Patents by Inventor Satoshi Yonehara
Satoshi Yonehara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8670878Abstract: Portable equipment for displaying a vehicle page, indicative of information relating to a vehicle corresponding to the portable equipment, on a screen of a display unit, includes: a reading request receiving device that receives a reading request manipulation for requesting to display the vehicle page; a position information acquisition device that acquires position information of the portable equipment and the vehicle; an item selection device that specifies an area, in which the position of the portable equipment and the vehicle is disposed, and selects an item of a top page of the display unit according to the area among multiple items; and a page display controller that controls the display unit to display the item of the top page on the screen.Type: GrantFiled: March 12, 2013Date of Patent: March 11, 2014Assignee: Denso CorporationInventor: Satoshi Yonehara
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Patent number: 8637275Abstract: A new method of diagnosing postprandial hyperglycemia by indirectly measuring a blood glucose level is provided. Postprandial hyperglycemia is detected by measuring a glycation degree of lysine in hemoglobin, in which a side chain amino group of lysine is glycated (GHbLys %). Measurement of GHbLys % can be performed by cleaving hemoglobin by protease, treating a glycated part of a lysine residue in the obtained cleavage product of hemoglobin with fructosyl amino acid oxidase, and measuring a redox reaction between the glycated part and fructosyl amino acid oxidase.Type: GrantFiled: August 10, 2007Date of Patent: January 28, 2014Assignee: ARKRAY, Inc.Inventors: Satoshi Yonehara, Toshihiro Imai
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Publication number: 20130244264Abstract: A method for measuring an analyte is described that includes the steps of: i) preparing a reagent (D) in which an enzyme (A) and an enzyme (B) coexist in the absence of the analyte; ii) bringing the analyte into contact with the enzyme (A) and the enzyme (B) so that the enzyme (A) acts on the analyte to produce a product (E), on which the enzyme (B) does not substantially act, from the analyte; iii) producing a product (C) by allowing the enzyme (A) or an enzyme (F) that is different from the enzyme (A) that acts on the analyte to produce a product (C) to act on the analyte and/or the product (E); and iv) detecting the product (C) by the enzyme (B).Type: ApplicationFiled: March 11, 2013Publication date: September 19, 2013Applicants: KIKKOMAN BIOCHEMIFA COMPANY, ARKRAY, INC.Inventors: Koji Sugiyama, Satoshi Yonehara, Kazuhiko Shimoji
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Publication number: 20130245858Abstract: Portable equipment for displaying a vehicle page, indicative of information relating to a vehicle corresponding to the portable equipment, on a screen of a display unit, includes: a reading request receiving device that receives a reading request manipulation for requesting to display the vehicle page; a position information acquisition device that acquires position information of the portable equipment and the vehicle; an item selection device that specifies an area, in which the position of the portable equipment and the vehicle is disposed, and selects an item of a top page of the display unit according to the area among multiple items; and a page display controller that controls the display unit to display the item of the top page on the screen.Type: ApplicationFiled: March 12, 2013Publication date: September 19, 2013Applicant: DENSO CORPORATIONInventor: Satoshi Yonehara
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Patent number: 8361292Abstract: The present invention provides a method for analyzing hemoglobin by capillary electrophoresis, that allows the apparatus to be smaller in size, allows a highly precise analysis to be obtained, and allows the analysis to be performed in a short period of time.Type: GrantFiled: April 23, 2008Date of Patent: January 29, 2013Assignee: ARKRAY, Inc.Inventors: Yusuke Nakayama, Satoshi Yonehara
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Patent number: 8273577Abstract: The present invention provides a phenothiazine-derivative color-measuring method that can detect a phenothiazine-derivative color even at a wavelength longer than the wavelength that exhibits maximum absorption.Type: GrantFiled: January 30, 2008Date of Patent: September 25, 2012Assignee: ARKRAY, Inc.Inventors: Satoshi Yonehara, Norio Inamura
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Patent number: 8203233Abstract: Each of the rising edges of PWM outputs is arranged for radiation noise reduction, by the assignment of suffix of output priority, by setting the rising edge of the first output at a start time of a cycle time, by evaluating an output margin at the falling edge of the first output relative to a current of the second output, by setting the rising edge of the second output in sync with the falling edge of the first output if the output margin is smaller than the current size of the second output. The same arrangement is used for subsequent outputs to totally reduce the current size in a simplified manner, thereby preventing the power loss and heat dissipation.Type: GrantFiled: January 18, 2010Date of Patent: June 19, 2012Assignee: Denso CorporationInventor: Satoshi Yonehara
