Patents by Inventor Scott A. Uhland
Scott A. Uhland has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230210781Abstract: A drug delivery device includes an enteric capsule enclosing an internal volume and a plurality of drug containing particles positioned within the internal volume. Each of the plurality of drug containing particles includes a matrix body and an active pharmaceutical ingredient (API) distributed within the matrix body. The plurality of drug containing particles are configured to penetrate tissue, such as intestinal mucosa.Type: ApplicationFiled: June 10, 2021Publication date: July 6, 2023Inventors: Scott UHLAND, Mihee KIM, Manish MONGA, Samuel SPIGELMAN
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Publication number: 20230007883Abstract: Various exemplary methods, systems, and devices for injection pump needle mechanics are provided.Type: ApplicationFiled: November 16, 2020Publication date: January 12, 2023Inventors: Steven M. VESOLE, Brandon MCKENZIE, Scott UHLAND
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Patent number: 11547447Abstract: Devices, systems, and methods for delivering fluid are provided. Devices include a housing configured for intravaginal deployment and retention, at least one reservoir configured to contain a fluid, and a fluid dispensing mechanism configured to dispense the fluid past the cervix and to the uterus of the subject. Methods include intravaginally deploying and retaining a device in the subject, and dispensing the fluid from the device such that the fluid is driven past the cervix to the uterus of the subject.Type: GrantFiled: February 22, 2021Date of Patent: January 10, 2023Assignee: Palo Alto Research Center IncorporatedInventors: David Mathew Johnson, Scott A. Uhland, Robert Thomas Krivacic, Ramkumar Abhishek, Martin Sheridan
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Publication number: 20210169525Abstract: Devices, systems, and methods for delivering fluid are provided. Devices include a housing configured for intravaginal deployment and retention, at least one reservoir configured to contain a fluid, and a fluid dispensing mechanism configured to dispense the fluid past the cervix and to the uterus of the subject. Methods include intravaginally deploying and retaining a device in the subject, and dispensing the fluid from the device such that the fluid is driven past the cervix to the uterus of the subject.Type: ApplicationFiled: February 22, 2021Publication date: June 10, 2021Inventors: David Mathew Johnson, Scott A. Uhland, Ramukumar Abhishek, Robert Thomas Krivacic, Martin Sheridan
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Patent number: 10925644Abstract: Devices, systems, and methods for delivering fluid are provided. Devices include a housing configured for intravaginal deployment and retention, at least one reservoir configured to contain a fluid, and a fluid dispensing mechanism configured to dispense the fluid past the cervix and to the uterus of the subject. Methods include intravaginally deploying and retaining a device in the subject, and dispensing the fluid from the device such that the fluid is driven past the cervix to the uterus of the subject.Type: GrantFiled: October 9, 2017Date of Patent: February 23, 2021Assignee: Palo Alto Research Center IncorporatedInventors: David Mathew Johnson, Scott A. Uhland, Ramkumar Abhishek, Robert Thomas Krivacic, Martin Sheridan
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Patent number: 10806629Abstract: An apparatus includes a pad assembly, an injector assembly, an injector driver, and a fluid source. The pad assembly is sized and configured to be placed on a forehead of a patient. The injector assembly includes a body, a flexible cannula, and a needle. The body is configured to be removably secured to the pad assembly. The cannula is sized to be inserted through an incision in an eye of a patient. The needle is slidably disposed in the cannula. The injector driver is operable to drive the needle longitudinally relative to the flexible cannula. The fluid source assembly is in fluid communication with the needle.Type: GrantFiled: May 31, 2017Date of Patent: October 20, 2020Assignee: GYROSCOPE THERAPEUTICS LIMITEDInventors: Daniel W. Price, Brendan J. Oberkircher, James G. Lee, Clinton Denlinger, Daniel J. Prenger, Geoffrey King, Scott Uhland, Mark C. Tsai, Michael F. Keane, Isaac J. Khan, Benjamin L. Ko, Thomas E. Meyer, Denis P. Turner
