Abstract: The present invention relates to a process and apparatus for quantifying solid residue on a sample. The process includes using a solid substrate and an aerosolizing device, adding a solid material to the aerosolizing device, forming a particle cloud of solid particles, wherein at least 1% of the mass concentration of solid particles have a mass median aerodynamic particle diameter up to about 10 ?m, thus applying the solid particles to the solid substrate(s) to form treated substrate(s), maintaining at a temperature of from about 30 to about 120° C. for at least a portion of the process, and removing a portion of solid particles from the treated substrate(s), and analyzing said at least one sample. The present invention further comprises an apparatus for applying solid particles to a substrate. The process can be used, for example, to analyze the dirt pickup resistance of a solid sample.

Abstract: Among other things, there are disclosed embodiments of an intramedullary nail system for use in pediatric cases, including an intramedullary nail and a targeting assembly. Embodiments of the nail may be one-piece and include a proximal portion, a medial portion and a distal portion. The junction of the medial portion and distal portion is a bend that provides a small angle between the medial portion and the distal portion as viewed when the nail is substantially in a medial-lateral plane. The targeting assembly attaches to the proximal portion of the nail securely and enables easy insertion of fixing screws.

Abstract: There are disclosed embodiments of screws for use in orthopedic surgery, particularly in pediatric patients. In some embodiments, inner and outer implantable members are provided, with the outer implantable member threadable on the inner implantable member to provide compression on two or more bone parts. In some embodiments, screw members are provided with a threaded shaft, and the thread continues into the head of the screw member to enable the thread to remain in pediatric bone.

Abstract: Described herein are composites that are relatively lightweight, high strength and low thermal conductivity. Also described herein are methods for the manufacture and use thereof.

Abstract: There are disclosed embodiments of screws for use in orthopedic surgery, particularly in pediatric patients. In some embodiments, inner and outer implantable members are provided, with the outer implantable member threadable on the inner implantable member to provide compression on two or more bone parts. In some embodiments, screw members are provided with a threaded shaft, and the thread continues into the head of the screw member to enable the thread to remain in pediatric bone.

Abstract: There are disclosed embodiments of screws for use in orthopedic surgery, particularly in pediatric patients. In some embodiments, inner and outer implantable members are provided, with the outer implantable member threadable on the inner implantable member to provide compression on two or more bone parts. In some embodiments, screw members are provided with a threaded shaft, and the thread continues into the head of the screw member to enable the thread to remain in pediatric bone.

Abstract: Various embodiments provide drug products and dry powder inhalers. With various embodiments of the present invention, a de-agglomeration chamber and by-pass channel are provided which allow for various de-agglomerating capabilities for dry powder dispensers.

Abstract: Among other things, there are disclosed embodiments of an intramedullary nail system for use in pediatric cases, including an intramedullary nail and a targeting assembly. Embodiments of the nail may be one-piece and include a proximal portion, a medial portion and a distal portion. The junction of the medial portion and distal portion is a bend that provides a small angle between the medial portion and the distal portion as viewed when the nail is substantially in a medial-lateral plane. The targeting assembly attaches to the proximal portion of the nail securely and enables easy insertion of fixing screws.

Abstract: Among other things, there are disclosed embodiments of an intramedullary nail system for use in pediatric cases, including an intramedullary nail and a targeting assembly. Embodiments of the nail may be one-piece and include a proximal portion, a medial portion and a distal portion. The junction of the medial portion and distal portion is a bend that provides a small angle between the medial portion and the distal portion as viewed when the nail is substantially in a medial-lateral plane. The targeting assembly attaches to the proximal portion of the nail securely and enables easy insertion of fixing screws.

Abstract: Disclosed herein are surface force microscope probes comprising living cells adhered thereto, as well as methods of making same. Also disclosed is a system for high throughput screening of nanostructures having biological relevance through use of surface force microscope probes comprising living cells. Further disclosed are methods of screening for biointeractive nanostructures.

Abstract: A modular knee implant system allows a surgeon to select between several different styles of distal femoral implant components and several different styles of stem extensions while also allowing for use of a metaphyseal component. The metaphyseal component can be a universal one that is usable with all of the styles of distal femoral implant components through use of an adapter. A second adapter allows for use of stem extensions with different types of connectors with the metaphyseal component. A separate metaphyseal component could also be provided with a distal Morse taper post to mate with a distal femoral component having a proximal Morse taper bore. The metaphyseal component may have an outer surface that is configured to maximize contact area with the patient's bone, and may have a surface finish over a substantial part of its overall length that is conducive to bone ingrowth.

