Patents by Inventor Sarita Nethula

Sarita Nethula has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9491966
    Abstract: The present invention is directed to polyphenolic polymers formed from dihydroxybenzoic acid (DHB) derivatives or from resorcinol derivatives, monomers which form such polymers, blends of the polymers with drugs and/or additional polymers, as well as medical devices formed from, coated with, impregnated by or coverings made with any of the foregoing polymers (with or without drugs) or blends (with or without drugs).
    Type: Grant
    Filed: May 2, 2008
    Date of Patent: November 15, 2016
    Assignee: TYRX, Inc.
    Inventors: Arikha Moses, Satish Pulapura, Qing Ge, Sarita Nethula, Archana Rajaram
  • Patent number: 9233192
    Abstract: The present invention relates to polymers modified to increase their resorbability. In particular, the polymers of the invention have phenyl ester side chains which are good leaving groups and which thereby increase the resorption rate of the polymer relative to the same polymer, for example, bearing a comparable amount of an alkyl ester side chain. Such polymers are generally water insoluble, but when modified are able to solubilize drugs and upon degradation and resorption, release those in a physiological environment in a controlled and/or sustained manner.
    Type: Grant
    Filed: November 26, 2013
    Date of Patent: January 12, 2016
    Assignee: TYRX, INC.
    Inventors: Arthur Schwartz, Satish Pulapura, Sarita Nethula
  • Patent number: 9127124
    Abstract: The present invention is directed to linear, biodegradable polyesteramide (PEA) polymers synthesized with repeating units derived from aminophenol esters and diacids. These PEAs have a monomer repeat represented by as well as a variety of uses to coat, form or comprise medical devices, combination medical devices and pharmaceutical compositions, including sustained release formulations.
    Type: Grant
    Filed: September 19, 2014
    Date of Patent: September 8, 2015
    Assignee: TYRX, INC.
    Inventors: Arthur Schwartz, Satish Pulapura, Sarita Nethula, Archana Rajaram, Arikha Moses
  • Patent number: 8952106
    Abstract: The present invention is directed to linear, biodegradable polyesteramide (PEA) polymers synthesized with repeating units derived from aminophenol esters and diacids. These PEAs have a monomer repeat represented by as well as a variety of uses to coat, form or comprise medical devices, combination medical devices and pharmaceutical compositions, including sustained release formulations.
    Type: Grant
    Filed: February 13, 2013
    Date of Patent: February 10, 2015
    Assignee: TYRX, Inc.
    Inventors: Arthur Schwartz, Satish Pulapura, Sarita Nethula, Archana Rajaram, Arikha Moses
  • Publication number: 20150004212
    Abstract: The present invention is directed to linear, biodegradable polyesteramide (PEA) polymers synthesized with repeating units derived from aminophenol esters and diacids. These PEAs have a monomer repeat represented by as well as a variety of uses to coat, form or comprise medical devices, combination medical devices and pharmaceutical compositions, including sustained release formulations.
    Type: Application
    Filed: September 19, 2014
    Publication date: January 1, 2015
    Inventors: Arthur Schwartz, Satish Pulapura, Sarita Nethula, Archana Rajaram, Arikha Moses
  • Patent number: 8911765
    Abstract: A biodegradable, flexible covering for a breast implant is provided which comprises one or more biodegradable polymer layers dimensioned and shaped to cover at least a portion of the breast implant. The implant can be inserted into an opening of the covering immediately prior to surgery, but alternate configurations and times of insertion are contemplated as well as open or sheet type devices. The coverings can optionally contain one or more drugs for delivery at the surgical site, particularly for treating or preventing infection, pain, inflammation, capsular contracture, scarring or other complications associated with breast augmentation or breast reconstruction.
    Type: Grant
    Filed: March 28, 2008
    Date of Patent: December 16, 2014
    Assignee: Tyrx, Inc.
    Inventors: Arikha Moses, Satish Pulapura, Qing Ge, Sarita Nethula, Irene Shatova, Archana Rajaram
  • Publication number: 20140079760
    Abstract: The present invention relates to polymers modified to increase their resorbability. In particular, the polymers of the invention have phenyl ester side chains which are good leaving groups and which thereby increase the resorption rate of the polymer relative to the same polymer, for example, bearing a comparable amount of an alkyl ester side chain. Such polymers are generally water insoluble, but when modified are able to solubilize drugs and upon degradation and resorption, release those in a physiological environment in a controlled and/or sustained manner.
