Patents by Inventor Saroja Ramanujan

Saroja Ramanujan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DOSING FOR TREATMENT WITH ANTI-CD20/ANTI-CD3 BISPECIFIC ANTIBODIES
    Publication number: 20240132613
    Abstract: The invention provides methods of dosing for the treatment of cancers, such as B cell proliferative disorders, with anti-cluster of differentiation 20 (CD20)/anti-cluster of differentiation 3 (CD3) bispecific antibodies.
    Type: Application
    Filed: December 6, 2023
    Publication date: April 25, 2024
    Inventors: Yu-Waye CHU, Iraj HOSSEINI, Saroja RAMANUJAN, Kapil GADKAR, Chi-Chung LI
  • Anti-tryptase antibodies, compositions thereof, and uses thereof
    Patent number: 11939396
    Abstract: The invention provides compositions including anti-tryptase antibodies and pharmaceutical compositions thereof, as well as methods of using the same.
    Type: Grant
    Filed: June 30, 2020
    Date of Patent: March 26, 2024
    Assignee: Genentech, Inc.
    Inventors: Xiaocheng Chen, Mark Dennis, Janet Jackman, James T. Koerber, Mason Lu, Henry R. Maun, Kathila Rajapaksa, Saroja Ramanujan, Tracy Staton, Lawren Wu, Tangsheng Yi
  • DOSING FOR TREATMENT WITH ANTI-CD20/ANTI-CD3 BISPECIFIC ANTIBODIES
    Publication number: 20230242659
    Abstract: The invention provides methods of dosing for the treatment of cancers, such as B cell proliferative disorders, with anti-cluster of differentiation 20 (CD20)/anti-cluster of differentiation 3 (CD3) bispecific antibodies.
    Type: Application
    Filed: February 23, 2023
    Publication date: August 3, 2023
    Inventors: Yu-Waye Chu, Iraj Hosseini, Saroja Ramanujan, Kapil Gadkar, Chi-Chung Li
  • Dosing for treatment with anti-CD20/anti-CD3 bispecific antibodies
    Patent number: 11466094
    Abstract: The invention provides methods of dosing for the treatment of cancers, such as B cell proliferative disorders, with anti-cluster of differentiation 20 (CD20)/anti-cluster of differentiation 3 (CD3) bispecific antibodies.
    Type: Grant
    Filed: November 15, 2017
    Date of Patent: October 11, 2022
    Assignee: Genentech, Inc.
    Inventors: Yu-Waye Chu, Iraj Hosseini, Saroja Ramanujan, Kapil Gadkar, Chi-Chung Li
  • ANTI-TRYPTASE ANTIBODIES, COMPOSITIONS THEREOF, AND USES THEREOF
    Publication number: 20200325248
    Abstract: The invention provides compositions including anti-tryptase antibodies and pharmaceutical compositions thereof, as well as methods of using the same.
    Type: Application
    Filed: June 30, 2020
    Publication date: October 15, 2020
    Inventors: Xiaocheng CHEN, Mark DENNIS, Janet JACKMAN, James T. KOERBER, Mason LU, Henry R. MAUN, Kathila RAJAPAKSA, Saroja RAMANUJAN, Tracy STATON, Lawren WU, Tangsheng YI
  • Anti-tryptase antibodies, compositions thereof, and uses thereof
    Patent number: 10752703
    Abstract: The invention provides compositions including anti-tryptase antibodies and pharmaceutical compositions thereof, as well as methods of using the same.
    Type: Grant
    Filed: August 19, 2019
    Date of Patent: August 25, 2020
    Assignee: Genentech, Inc.
    Inventors: Xiaocheng Chen, Mark Dennis, Janet Jackman, James T. Koerber, Mason Lu, Henry R. Maun, Kathila Rajapaksa, Saroja Ramanujan, Tracy Staton, Lawren Wu, Tangsheng Yi
  • Anti-tryptase antibodies, compositions thereof, and uses thereof
    Patent number: 10738131
    Abstract: The invention provides compositions including anti-tryptase antibodies and pharmaceutical compositions thereof, as well as methods of using the same.
