Patents by Inventor Satoru Hatakeyama
Satoru Hatakeyama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11990846Abstract: A power conversion apparatus includes a converter circuit converting AC voltage output from an AC power supply into DC voltage. The converter circuit includes unit converters. The power conversion apparatus includes a low current-oriented controller the unit converters to cause current corresponding to a single phase to flow through a current detector, and a high current-oriented controller controlling operation of the unit converters based on a result of comparison between a duty command and a carrier signal, where the duty command is generated based on detection values detected by the current detector and a voltage detector. When the detection value detected by the current detector is less than or equal to a first threshold, the low current-oriented controller is activated, and when the detection value detected by the current detector is greater than the first threshold, the high current-oriented controller is activated.Type: GrantFiled: November 14, 2019Date of Patent: May 21, 2024Assignee: Mitsubishi Electric CorporationInventors: Motoya Suzuki, Satoru Ichiki, Keisuke Uemura, Koichi Arisawa, Kazunori Hatakeyama
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Publication number: 20120289411Abstract: Provided is a method for screening a library of candidate for a nucleic acid ligand. The method includes the steps of: (a) preparing a library of candidate of nucleic acid ligands; (b) contacting, under the absence of a target substance, the library with a supporting member binding to at least one of conserved sequence domains included in the ligand, and then separating and removing a ligand which does not form an intermolecular duplex; and (c) dissociating the intermolecular duplex by contacting, under the presence of the target substance, the target substance with the remaining ligand forming the intermolecular duplex obtained in step (b), and then separating and collecting a ligand having a specific secondary structure formed by the binding to the target substance, wherein the method includes at least one time of step (b) and at least one time of step (c).Type: ApplicationFiled: February 23, 2011Publication date: November 15, 2012Applicant: CANON KABUSHIKI KAISHAInventors: Satoru Hatakeyama, Takahisa Ibii
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Patent number: 8183058Abstract: It is intended to provide a target substance detection element wherein a target substance capturing body for capturing target substances is immobilized with good orientation in a desired region on the surface of the target substance detection element, a method for producing the target substance detection element, and a detection method using the target substance detection element.Type: GrantFiled: March 17, 2008Date of Patent: May 22, 2012Assignee: Canon Kabushiki KaishaInventors: Satoru Hatakeyama, Takashi Ikeda
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Patent number: 8084214Abstract: The present invention intends to provide a high sensitivity method for identifying the type of a protein contained in each cell with a diameter of ten to several tens ?m and a sample treatment solution required for it. The above is achieved by three steps of (1) treating a slice of a diseased tissue with an aqueous solution containing gold particles and a digestive enzyme, and digesting restrictively a protein of interest, (2) measuring a 2-dimensional distribution of fragmented peptides by TOF-SIMS, and (3) visualizing a 2-dimensional distribution of the target protein in the slice of the diseased tissue using the results of the proteome analysis and by means of a numerical analysis.Type: GrantFiled: April 7, 2008Date of Patent: December 27, 2011Assignee: Canon Kabushiki KaishaInventors: Hiroyuki Hashimoto, Manabu Komatsu, Satoru Hatakeyama
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Publication number: 20110212842Abstract: The present invention provides a method for screening for a ligand having an affinity for a target substance and having readiness for conformational change forming a desired conformation upon binding to a target substance. The method includes the steps of (a) contacting a first mixture of candidate ligands with a carrier, followed by separating and collecting, as a second mixture of candidate ligands, a mixture of free candidate ligands not bound to the carrier, (b) contacting the second mixture of candidate ligands with the target substance, and (c) contacting the carrier with a solution containing the target substance and the mixture of candidate ligands obtained in step (b), and then separating and enriching a ligand, at least a part of which forms the particular conformation.Type: ApplicationFiled: February 8, 2011Publication date: September 1, 2011Applicant: CANON KABUSHIKI KAISHAInventors: Takahisa Ibii, Satoru Hatakeyama