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Patent number: 10806630Abstract: An apparatus includes a pad assembly, an injector assembly, an injector driver, and a fluid source. The pad assembly is sized and configured to be placed on a forehead of a patient. The injector assembly includes a body, a flexible cannula, and a needle. The body is configured to be removably secured to the pad assembly. The cannula is sized to be inserted through an incision in an eye of a patient. The needle is slidably disposed in the cannula. The injector driver is operable to drive the needle longitudinally relative to the flexible cannula. The fluid source assembly is in fluid communication with the needle.Type: GrantFiled: April 29, 2020Date of Patent: October 20, 2020Assignee: GYROSCOPE THERAPEUTICS LIMITEDInventors: Daniel W. Price, Brendan J. Oberkircher, James G. Lee, Clinton Denlinger, Daniel J. Prenger, Geoffrey King, Scott Uhland, Mark C. Tsai, Michael F. Keane, Isaac J. Khan, Benjamin L. Ko, Thomas E. Meyer, Denis P. Turner
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Publication number: 20200297531Abstract: An apparatus includes a pad assembly, an injector assembly, an injector driver, and a fluid source. The pad assembly is sized and configured to be placed on a forehead of a patient. The injector assembly includes a body, a flexible cannula, and a needle. The body is configured to be removably secured to the pad assembly. The cannula is sized to be inserted through an incision in an eye of a patient. The needle is slidably disposed in the cannula. The injector driver is operable to drive the needle longitudinally relative to the flexible cannula. The fluid source assembly is in fluid communication with the needle.Type: ApplicationFiled: April 29, 2020Publication date: September 24, 2020Inventors: Daniel W. Price, Brendan J. Oberkircher, James G. Lee, Clinton Denlinger, Daniel J. Prenger, Geoffrey King, Scott Uhland, Mark C. Tsai, Michael F. Keane, Isaac J. Khan, Benjamin L. Ko, Thomas E. Meyer, Denis P. Turner
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Patent number: 10632294Abstract: Devices and methods are provided for transmucosal drug delivery. The transmucosal drug delivery device may include a housing configured for intralumenal deployment, such as intravaginally, into a human or animal subject; a drug-dispensing portion which contains at least one drug, the drug-dispensing portion being configured to dispense the drug from the housing by positive displacement; and a permeability enhancer-dispensing portion configured to release or generate a permeability enhancing substance to disrupt at least one region of a mucosal barrier adjacent to the housing at a selected time while intralumenally deployed in the human or animal subject. The device may be operable to dispense the drug from the housing to a region of the mucosal barrier disrupted by the permeability enhancing substance.Type: GrantFiled: November 10, 2014Date of Patent: April 28, 2020Assignee: Palo Alto Research Center IncorporatedInventors: Scott Uhland, Eric Peeters, Hussain Fatakdawala
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Patent number: 10596358Abstract: Retention devices and methods are provided for drug delivery. The device may include a housing configured for intraluminal deployment into a human or animal subject and at least one reservoir contained within the housing. The at least one reservoir may have an actuation end and a release end and contain at least one drug formulation. A plug may be contained within the at least one reservoir and be moveable from the actuation end toward the release end. The device may also include an actuation system operably connected to the actuation end of the at least one reservoir and configured to drive the at least one drug formulation from the reservoir. The device may also include at least one retention member affixed to the housing and movable between a non-stressed position, a deployment position, and a retention position for retaining the device in an intraluminal location in the subject.Type: GrantFiled: July 24, 2017Date of Patent: March 24, 2020Assignee: PALO ALTO RESEARCH CENTER INCORPORATEDInventors: David Mathew Johnson, Martin Sheridan, Scott A. Uhland, Ramkumar Abhishek, Eric Peeters, Timothy J. Curley, Felicia Linn, Philipp H. Schmaelzle
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Patent number: 10278675Abstract: Devices, systems, and methods for detecting estrus in subjects are provided. Devices include a housing configured for intravaginal/intrauterine deployment and retention and a sensor disposed in or on the housing, and are configured to use condition information sensed by the sensor to determine an estrus condition of the subject. Methods include deploying a device in the subject, sensing the condition information, and determining an estrus condition using the condition information. Systems include a device configured to communicate with a base station and/or with other implanted devices, which are located within a reception radius thereof, regarding the determined estrus condition.Type: GrantFiled: July 31, 2014Date of Patent: May 7, 2019Assignee: PALO ALTO RESEARCH CENTER INCORPORATEDInventors: David Mathew Johnson, Scott A. Uhland, Ramkumar Abhishek, Robert Thomas Krivacic, Martin Sheridan