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Publication number: 20120138461Abstract: The present invention provides a device that decreases deformation during manufacturing of the device, provides a firm joint without use of an adhesive, and allows chemical modification of a channel during manufacturing of the device. The device includes two joined substrates, and a concavity is formed on at least one of the opposing surfaces of the two substrates so as to make a channel, where the two substrates are joined together by a covalent bond via a crosslinking agent (A), and the crosslinking agent (A) is exposed on an inner wall surface of the channel.Type: ApplicationFiled: September 23, 2011Publication date: June 7, 2012Applicant: ARKRAY, Inc.Inventors: Koji Sugiyama, Rina Matsumi, Satoshi Yonehara
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Patent number: 8192996Abstract: A method for storing a tetrazolium compound stably is provided. The tetrazolium compound is stored in the presence of sodium azide. The tetrazolium compound (A) and the sodium azide (B) are present at a ratio (A:B) in the range from 1:0.02 to 1:6.2. Furthermore, when the tetrazolium compound is stored as a solution, the concentration of the sodium azide is in the range from 0.08 to 3.2 mmol/L and the concentration of the tetrazolium compound is in the range from 0.5 to 8 mmol/L. As the tetrazolium compound, it is preferable to use 2-(4-iodophenyl)-3-(2,4-dinitrophenyl)-5-(2,4-disulfophenyl)-2H-tetrazolium salt.Type: GrantFiled: April 1, 2009Date of Patent: June 5, 2012Assignee: Arkray, Inc.Inventors: Kaori Ishimaru, Satoshi Yonehara
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Patent number: 8137512Abstract: A process for analyzing a sample by a capillary electrophoresis method is provided that allows the apparatus to be reduced in size, allows a high analytical precision to be obtained, and can be carried out easily. The analytical process of the present invention is a process for analyzing a sample by a capillary electrophoresis method. The analytical process includes preparing a capillary tube to be used for the capillary electrophoresis method, and performing electrophoretic separation of a complex of a sample and an anionic group-containing compound that are bonded together, in the capillary tube, wherein the capillary tube includes an anionic layer that is formed of the anionic group-containing compound and that is coated on the inner wall of the capillary tube, and the anionic layer is fixed to the inner wall of the capillary tube by a covalent bond.Type: GrantFiled: August 29, 2007Date of Patent: March 20, 2012Assignees: National Institute of Advanced Industrial Science and Technology, Arkray, Inc.Inventors: Yoshihide Tanaka, Shinichi Wakida, Yusuke Nakayama, Satoshi Yonehara
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Publication number: 20120048734Abstract: An analysis apparatus is provided with a storage tank, an injection nozzle, a syringe, a collection nozzle, a test sample tank, a microchip having two or more separation channels, detectors, a waste liquid tank, a controller, and a power supply. The collection nozzle collects a specimen which becomes a test sample from a test sample container housing the specimen, and transfers the specimen to the test sample tank. The separation channels separate characteristic components contained in the test sample. The injection nozzle is distanced from the collection nozzle and injects the test sample from the test sample tank into the separation channels. The detectors detect the separated characteristic components in the separation channels.Type: ApplicationFiled: August 25, 2011Publication date: March 1, 2012Applicant: ARKRAY, Inc.Inventors: Koji Sugiyama, Daisuke Matsumoto, Yasunori Shiraki, Satoshi Yonehara
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Publication number: 20120012462Abstract: An electrophoresis chip that enables an apparatus to be small, analysis time to be short and glycosylated hemoglobin to be analyzed highly accurately is provided. The electrophoresis chip includes an upper substrate 4, a lower substrate 1, a first introduction reservoir 2a, a first recovery reservoir 2b and a capillary channel for sample analysis 3x; the first introduction reservoir 2a and the first recovery reservoir 2b are formed in the lower substrate 1; and the first introduction reservoir 2a and the first recovery reservoir 2b are in communication with each other via the capillary channel for sample analysis 3x.Type: ApplicationFiled: August 31, 2011Publication date: January 19, 2012Inventors: Koji Sugiyama, Satoshi Yonehara, Yusuke Nakayama
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Patent number: 8026078Abstract: The present invention provides a method of measuring a glycated protein in a sample using a redox reaction, by which the glycated protein can be measured accurately with high sensitivity. In order to remove a glycated amino acid present in the sample other than the glycated protein, the glycated amino acid is degraded in advance by causing a fructosyl amino acid oxidase to act thereon, and thereafter, a fructosyl amino acid oxidase is caused to act on the glycated protein in the presence of a tetrazolium compound and sodium azide to cause a redox reaction. The amount of the glycated protein is determined by measuring the redox reaction. As the glycated protein, glycated hemoglobin is preferable.Type: GrantFiled: January 29, 2003Date of Patent: September 27, 2011Assignee: ARKRAY Inc.Inventors: Satoshi Yonehara, Kaori Ishimaru, Tsuguki Komori
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Patent number: 8021855Abstract: A method of assaying a glycated protein in a sample with the use of redox reaction, in which highly reliable measurement can be obtained. A sample containing a glycated protein is treated with protease in the presence of a sulfonic acid compound, so that the glycated protein is degraded. The glycated portion of the resultant glycated protein degradation product is reacted with fructosyl amino acid oxidase, and this redox reaction is measured, thereby determining the amount of glycated protein. Sodium lauryl sulfate can be used as the sulfonic acid compound.Type: GrantFiled: April 28, 2003Date of Patent: September 20, 2011Assignee: ARKRAY Inc.Inventors: Satoshi Yonehara, Kaori Ishimaru, Kaoru Hirai