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Patent number: 7989219Abstract: A capturing molecule having an association containing a plurality of polypeptide chains that specifically bind to different sites of a target substance, characterized in that each of the polypeptide chains has a domain having a hypervariable loop structure at a binding site binding to the target substance and an association portion for forming the association, and the polypeptide chains are associated via the association portions present in the polypeptide chains.Type: GrantFiled: May 30, 2006Date of Patent: August 2, 2011Assignee: Canon Kabushiki KaishaInventors: Hidenori Shiotsuka, Satoru Hatakeyama, Tsuyoshi Nomoto, Masaru Kaieda, Junta Yamamichi
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Patent number: 7875465Abstract: A capturing molecule having not less than two domains specifically binding to different sites of a target substance, wherein the not less than two domains comprise (1) a first domain having a hypervariable loop structure at a binding site to the target substance, and (2) a second domain having no hypervariable loop structure at a binding site to the target substance.Type: GrantFiled: May 29, 2006Date of Patent: January 25, 2011Assignee: Canon Kabushiki KaishaInventors: Hidenori Shiotsuka, Satoru Hatakeyama, Tsuyoshi Nomoto, Masaru Kaieda, Junta Yamamichi
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Patent number: 7868142Abstract: It is intended to provide an anti-photocrosslinking group antibody capable of specifically binding to a photocrosslinking group and available in the binding of a substrate and a substance of interest in a microstructure, a complex protein including at least the antibody or at least a portion thereof, and a technique for use thereof in the detection of a target substance. The present invention provides a protein having at least the structure of an antibody that recognizes a photocrosslinking group.Type: GrantFiled: October 9, 2007Date of Patent: January 11, 2011Assignee: Canon Kabushiki KaishaInventors: Satoru Hatakeyama, Takeshi Imamura, Hidenori Shiotsuka
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Publication number: 20100047928Abstract: It is intended to provide a target substance detection element wherein a target substance capturing body for capturing target substances is immobilized with good orientation in a desired region on the surface of the target substance detection element, a method for producing the target substance detection element, and a detection method using the target substance detection element.Type: ApplicationFiled: March 17, 2008Publication date: February 25, 2010Applicant: CANON KABUSHIKI KAISHAInventors: Satoru Hatakeyama, Takashi Ikeda
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Publication number: 20090215197Abstract: A capturing molecule having not less than two domains specifically binding to different sites of a target substance, wherein the not less than two domains comprise (1) a first domain having a hypervariable loop structure at a binding site to the target substance, and (2) a second domain having no hypervariable loop structure at a binding site to the target substance.Type: ApplicationFiled: May 29, 2006Publication date: August 27, 2009Applicant: CANON KABUSHIKI KAISHAInventors: Hidenori Shiotsuka, Satoru Hatakeyama, Tsuyoshi Nomoto, Masaru Kaieda, Junta Yamamichi
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Publication number: 20090170220Abstract: A capturing molecule having an association containing a plurality of polypeptide chains that specifically bind to different sites of a target substance, characterized in that each of the polypeptide chains has a domain having a hypervariable loop structure at a binding site binding to the target substance and an association portion for forming the association, and the polypeptide chains are associated via the association portions present in the polypeptide chains.Type: ApplicationFiled: May 30, 2006Publication date: July 2, 2009Applicant: CANON KABUSHIKI KAISHAInventors: Hidenori Shiotsuka, Satoru Hatakeyama, Tsuyoshi Nomoto, Masaru Kaieda, Junta Yamamichi
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Patent number: 7541195Abstract: The substrate for biomolecule microarray has one or more spots for immobilizing a biomolecule. The spot for immobilizing a biomolecule protrudes from the surface of the substrate and has a flat surface for spotting on the top thereof, at least the surface of the substrate around the protruding spot part, the lateral surface of the protruding spot part and the flat surface for spotting are comprised of an electrically conductive substance. Alternatively, the spot for immobilizing a biomolecule protrudes from the surface of the substrate and has a flat surface for spotting on the top thereof, the protruding spot parts adjacent each other border through the lateral surface of the protruding spot part, and at least the lateral surface of the protruding spot part and the flat surface for spotting are comprised of an electrically conductive substance.Type: GrantFiled: June 9, 2004Date of Patent: June 2, 2009Assignee: RikenInventors: Hideo Tashiro, Yasumitsu Kondoh, Tokuji Kitsunai, Satoru Hatakeyama