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Publication number: 20180338904Abstract: Devices and methods are provided for drug delivery. The device may include a housing configured for intralumenal deployment into a human or animal subject and a reservoir contained within the housing and having an actuation end and a release end. The release end may include at least one outlet. A first drug formulation and a second drug formulation may be disposed within the reservoir and adjacent to each other and immiscible, or separated from each other by a first barrier. The device may also include a plug within the reservoir at the actuation end, the plug being movable toward the release end to drive the first and second drug formulations out of the reservoir. The device may also include an actuation system operably connected to the actuation end of the reservoir and configured to drive the plug toward the release end and release the drug formulations from the reservoir.Type: ApplicationFiled: June 1, 2018Publication date: November 29, 2018Applicant: Inguran, LLCInventors: Scott A. Uhland, Ramkumar Abhishek, Eric Peeters, Timothy J. Curley
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Patent number: 10064995Abstract: Approaches for determining the delivery success of a particle, such as a drug particle, are disclosed. A system for monitoring delivery of particles to biological tissue includes a volume, an optical component, a detector, and an analyzer. The volume comprises a space through which a particle can pass in a desired direction. The optical component is configured to provide a measurement light. The detector is positioned to detect light emanating from the particle in response to the measurement light. The detected light is modulated as the particle moves along a detection axis. The detector is configured to generate a time-varying signal in response to the detected light. The analyzer is configured to receive the time-varying signal and determine a delivery success of the particle into a biological tissue based upon characteristics of the time-varying signal.Type: GrantFiled: July 13, 2016Date of Patent: September 4, 2018Assignee: Palo Alto Research Center IncorporatedInventors: Peter Kiesel, Joerg Martini, Eugene M. Chow, Scott Uhland, Noble M. Johnson
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Patent number: 9999720Abstract: Devices and methods are provided for drug delivery. The device may include a housing having a first compartment containing a drug in a dry, solid form, a second compartment containing a liquid carrier for the drug, and an expansion member located within or adjacent to the first or second compartment. The second compartment may be fluidly connectable to the first compartment by a rupturable barrier or mechanical valve. The device may also include an actuation system configured to expand the expansion member to rupture the rupturable barrier or open the mechanical valve and permit the liquid carrier to flow into the first compartment and mix with the drug to form a reconstituted drug solution.Type: GrantFiled: September 27, 2012Date of Patent: June 19, 2018Assignee: PALO ALTO RESEARCH CENTER INCORPORATEDInventors: Scott A. Uhland, Felicia Linn, Michael I. Recht
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Publication number: 20180028228Abstract: Devices, systems, and methods for delivering fluid are provided. Devices include a housing configured for intravaginal deployment and retention, at least one reservoir configured to contain a fluid, and a fluid dispensing mechanism configured to dispense the fluid past the cervix and to the uterus of the subject. Methods include intravaginally deploying and retaining a device in the subject, and dispensing the fluid from the device such that the fluid is driven past the cervix to the uterus of the subject.Type: ApplicationFiled: October 9, 2017Publication date: February 1, 2018Inventors: David Mathew Johnson, Scott A. Uhland, Ramkumar Abhishek, Robert Thomas Krivacic, Martin Sheridan
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Publication number: 20170360606Abstract: An apparatus includes a pad assembly, an injector assembly, an injector driver, and a fluid source. The pad assembly is sized and configured to be placed on a forehead of a patient. The injector assembly includes a body, a flexible cannula, and a needle. The body is configured to be removably secured to the pad assembly. The cannula is sized to be inserted through an incision in an eye of a patient. The needle is slidably disposed in the cannula. The injector driver is operable to drive the needle longitudinally relative to the flexible cannula. The fluid source assembly is in fluid communication with the needle.Type: ApplicationFiled: May 31, 2017Publication date: December 21, 2017Inventors: Daniel W. Price, Brendan J. Oberkircher, James G. Lee, Clinton Denlinger, Daniel J. Prenger, Geoffrey King, Scott Uhland, Mark C. Tsai, Michael F. Keane, Isaac J. Khan, Benjamin L. Ko, Thomas E. Meyer, Denis P. Turner
