Abstract: The present invention relates generally to particles that include one or more antimicrobial agents therein and/or thereon. The particles may be provided with one or more coatings that contain one or more antimicrobial agents, or the one or more antimicrobial agents may be embedded in the particles. The present invention also relates to goods such as medical devices, personal care products, and household devices that incorporate one or more antimicrobial particles. The goods may be provided with one or more coatings that contain the antimicrobial particles, or the antimicrobial particles may be physically embedded in the medical devices. The present invention is further directed towards methods of making such medical devices. The goods incorporating the antimicrobial particles may be used in accordance with methods of killing microorganisms and preventing infections.