Institute of Science
    Inventors: Avadhesha Surolia, Sarika Gupta, Mahendra Pal Singh, Tandrika Chattopadhyay