Abstract: Methods of using grids in connection with suitable microscopy techniques, such as for determining the structure of target compounds including proteins, are disclosed. Said grid comprising a coating modified with one or more capture agents and a deactivating agent.

Abstract: A compound having the following formula is disclosed. The compound is useful as an emitter in OLED applications.

Abstract: Substituted cyclohexyl chemical entities of Formula (I): wherein Ra, G, and Rb have any of the values described herein, and compositions comprising such chemical entities; methods of making them; and their use in a wide range of methods, including metabolic and reaction kinetic studies; detection and imaging techniques; radioactive therapies; modulating and treating disorders mediated by nociceptin activity or dopamine signaling; treating neurological disorders, neurodegenerative diseases, depression, and schizophrenia; enhancing the efficiency of cognitive and motor training; and treating peripheral disorders, including renal, respiratory, gastrointestinal, liver, genitourinary, metabolic, and inflammatory disorders.

Abstract: Foreign cells can be grown in fetal non-mammalian hosts for the production of transplant organs and tissues, the development of new therapeutic agents, and the production of biological factors and drugs. Tissue-specific injury to fetal host target cells is carried without substantial injury to the maternal host or foreign cells, providing an environment in which the injured tissue can be regenerated with the foreign cells.

Abstract: Foreign cells can be grown in fetal non-mammalian hosts for the production of transplant organs and tissues, the development of new therapeutic agents, and the production of biological factors and drugs. Tissue-specific injury to fetal host target cells is carried without substantial injury to the maternal host or foreign cells, providing an environment in which the injured tissue can be regenerated with the foreign cells.

Abstract: A chain ring gear set adapted for attaching to spider arms. The spider arms are attached to and extend outwardly from a bicycle gear crank. The ring gear set is adapted for receiving a bicycle chain thereon. The chain is transferred on the ring gear set using a chain derailer. The ring gear set includes a first ring gear disposed next to an adjacent second ring gear in a spaced relationship. A portion of the first ring gear is warped toward the second ring gear for periodically reducing the distance between a perimeter of the first ring gear to a perimeter of the second ring gear. Also, a portion of the second ring gear can be warped toward the first ring gear for sharing or combining the amount of warpage in each gear for reduced chain wear. By indexing the warped portion of the first ring gear with the warped portion of the second ring gear the overall distance periodically is reduced for ease in a smooth chain transfer between the gears.

Abstract: The invention is an improved rotary impact tool that uses a motor driven mechanism well known in the art as the Maurer mechanism comprising a hammer anvil frame and pins to cause impact loads applied through a rotary output shaft. The improvement is an improved striking surface geometry formed on the impact delivering jaw surface forming an involute profile generated from a base circle having an axis that is parallel to the axis of rotation of the output shaft.

Abstract: An ergonomically adjustable handle for attachment to the body of a tool has a handle member with first and second ends with an axis between. Provision for attaching the first end of the handle to the tool body allows rotation of the handle about the axis through the attachment point. A pivot point is located on the axis of the handle member near the first end and permits deflection of the second end of the handle with respect to the first end. In addition, an outer layer portion of the handle member near the second end may be rotated about its axis to provide a comfortable position for the ellipsoidal cross section of the handle. Finally, clamping provisions at the articulation point and the two rotation mechanisms secure the handle in the desired position.