Patents by Inventor Satyawan Singh
Satyawan Singh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7959954Abstract: A bioactive fraction obtained from Xylocarpus that is useful for the treatment of diabetes and dyslipidemia. This fraction can be provided in a pharmaceutical composition that is useful as antidiabetic and antidyslipidemic agent, or can be used in a method of treating diabetes and dyslipidemia in a subject. Also, a process for the preparation of bioactive fraction from Xylocarpus. Isomeric xyloccensins and the preparation of such compounds. Also, pharmaceutical compositions comprising a therapeutically effective amount of such isomeric xyloccensins optionally along with one or more pharmaceutically acceptable carriers, additives, lubricant and diluents and the use of such pharmaceutical compositions in a method for treating dyslipidemia.Type: GrantFiled: September 11, 2006Date of Patent: June 14, 2011Assignee: Council of Scientific and Industrial ResearchInventors: Vijai Lakshmi, Ajet Saxena, Rajesh Kumar, Raghwendra Pal, Satyawan Singh, Arvind Kumar Srivastava, Preeti Tiwari, Deepak Raina, Anil Kumar Rastogi, Mahendra Nath Srivastava, Ramesh Chandra, Anju Puri, Ram Raghubir, Poonam Gupta, Narender Tadigoppula, Brijendra Kumar Tripathi, Sudhir Srivastava
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Publication number: 20110077294Abstract: The present invention provides an optically active compound of general formula (I) and salts thereof: wherein R? is selected from a group consisting of t-butyl amine, n-butylamine, iso-butylamine, iso-propyl amine, 4-phenyl-piperazine-1-ylamine, 4-(2-methoxyphenyl)-piperazin-1-ylamine, and 3,4-dimethoxy phenethyl amine; wherein R1, R2 and R3 are selected from the group consisting of hydrogen, methyl or iso pentenyl; R4, R5 and R6 are selected from the group consisting of Oil, O-alkyl, O-benzyl, O-substituted phenyl or combination thereof.Type: ApplicationFiled: August 2, 2007Publication date: March 31, 2011Inventors: Ram Pratap, Himanshu Singh, Alok Kumar Verma, Amar Bahadur Singh, Priti Priti Tiwari Tiwari, Mukesh Srivastava, Arvind Kumar Srivastava, Anil Kumar Dwivedi, Satyawan Singh, Pratima Pnahma Svivastva Srivastava, Shio Kumar Singh, Chandishwar Nath, Ram Raghubir
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Publication number: 20100093870Abstract: The present invention relates to A composition obtained from the lipid soluble extract of rhizomes and leaves of Curcuma species of Zingiberaceae family, useful for the treatment of neurocerebrovascular disorders, said composition comprising fraction A consisting of ar-turmerone of formula 1, and turmerone of formula 2, and/or along with fraction B consisting of curcumene and zingiberine, and/or fraction C consisting of germacrone, curcumerone, zedoarone, sedoarondiol, isozdedoaronidiol, curcumenone, and curlone, and/or pharmaceutically acceptable additives and a method of treating neurocerebrovascular disorders in animals including humans using said composition by administering therapeutically effective amount of lipid soluble extract.Type: ApplicationFiled: May 18, 2009Publication date: April 15, 2010Inventors: Madhur Ray, Raghwendra Pal, Satyawan Singh, Nandoo Mal Khanna
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Patent number: 7404962Abstract: A combination kit for the treatment of malaria caused by Plasmodium vivax (P. vivax) having individual doses of an anti-malarial agent, 3-[1-[[4-[(6-methoxy-8-quinolinyl)amino]pentyl]amino]ethylidene]-dihydro-2(3H)-furanone (I) in the form of capsules; individual doses of the anti-malarial agent, chloroquine in the form of tablets; and instruction material for the administration of the two anti-malarial drugs. The combination kit is particularly suited for a 6 days treatment regimen where the treatment is rendered by five tablets containing 500 mg of chloroquine phosphate (equivalent to 300 mg base), three to be taken on day one and one each on days two and three; and five capsules containing 25 mg of 3-[1-[[4-[(6-methoxy-8-quinolinyl)amino]pentyl]amino]ethylidene]-dihydro-2(3H)-furanone (I), one each to be taken on days two to six.Type: GrantFiled: August 30, 2000Date of Patent: July 29, 2008Assignees: Nicholas Piramal India Limited, Council of Scientific and Industrial ResearchInventors: Francis Joseph Pinto, Swati Ajay Piramal, Ram Pratap, Amiya Prasad Bhaduri, Harsh Pati Thapliyal, Sunil Kumar Puri, Guru Prasad Dutta, Anil Kumar Dwivedi, Satyawan Singh, Pratima Srivastava, Vikash Chandra Pandey, Sudhir Srivastava, Shio Kumar Singh, Ram Chandra Gupta, Jagdishwar Sahai Srivastava, Omkar Prasad Asthana
