Abstract: Robotic systems for orthopedic surgery are provided. The robotic systems may include at least first and second motors coupled to each other. An output shaft of one of the motors may be connectable to a surgical tool guide. An output shaft of another of the motors may be coupled to a portion of a ball and socket joint. A corresponding portion of the ball and socket joint may be coupled to a bone mount which may be attached to a bone to mount the first and second motors to bone for performing orthopedic surgical procedures.

Abstract: Immune cells engineered to reduce or eliminate expression and/or the function of a NR4A, TOX, NR4A and a TOX or NR4A and a TOX with increasing expression of IL-21 in said cells are disclosed. Also cells engineered to inhibit expression and/or function of NFAT/AP-1 pathway are provided. Disclosed cells are T and NK cells. It can be expanded to create homogeneous or heterogenous cell populations and/or combined with pharmaceutically acceptable carriers. It can be CAR cells. Methods to induce an immune response and treat conditions requiring selective immunotherapy, comprising contacting a target cell with the cells or compositions as described herein. The contacting can be performed in vitro or in vivo, thereby providing immunotherapy to a subject. Additionally presented herein are methods of producing such engineered cells. Kits containing the materials for making and using the cells are also provided.

Abstract: A fishing pole holder mount for mounting to a watercraft or other structure that is capable of holding more than one fishing pole at the same time, wherein the fishing pole holders are horizontally and vertically repositionable relative to one another and the base of the fishing pole holder mount. The fishing pole holder mount of the present invention also allows a user to specify the number of fishing pole holders removably attached thereto.

Abstract: A fishing pole holder mount for mounting to a watercraft or other structure that is capable of holding more than one fishing pole at the same time, wherein the fishing pole holders are horizontally and vertically repositionable relative to one another and the base of the fishing pole holder mount. The fishing pole holder mount of the present invention also allows a user to specify the number of fishing pole holders removably attached thereto.