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Publication number: 20170319834Abstract: Retention devices and methods are provided for drug delivery. The device may include a housing configured for intraluminal deployment into a human or animal subject and at least one reservoir contained within the housing. The at least one reservoir may have an actuation end and a release end and contain at least one drug formulation. A plug may be contained within the at least one reservoir and be moveable from the actuation end toward the release end. The device may also include an actuation system operably connected to the actuation end of the at least one reservoir and configured to drive the at least one drug formulation from the reservoir. The device may also include at least one retention member affixed to the housing and movable between a non-stressed position, a deployment position, and a retention position for retaining the device in an intraluminal location in the subject.Type: ApplicationFiled: July 24, 2017Publication date: November 9, 2017Inventors: David Mathew Johnson, Martin Sheridan, Scott A. Uhland, Ramkumar Abhishek, Eric Peeters, Timothy J. Curley, Felicia Linn, Philipp H. Schmaelzle
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Patent number: 9801660Abstract: Devices, systems, and methods for delivering fluid are provided. Devices include a housing configured for intravaginal deployment and retention, at least one reservoir configured to contain a fluid, and a fluid dispensing mechanism configured to dispense the fluid past the cervix and to the uterus of the subject. Methods include intravaginally deploying and retaining a device in the subject, and dispensing the fluid from the device such that the fluid is driven past the cervix to the uterus of the subject.Type: GrantFiled: July 31, 2014Date of Patent: October 31, 2017Assignee: Palo Alto Research Center IncorporatedInventors: David Mathew Johnson, Scott A. Uhland, Ramkumar Abhishek, Robert Thomas Krivacic, Martin Sheridan
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Patent number: 9744341Abstract: Retention devices and methods are provided for drug delivery. The device may include a housing configured for intraluminal deployment into a human or animal subject and at least one reservoir contained within the housing. The at least one reservoir may have an actuation end and a release end and contain at least one drug formulation. A plug may be contained within the at least one reservoir and be moveable from the actuation end toward the release end. The device may also include an actuation system operably connected to the actuation end of the at least one reservoir and configured to drive the at least one drug formulation from the reservoir. The device may also include at least one retention member affixed to the housing and movable between a non-stressed position, a deployment position, and a retention position for retaining the device in an intraluminal location in the subject.Type: GrantFiled: January 15, 2013Date of Patent: August 29, 2017Assignee: Palo Alto Research Center IncorporatedInventors: David Mathew Johnson, Martin Sheridan, Scott A. Uhland, Ramkumar Abhishek, Eric Peeters, Timothy J. Curley, Felicia Linn, Philipp H. Schmaelzle
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Patent number: 9717526Abstract: Devices and methods are provided for drug delivery. The device may include a housing configured for intraluminal deployment into a human or animal subject and first and second reservoirs within the housing, each reservoir having an actuation end, an opposed release end, and a plug moveable from the actuation end toward the release end. First and second drug formulations may be contained in the first and second reservoirs, respectively. The device may also include one or more actuation systems configured to drive the first and second plugs so as to drive the first and second drug formulations from the first and second reservoirs. The housing may include a porous membrane sidewall in fluid communication with the release ends of the first and second reservoirs, the porous membrane sidewall being configured to distribute the first and second drug formulations driven from the first and second reservoirs.Type: GrantFiled: December 19, 2014Date of Patent: August 1, 2017Assignee: Palo Alto Research Center IncorporatedInventors: Scott A. Uhland, Ramkumar Abhishek, Eric Peeters, Timothy J. Curley, Felicia Linn