Abstract: A modular knee implant system allows a surgeon to select between several different styles of distal femoral implant components and several different styles of stem extensions while also allowing for use of a metaphyseal component. The metaphyseal component can be a universal one that is usable with all of the styles of distal femoral implant components through use of an adapter. A second adapter allows for use of stem extensions with different types of connectors with the metaphyseal component. A separate metaphyseal component could also be provided with a distal Morse taper post to mate with a distal femoral component having a proximal Morse taper bore. The metaphyseal component may have an outer surface that is configured to maximize contact area with the patient's bone, and may have a surface finish over a substantial part of its overall length that is conducive to bone ingrowth.

Abstract: There are disclosed embodiments of screws for use in orthopedic surgery, particularly in pediatric patients. In some embodiments, inner and outer implantable members are provided, with the outer implantable member threadable on the inner implantable member to provide compression on two or more bone parts. In some embodiments, screw members are provided with a threaded shaft, and the thread continues into the head of the screw member to enable the thread to remain in pediatric bone.

Abstract: Disclosed herein are materials and methods for the efficient and universal fabrication of microcantilevers terminated with living cells. Methods disclosed describe the passive attachment of cells to microcantilevers that represent cells in suspension comprising living cells attached thereto via association with a hydrophobic layer. Also, disclosed are efficient methods for seeding single and multiple cells to cantilevers that represent isolated adherent cells and tissue constructs of tunable confluency.

Abstract: Described herein are composites that are relatively lightweight, high strength and low thermal conductivity. Also described herein are methods for the manufacture and use thereof.

Abstract: Disclosed herein are surface force microscope probes comprising living cells adhered thereto, as well as methods of making same. Also disclosed is a system for high throughput screening of nanostructures having biological relevance through use of surface force microscope probes comprising living cells. Further disclosed are methods of screening for biointeractive nanostructures.

Abstract: A modular long bone prosthesis is provided having a proximal component and a retroversion component. The proximal component is configured at a proximal end to receive a head forming a portion of a joint and is formed at a distal end to mate with additional prosthesis components. The proximal component is formed to simulate an angle inherent in the proximal end of the bone to be replaced and includes an indicator adjacent the distal end to facilitate rotational alignment of the proximal component and additional prosthesis components. The retroversion component includes a proximal end configured to mate with the distal end of the proximal component. The proximal end includes alignment indicia for positioning relative to the indicator on the proximal component.

Abstract: Two spacer components and a retaining ring are part of an orthopaedic system. The system may also include trial or implant stem components that are inserted or implanted in the proximal and distal ends of the long bone. One spacer segment has a male portion and the other spacer segment has a transverse female slot. The male portion and female slot are positioned to allow the male portion to be moved into and out of the female slot in a direction other than the proximal-distal direction. The retaining ring is then threaded into a locked position to limit relative movement between the male portion and female slot. The spacer segments can thus be connected after the segments have been connected to the native bone without damaging the soft tissue at the native bone through distraction.

Abstract: A system and method for automatically selecting a translator to translate a component request using semantic typing is presented. A mediator receives a component request from a first component that requests to invoke a second component. The mediator retrieves a launch target identifier and a requester provided property type identifier from the component request. The requester provided property type identifier includes semantic typing corresponding to a data value. The mediator retrieves a recipient input property type identifier corresponding to the launch target identifier, and uses the requester provided property type identifier and the recipient input property type identifier to select a translator. The mediator passes a data value included in the component request to the selected translator, and receives a translated data value from the translator. The mediator constructs a property using the translated data value and includes the constructed property in a call that is sent to the second component.

Abstract: A method and system for determining the wettability of particulate surfaces. In particular, the method for determining the wettability of particulate surface includes the steps of inserting a test device having the particulate surface into a test liquid to form a liquid meniscus; measuring the liquid meniscus to generate a liquid meniscus measurement; and calculating the wettability of the particulate surface using the liquid meniscus measurement. The system for determining the wettability of particulate surface includes a test device having the particulate surface; a test liquid; and a measurement device.