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Patent number: 7365218Abstract: The present invention provides an improved process for the preparation of Guggulsterones which comprises epoxidising 16-dihydropegnenolone acetate (16 DPA) by reacting 16DPA with hydrogen peroxide reagent adduct in the presence of a co-base in a polar solvent to obtain 3 ? hydroxy-16 ?, 17-oxido-5 pregnen-20-one, converting the 3 ? hydroxy-16?, 17-oxido-5-pregnen-20-one by reacting with hydrazine in the presence of a strong base at refluxing temperature followed by oxidation to obtain desired guggulsterones viz. to 5, 17-(20)-cis and trans pregnadiene-3 ?, 16-diol of the formula Ia and Ib.Type: GrantFiled: March 20, 2003Date of Patent: April 29, 2008Assignee: Council of Scientific and Industrial ResearchInventors: Ram Pratap, Dharmendra Pratap Singh, Raghavendra Pal, Satyawan Singh
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Publication number: 20070178179Abstract: A bioactive fraction obtained from Xylocarpus that is useful for the treatment of diabetes and dyslipidemia. This fraction can be provided in a pharmaceutical composition that is useful as antidiabetic and antidyslipidemic agent, or can be used in a method of treating diabetes and dyslipidemia in a subject. Also, a process for the preparation of bioactive fraction from Xylocarpus. Novel isomeric xyloccensins and the preparation of such compounds. Also, pharmaceutical compositions comprising a therapeutically effective amount of such novel isomeric xyloccensins optionally along with one or more pharmaceutically acceptable carriers, additives, lubricant and diluents and the use of such pharmaceutical compositions in a method for treating dyslipidemia.Type: ApplicationFiled: September 11, 2006Publication date: August 2, 2007Inventors: Vijai Lakshmi, Ajet Saxena, Rajesh Kumar, Raghwendra Pal, Satyawan Singh, Arvind Srivastava, Preeti Tiwari, Deepak Raina, Anil Rastogi, Mahendra Srivastava, Ramesh Chandra, Anju Puri, Ram Raghubir, Poonam Gupta, Narender Tadigoppula, Brijendra Tripathi, Sudhir Srivastava
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Patent number: 7183291Abstract: The present invention a novel use of primaquine derivative N1-(3-ethylidinotetrahydrofuran-2-one)-N4-(6-methoxy-8-quinolinyl)-1,4-pentanediamine in the treatment and controlling the spread of malaria. In particular, the present invention discloses a method of treatment of malaria by the use of primaquine derivative N1-(3-ethylidinotetrahydrofuran-2-one)-N4-(6-methoxy-8-quinolinyl)-1,4-pentanediamine as a gametocytocidal agent.Type: GrantFiled: May 21, 1999Date of Patent: February 27, 2007Assignee: Council of Scientific and Industrial ResearchInventors: Ram Pratap, Amiya Prasad Bhaduri, Harsh Pati Thapliyal, Sunil Kumar Puri, Guru Prasad Dutta, Anil Kumar Dwivedi, Satyawan Singh, Pratima Srivastava, Vikash Chandra Pandey, Sudhir Srivastava, Shio Kumar Singh, Ram Chandra Gupta, Jagdishwar Sahai Srivastava, Omkar Prasad Asthana
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Publication number: 20060160989Abstract: This present invention relates to new peptides L-N-substituted-alanyl-N-substituted-glycyl-N-substituted-glycyl-L-aspartyl-N-substituted-glycyl-L-lysyl (SEQ ID NO: 1, where R1—R4 of formula 1 are H and R5 of formula 1 is OH) derivatives which can be used as therapeutic agents for allergy/asthma and a process for preparing the said compounds and its formulation for administration by nasal route.Type: ApplicationFiled: December 22, 2003Publication date: July 20, 2006Applicant: COUNCIL OF SCIENTIC AND INDUSTRIAL RESEARCHInventors: Bijoy Kundu, Kamlesh Agarwal, Sanjay Khare, Rashmi Singh, Amar Nath, Anil Dwivedi, Satyawan Singh, Prem Gupta
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Publication number: 20060141024Abstract: The present invention relates to a method for preparation of synergistic combination kits of ?,?-arteether, sulfadoxin and pyrimethamine for the treatment of severe/multi-drug resistant cerebral malaria.Type: ApplicationFiled: December 28, 2004Publication date: June 29, 2006Applicant: COUNCIL OF SIENTIFIC AND INDUSTRIAL RESEARCHInventors: Renu Tripathi, Sunil Puri, Jagdishwar Srivastava, Satyawan Singh, Omkar Asthana, Anil Dwivedi