    Type: Application
    Filed: November 26, 2013
    Publication date: March 20, 2014
    Applicant: TYRX Pharma, Inc.
    Inventors: Arthur Schwartz, Satish Pulapura, Sarita Nethula
  • Patent number: 8629233
    Abstract: The present invention relates to polymers modified to increase their resorbability. In particular, the polymers of the invention have phenyl ester side chains which are good leaving groups and which thereby increase the resorption rate of the polymer relative to the same polymer, for example, bearing a comparable amount of an alkyl ester side chain. Such polymers are generally water insoluble, but when modified are able to solublize drugs and upon degradation and resorption, release those in a physiological environment in a controlled and/or sustained manner.
    Type: Grant
    Filed: December 18, 2009
    Date of Patent: January 14, 2014
    Assignee: TYRX, Inc.
    Inventors: Arthur Schwartz, Satish Pulapura, Sarita Nethula
  • Patent number: 8445603
    Abstract: The present invention is directed to linear, biodegradable polyesteramide (PEA) polymers synthesized with repeating units derived from aminophenol esters and diacids. These PEAs have a monomer repeat represented by as well as a variety of uses to coat, form or comprise medical devices, combination medical devices and pharmaceutical compositions, including sustained release formulations.
    Type: Grant
    Filed: September 22, 2009
    Date of Patent: May 21, 2013
    Assignee: TYRX, Inc.
    Inventors: Arthur Schwartz, Satish Pulapura, Sarita Nethula, Archana Rajaram, Arikha Moses
  • Publication number: 20100167992
    Abstract: The present invention relates to polymers modified to increase their resorbability. In particular, the polymers of the invention have phenyl ester side chains which are good leaving groups and which thereby increase the resorption rate of the polymer relative to the same polymer, for example, bearing a comparable amount of an alkyl ester side chain. Such polymers are generally water insoluble, but when modified are able to solublize drugs and upon degradation and resorption, release those in a physiological environment in a controlled and/or sustained manner.
    Type: Application
    Filed: December 18, 2009
    Publication date: July 1, 2010
    Inventors: Arthur Schwartz, Satish Pulapura, Sarita Nethula
  • Publication number: 20100129417
    Abstract: The present invention is directed to polyphenolic polymers formed from dihydroxybenzoic acid (DHB) derivatives or from resorcinol derivatives, monomers which form such polymers, blends of the polymers with drugs and/or additional polymers, as well as medical devices formed from, coated with, impregnated by or coverings made with any of the foregoing polymers (with or without drugs) or blends (with or without drugs).
    Type: Application
    Filed: May 2, 2008
    Publication date: May 27, 2010
    Inventors: Arikha Moses, Satish Pulapura, Qing Ge, Sarita Nethula, Archana Rajaram
  • Publication number: 20100074940
    Abstract: The present invention is directed to linear, biodegradable polyesteramide (PEA) polymers synthesized with repeating units derived from aminophenol esters and diacids. These PEAs have a monomer repeat represented by as well as a variety of uses to coat, form or comprise medical devices, combination medical devices and pharmaceutical compositions, including sustained release formulations.
    Type: Application
    Filed: September 22, 2009
    Publication date: March 25, 2010
    Inventors: Arthur Schwartz, Satish Pulapura, Sarita Nethula, Archana Rajaram, Arikha Moses
  • Publication number: 20080241212
    Abstract: A biodegradable, flexible covering for a breast implant is provided which comprises one or more biodegradable polymer layers dimensioned and shaped to cover at least a portion of the breast implant. The implant can be inserted into an opening of the covering immediately prior to surgery, but alternate configurations and times of insertion are contemplated as well as open or sheet type devices. The coverings can optionally contain one or more drugs for delivery at the surgical site, particularly for treating or preventing infection, pain, inflammation, capsular contracture, scarring or other complications associated with breast augmentation or breast reconstruction.
    Type: Application
    Filed: March 28, 2008
    Publication date: October 2, 2008
    Applicant: TYRX PHARMA, INC.
    Inventors: Arikha Moses, Satish Pulapura, Qing Ge, Sarita Nethula, Irene Shatova, Archana Rajaram