    Type: Grant
    Filed: February 9, 2018
    Date of Patent: August 11, 2020
    Assignee: Genentech, Inc.
    Inventors: Xiaocheng Chen, Mark Dennis, Janet Jackman, James T. Koerber, Mason Lu, Henry R. Maun, Kathila Rajapaksa, Saroja Ramanujan, Tracy Staton, Lawren Wu, Tangsheng Yi
  • ANTI-TRYPTASE ANTIBODIES, COMPOSITIONS THEREOF, AND USES THEREOF
    Publication number: 20190367637
    Abstract: The invention provides compositions including anti-tryptase antibodies and pharmaceutical compositions thereof, as well as methods of using the same.
    Type: Application
    Filed: August 19, 2019
    Publication date: December 5, 2019
    Inventors: Xiaocheng CHEN, Mark DENNIS, Janet JACKMAN, James T. KOERBER, Mason LU, Henry R. MAUN, Kathila RAJAPAKSA, Saroja RAMANUJAN, Tracy STATON, Lawren WU, Tangsheng YI
  • ANTI-TRYPTASE ANTIBODIES, COMPOSITIONS THEREOF, AND USES THEREOF
    Publication number: 20180230233
    Abstract: The invention provides compositions including anti-tryptase antibodies and pharmaceutical compositions thereof, as well as methods of using the same.
    Type: Application
    Filed: February 9, 2018
    Publication date: August 16, 2018
    Inventors: Xiaocheng CHEN, Mark DENNIS, Janet JACKMAN, James T. KOERBER, Mason LU, Henry R. MAUN, Kathila RAJAPAKSA, Saroja RAMANUJAN, Tracy STATON, Lawren WU, Tangsheng YI
  • DOSING FOR TREATMENT WITH ANTI-CD20/ANTI-CD3 BISPECIFIC ANTIBODIES
    Publication number: 20180134798
    Abstract: The invention provides methods of dosing for the treatment of cancers, such as B cell proliferative disorders, with anti-cluster of differentiation 20 (CD20)/anti-cluster of differentiation 3 (CD3) bispecific antibodies.
    Type: Application
    Filed: November 15, 2017
    Publication date: May 17, 2018
    Inventors: Yu-Waye CHU, Iraj HOSSEINI, Saroja RAMANUJAN, Kapil GADKAR, Chi-Chung LI
  • METHOD AND APPARATUS FOR MODELING SKIN SENSITIZATION
    Publication number: 20100049492
    Abstract: The invention encompasses novel computer models of chemical sensitivity of skin and systems for predicting chemical sensitivity of skin. In particular, the computer model of chemical sensitivity of skin comprises a) an epidermal compartment comprising a mathematical representation of exposure of an epidermal tissue to a chemical and a mathematical representation of a first population of antigen presenting cells interacting with the chemical; and b) a lymph node compartment comprising a mathematical representation of a second population of antigen presenting cells, and a mathematical representation of a population of T cells, wherein at least a subpopulation of the population of T cells interacts with the second population of antigen presenting cells.
    Type: Application
    Filed: September 12, 2007
    Publication date: February 25, 2010
    Inventors: Seema Bajaria, Christina M. Friedrich, Katherine Kudrycki, Cameron Mackay, Thomas Paterson, Saroja Ramanujan, Gregory Shaver
  • Method and apparatus for computer modeling a joint
    Patent number: 7472050
    Abstract: The present invention relates to a mathematical and computer model of a joint. The model includes representation of the biological processes related to the synovial tissue and cartilage. In one embodiment, the model represents a human joint afflicted with rheumatoid arthritis.
    Type: Grant
    Filed: February 11, 2005
    Date of Patent: December 30, 2008
    Assignee: Entelos, Inc.