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Publication number: 20060051438Abstract: The present invention relates to A composition obtained from the lipid soluble extract of rhizomes and leaves of Curcuma species of Zingiberaceae family, useful for the treatment of neurocerebrovascular disorders, said composition comprising fraction A consisting of ar-turmerone of formula 1, and turmerone of formula 2, and/or along with fraction B consisting of curcumene and zingiberine, and/or fraction C consisting of germacrone, curcumerone, zedoarone, sedoarondiol, isozdedoaronidiol, curcumenone, and curlone, and/or pharmaceutically acceptable additives and a method of treating neurocerebrovascular disorders in animals including humans using said composition by administering therapeutically effective amount of lipid soluble extract.Type: ApplicationFiled: August 24, 2005Publication date: March 9, 2006Inventors: Madhur Ray, Raghwendra Pal, Satyawan Singh, Nandoo Khanna
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Patent number: 6991814Abstract: The present invention relates to A composition obtained from the lipid soluble extract of rhizomes and leaves of Curcuma species of Zingiberaceae family, useful for the treatment of neurocerebrovascular disorders, said composition comprising fraction A consisting of ar-turmerone of formula 1, and turmerone of formula 2, and/or along with fraction B consisting of curcumene and zingiberine, and/or fraction C consisting of germacrone, curcumerone, zedoarone, sedoarondiol, isozdedoaronidiol, curcumenone, and curlone, and/or pharmaceutically acceptable additives and a method of treating neurocerebrovascular disorders in animals including humans using said composition by administering therapeutically effective amount of lipid soluble extract.Type: GrantFiled: December 13, 2002Date of Patent: January 31, 2006Assignee: Council of Scientific and Industrial ResearchInventors: Madhur Ray, Raghwendra Pal, Satyawan Singh, Nandoo Mal Khanna
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Patent number: 6896901Abstract: The present invention provides new uses of Gugulipid, an ethyl acetate extract of the resin of the plant Comiphora wighitii, for controlling or preventing cognitive dysfunction, hyperglycemia and some infective conditions of the skin and a method of preparing Gugulipid by agitating the resin in shake flask assembly or sonicating assembly and preparing a solid or a creamy dosage forms.Type: GrantFiled: December 22, 2000Date of Patent: May 24, 2005Assignee: Council of Scientific & Industrial ResearchInventors: Ram Pratap, Raghwendra Pal, Satyawan Singh, Girja Shankar, Chandeshwar Nath, Hemant Kumar Singh, Depak Raina, Arwind Kumar Srivastava, Anil Kumar Rastogi, Puvvada Sri Ramachandra Murthy, Sudhir Srivastava, Onkar Prasad Asthana, Narenda Singh, Nitya Nand
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Publication number: 20040186306Abstract: The present invention provides an improved process for the preparation of Guggulsterones which comprises epoxidising 16-dihydropegnenolone acetate (16 DPA) by reacting 16DPA with hydrogen peroxide reagent adduct in the presence of a co-base in a polar solvent to obtain 3 &bgr; hydroxy-16 &agr;, 17-oxido-5 pregnen-20-one, converting the 3 &bgr; hydroxy-16&agr;, 17-oxido-5-pregnen-20-one by reacting with hydrazine in the presence of a strong base at refluxing temperature followed by oxidation to obtain desired guggulsterones viz. to 5, 17-(20)-cis and trans pregnadiene-3 &bgr;, 16-diol of the formula Ia and Ib.Type: ApplicationFiled: March 20, 2003Publication date: September 23, 2004Applicant: COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCHInventors: Ram Pratap, Dharmendra Pratap Singh, Raghavendra Pal, Satyawan Singh
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Patent number: 6740639Abstract: The invention provides novel inclusion complexes of highly potent opioid peptide of L-Tyrosyl-D-alanyl-glycyl-N-methylphenylalanyl-glycyl-isopropylamide with cyclodextrin, pharmaceutical preparations containing these inclusion complexes of L-Tyrosyl-D-alanyl-glycyl-N-methylphenylalanyl-glycyl-isopropylamide with cyclodextrin derivatives, the complexes being better soluble in water and having improved biopharmaceutical properties such as lesser toxicity, better analgesic action and non-addiction properties.Type: GrantFiled: March 29, 2000Date of Patent: May 25, 2004Assignee: Council of Scientific & Industrial ResearchInventors: Anil Kumar Dwivedi, Madhu Khanna, Wahajul Haq, Ram Raghubir, Sudhir Srivastava, Puvvada Sri Ramchandra Murthy, Onkar Prasad Asthana, Jagdishwar Sahay Srivastava, Satyawan Singh