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Patent number: 8008085Abstract: A method of measuring HbA1c is provided that, even with a whole blood sample after storage, measurement accuracy substantially equal to a whole blood sample right after collection can be maintained. Whole blood is stored in a presence of a glycolytic inhibitor and protease is added to the stored whole blood sample to cleave hemoglobin in the whole blood sample. Then a glycated part of a hemoglobin fragment thereby obtained is treated with fructosyl amine oxidase. Thereafter, a glycation degree of HbA1c is determined by measuring a redox reaction between the glycated part and the fructosyl amine oxidase. Further, instead of storage of the whole blood in a presence of the glycolytic inhibitor, a strong electrolyte substance such as KCl, K2SO4, KNO, NaCl, Na2SO4, NaNO, MgCl2, MgSO4, Mg(NO)2, etc. is added to the whole blood after storage and a protease treatment is performed in a presence of the strong electrolyte substance.Type: GrantFiled: January 30, 2008Date of Patent: August 30, 2011Assignee: ARKRAY, Inc.Inventors: Satoshi Yonehara, Norio Inamura
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Publication number: 20110174621Abstract: A sample analysis method with improved separation accuracy is provided. The method relates to a method for analyzing a sample by electrophoresis using an electrophoresis apparatus provided with a channel and a sample reservoir formed in the channel. The method includes: placing the sample in the sample reservoir of the electrophoresis apparatus with the channel being filled with an electrophoresis running buffer; and performing electrophoresis by applying a voltage to both ends of the channel. The concentration of at least one of a) and b) is set to be approximately the same between the sample and the electrophoresis running buffer; wherein a) and b) are defined as follows: a) an ion that moves in the same direction as an analyte in the sample by the electrophoresis and has a smaller degree of mobility than the analyte, and b) an ion that moves in the opposite direction to the analyte.Type: ApplicationFiled: January 13, 2011Publication date: July 21, 2011Inventors: Satoshi Yonehara, Yusuke Nakayama
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Publication number: 20110155573Abstract: A method for analyzing hemoglobin by electrophoresis, capable of analyzing hemoglobin A1c (HbA1c) and modified hemoglobin with improved accuracy in a shortened analysis time is provided. The method for analyzing hemoglobin by electrophoresis includes performing electrophoresis under conditions in which an acidic substance having two or more carboxyl groups is present in an electrophoresis solution. At least two of the carboxyl groups of the acidic substance each have an acid dissociation constant (pKa) lower than the pH of the electrophoresis solution at the time of analysis.Type: ApplicationFiled: December 23, 2010Publication date: June 30, 2011Applicant: ARKRAY, Inc.Inventors: Yusuke Nakayama, Satoshi Yonehara
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Publication number: 20110015391Abstract: The present invention provides a stabilizer that can stabilize a salt of 10-(carboxymethylaminocarbonyn-3,7-bis(dimethylamino)phenothiazine or a derivative thereof even under the existence of moisture or under light irradiation. A compound described in at least one of (1) and (2) below is used as the stabilizer of the salt of 10-(carboxymethylaminocarbonyl)-3,7-bis(dimethylamino)phenothiazine or the derivative thereof.Type: ApplicationFiled: March 18, 2009Publication date: January 20, 2011Applicant: ARKRAY, INC.Inventors: Satoshi Yonehara, Norio Inamura
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Patent number: 7871789Abstract: An albumin denaturing agent for digesting an albumin by a protease efficiently is provided. The albumin denaturing agent contains quaternary ammonium having a hydrocarbon group with a carbon number of 12 or more, or a salt of the quaternary ammonium. The albumin in a sample is digested by the protease in the presence of the albumin denaturing agent, a glycated part of the thus obtained albumin digestion product and a FAOD effect a reaction, and a redox reaction between the glycated part and the FAOD is measured, thereby determining a ratio (GA (%)) of the glycated albumin of the glycated albumin with respect to the albumin.Type: GrantFiled: October 27, 2006Date of Patent: January 18, 2011Assignee: ARKRAY, Inc.Inventors: Satoshi Yonehara, Norio Imamura
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Patent number: RE43795Abstract: The present invention provides a method of pretreating a sample containing a glycated amine as an analyte, thereby enabling highly reliable measurement of a glycated amine. A glycated amino acid in the sample is degraded by causing a fructosyl amino acid oxidase (FAOD) to act thereon, and thereafter, a FAOD further is caused to act on the glycated amine as the analyte in the sample to cause a redox reaction. The amount of the glycated amine is determined by measuring the redox reaction. The substrate specificity of the FAOD caused to act on the glycated amino acid may be either the same as or different from that of the FAOD caused to act on the glycated amine. When using the same FAOD, a FAOD is caused to act on the glycated amino acid to degrade it, and thereafter, the sample is treated with a protease to inactivate the FAOD and also to degrade the glycated amine.Type: GrantFiled: October 9, 2002Date of Patent: November 6, 2012Assignee: ARKRAY, Inc.Inventors: Satoshi Yonehara, Tsuguki Komori