    Inventors: Nadine A. Defranoux, Todd B. Dubnicoff, David J. Klinke, II, Annette K. Lewis, Thomas S. Paterson, Saroja Ramanujan, Lisl K. M. Shoda, Karl Petter Soderstrom, Herbert K. Struemper
  • Apparatus and method for computer modeling type 1 diabetes
    Publication number: 20070071681
    Abstract: The invention encompasses novel methods for developing a computer model of type 1 diabetes in a mammal. In particular, the models can include representations of biological processes associated with a pancreatic lymph node and one or more pancreatic islets. Alternatively, the models can include representations of biological processes associated with at least two conditions selected from the group consisting of autoreactive T cell production, autoreactive T cell priming, insulitis and hyperglycemia. The invention also provides methods for developing a computer model of a non-insulin replacement treatment of type 1 diabetes. The invention also encompasses computer models of type 1 diabetes, methods of simulating type 1 diabetes and computer systems for simulating type 1 diabetes and the uses thereof.
    Type: Application
    Filed: March 15, 2006
    Publication date: March 29, 2007
    Inventors: Kapil Gadkar, Huub Kreuwel, Thomas Paterson, David Polidori, Saroja Ramanujan, Lisl Katharine Mie Shoda, Chan Whiting, Daniel Young, Yanan Zheng
  • Method and apparatus for computer modeling a joint
    Publication number: 20060058988
    Abstract: The present invention relates to a mathematical and computer model of a joint. The model includes representation of the biological processes related to the synovial tissue and cartilage. In one embodiment, the model represents a human joint afflicted with rheumatoid arthritis.
    Type: Application
    Filed: February 11, 2005
    Publication date: March 16, 2006
    Inventors: Nadine Defranoux, Todd Dubnicoff, David Klinke, Annette Lewis, Thomas Paterson, Saroja Ramanujan, Lisl Shoda, Karl Soderstrom, Herbert Struemper
  • Treatment of rheumatoid arthritis with FLIP antagonists
    Publication number: 20050208151
    Abstract: The invention encompasses novel methods of treating rheumatoid arthritis and its symptoms and novel methods of identifying and screening for drugs useful in the treatment of rheumatoid arthritis and its clinical symptoms. Targeted manipulation of a computer model of a human rheumatic joint provided the surprising result that decreasing the activity of FLIP, an inhibitor of apoptosis, by at least 25% has a significant impact on the pathophysiology of rheumatoid arthritis. Inhibition of the activity of FLIP by at least 25% is predicted to alleviate the symptoms of rheumatoid arthritis.
    Type: Application
    Filed: November 1, 2004
    Publication date: September 22, 2005
    Applicant: Entelos, Inc.
    Inventors: Vincent Hurez, Saroja Ramanujan, Lisl Shoda, Leif Wennerberg, Seth Michelson, Nadine Defranoux
  • Method and apparatus for computer modeling a joint
    Patent number: 6862561
    Abstract: The present invention relates to a mathematical and computer model of a joint. The model includes representation of the biological processes related to the synovial tissue and cartilage. In one embodiment, the model represents a human joint afflicted with rheumatoid arthritis.
    Type: Grant
    Filed: May 22, 2002
    Date of Patent: March 1, 2005
    Assignee: Entelos, Inc.
    Inventors: Nadine A. Defranoux, Todd B. Dubnicoff, David J. Klinke, II, Annette K. Lewis, Thomas S. Paterson, Saroja Ramanujan, Lisl K. M. Shoda, Karl Petter Soderstrom, Herbert K. Struemper
  • Method and apparatus for computer modeling a joint
    Publication number: 20030078759
    Abstract: The present invention relates to a mathematical and computer model of a joint. The model includes representation of the biological processes related to the synovial tissue and cartilage. In one embodiment, the model represents a human joint afflicted with rheumatoid arthritis.
    Type: Application
    Filed: May 22, 2002
    Publication date: April 24, 2003
    Inventors: Nadine A. Defranoux, Todd B. Dubnicoff, David J. Klinke, Annette K. Lewis, Thomas S. Paterson, Saroja Ramanujan, Lisl K. M. Shoda, Karl Petter Soderstrom, Herbert K. Struemper