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Publication number: 20040033277Abstract: The present invention relates to A composition obtained from the lipid soluble extract of rhizomes and leaves of Curcuma species of Zingiberaceae family, useful for the treatment of neurocerebrovascular disorders, said composition comprising fraction A consisting of ar-turmerone of formula 1, and turmerone of formula 2, and/or along with fraction B consisting of curcumene and zingiberine, and/or fraction C consisting of germacrone, curcumerone, zedoarone, sedoarondiol, isozdedoaronidiol, curcumenone, and curlone, and/or pharmaceutically acceptable additives and a method of treating neurocerebrovascular disorders in animals including humans using said composition by administering therapeutically effective amount of lipid soluble extract.Type: ApplicationFiled: December 13, 2002Publication date: February 19, 2004Applicant: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCHInventors: Madhur Ray, Raghwendre Pal, Satyawan Singh, Nandoo Man Khanna
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Publication number: 20030199697Abstract: The present invention a novel use of primaquine derivative N1-(3-ethylidinotetrahydrofuran-2-one)-N4-(6-methoxy-8-quinolinyl)-1,4-pentanediamine in the treatment and contolling the spread of malaria. In particular, the present invention discloses a method of treatment of malaria by the use of primaquine derivative N1-(3-ethylidinotetrahydrofuran-2-one)-N4-(6-methoxy-8-quinolinyl)-1,4-pentanediamine as a gametocytocidal agent.Type: ApplicationFiled: May 21, 1999Publication date: October 23, 2003Inventors: RAM PRATAP, AMIYA PRASAD BHADURI, HARSH PATI THAPLIYAL, SUNIL KUMAR PURI, GURU PRASAD DUTTA, ANIL KUMAR DWIVEDI, SATYAWAN SINGH, PRATIMA SRIVASTAVA, VIKASH CHANDRA PANDEY, SUDHIR SRIVASTAVA, SHIO KUMAR SINGH, RAM CHANDRA GUPTA, JAGDISHWAR SAHAI SRIVASTAVA, OMKAR PRASAD ASTHANA
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Publication number: 20030099729Abstract: The present invention provides new uses of Gugulipid, an ethyl acetate extract of the resin of the plant Comiphora wighitii, for controlling or preventing cognitive dysfunction, hyperglycemia and some infective conditions of the skin and a method of preparing Gugulipid by agitating the resin in shake flask assembly or sonicating assembly and preparing a solid or a creamy dosage forms.Type: ApplicationFiled: December 20, 2002Publication date: May 29, 2003Inventors: Ram Pratap, Raghwendra Pal, Satyawan Singh, Girja Shankar, Chandeshwar Nath, Hemant Kumar Singh, Depak Raina, Arwind Kumar Srivastava, Anil Kumar Rastogi, Puvvada Sri Ramachandra Murthy, Sudhir Srivastava, Onkar Prasad Asthana, Narendra Singh, Nitya Nand
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Publication number: 20020119206Abstract: The present invention provides new uses of Gugulipid, an ethyl acetate extract of the resin of the plant Comiphora wighitii, for controlling or preventing cognitive dysfunction, hyperglycemia and some infective conditions of the skin and a method of preparing Gugulipid by agitating the resin in shake flask assembly or sonicating assembly and preparing a solid or a creamy dosage forms.Type: ApplicationFiled: December 22, 2000Publication date: August 29, 2002Inventors: Ram Pratap, Raghwendra Pal, Satyawan Singh, Girja Shankar, Chandeshwar Nath, Hemant Kumar Singh, Depak Raina, Arwind Kumar Srivastava, Anil Kumar Rastogi, Puvvada Ramachandra Murthy, Sudhir Srivastava, Onkar Prasad Asthana, Narendra Singh, Nitya Nand
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Patent number: 6326023Abstract: The present invention relates to a synergistic formulation comprising pharmaceutically effective amount of &agr;/&bgr; arteether and a neutralized refined vegetable oil suitable for administration by rectal route, method for the treatment of cerebral and comatose malaria and process for the preparation of the said formulation.Type: GrantFiled: March 28, 2000Date of Patent: December 4, 2001Assignee: Council of Scientific & Industrial ResearchInventors: Guru Prakash Dutta, Dharam Chand Jain, Ranjendra Singh Bhakuni, Sudhanshu Saxena, Sangeeta Dhawan, Suman Preet Singh Khanuja, Sushil Kumar, Renu Tripathi, Aseem Umesh, Nuzhat Kamal, Anil Kumar Dwivedi, Satyawan Singh