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Patent number: 7465579Abstract: A device for introducing fine magnetic particles into a cell by applying an electric field to a reaction field where a sample solution containing cells and the fine magnetic particles are introduced, in order to form pores in the surface of the cell, and then applying a magnetic field to the reaction field to introduce the fine magnetic particles into the cell through the pore(s).Type: GrantFiled: June 24, 2005Date of Patent: December 16, 2008Assignee: Canon Kabushiki KaishaInventors: Satoru Hatakeyama, Hideaki Okamoto, Norihiko Utsunomiya, Junta Yamamichi
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Publication number: 20080268497Abstract: The present invention intends to provide a high sensitivity method for identifying the type of a protein contained in each cell with a diameter of ten to several tens ?m and a sample treatment solution required for it. The above is achieved by three steps of (1) treating a slice of a diseased tissue with an aqueous solution containing gold particles and a digestive enzyme, and digesting restrictively a protein of interest, (2) measuring a 2-dimensional distribution of fragmented peptides by TOF-SIMS, and (3) visualizing a 2-dimensional distribution of the target protein in the slice of the diseased tissue using the results of the proteome analysis and by means of a numerical analysis.Type: ApplicationFiled: April 7, 2008Publication date: October 30, 2008Applicant: CANON KABUSHIKI KAISHAInventors: Hiroyuki Hashimoto, Manabu Komatsu, Satoru Hatakeyama
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Publication number: 20080187461Abstract: It is intended to provide an anti-photocrosslinking group antibody capable of specifically binding to a photocrosslinking group and available in the binding of a substrate and a substance of interest in a microstructure, a complex protein including at least the antibody or at least a portion thereof, and a technique for use thereof in the detection of a target substance. The present invention provides a protein having at least the structure of an antibody that recognizes a photocrosslinking group.Type: ApplicationFiled: October 9, 2007Publication date: August 7, 2008Applicant: CANON KABUSHIKI KAISHAInventors: Satoru Hatakeyama, Takeshi Imamura, Hidenori Shiotsuka
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Publication number: 20070037155Abstract: The substrate for biomolecule microarray has one or more spots for immobilizing a biomolecule. The spot for immobilizing a biomolecule protrudes from the surface of the substrate and has a flat surface for spotting on the top thereof, at least the surface of the substrate around the protruding spot part, the lateral surface of the protruding spot part and the flat surface for spotting are comprised of an electrically conductive substance. Alternatively, the spot for immobilizing a biomolecule protrudes from the surface of the substrate and has a flat surface for spotting on the top thereof, the protruding spot parts adjacent each other border through the lateral surface of the protruding spot part, and at least the lateral surface of the protruding spot part and the flat surface for spotting are comprised of an electrically conductive substance.Type: ApplicationFiled: June 9, 2004Publication date: February 15, 2007Applicant: RIKENInventors: Hideo Tashiro, Yasumitsu Kondoh, Tokuji Kitsunai, Satoru Hatakeyama
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Publication number: 20070004019Abstract: A device for introducing fine magnetic particles into a cell by applying an electric field to a reaction field where a sample solution containing cells and the fine magnetic particles are introduced, in order to form pores in the surface of the cell, and then applying a magnetic field to the reaction field to introduce the fine magnetic particles into the cell through the pore(s).Type: ApplicationFiled: June 24, 2005Publication date: January 4, 2007Applicant: CANON KABUSHIKI KAISHAInventors: Satoru Hatakeyama, Hideaki Okamoto, Norihiko Utsunomiya, Junta Yamamichi
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Publication number: 20060275811Abstract: A combination of polypeptide chains used as a plurality of target substance-binding domains are selected by: (1) reacting a target substance with a first polypeptide chain with a known target substance-binding domain to obtain a first complex; (2) reacting the first complex with a second polypeptide chain library composed of polypeptide chains each having a site to be associated with the first polypeptide chain to obtain second complexes in which the second polypeptide chain is bonded with the target substance in the first complex; (3) washing the second complexes to obtain a third complex in which the first polypeptide chain and the second polypeptide chain are associated with each other and bonded with the target substance; and (4) obtaining a nucleic acid sequence of the second polypeptide chain from the third complex.Type: ApplicationFiled: June 1, 2006Publication date: December 7, 2006Applicant: Canon Kabushiki KaishaInventors: Satoru Hatakeyama, Hidenori Shiotsuka, Tsuyoshi Nomoto, Masaru Kaieda