Patents by Inventor Scott D. Pegan

Scott D. Pegan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CRIMEAN-CONGO HEMORRHAGIC FEVER VIRUS REPLICON PARTICLES AND USE THEREOF
    Publication number: 20220023410
    Abstract: Crimean-Congo hemorrhagic fever (CCHF) virus replicon particles (VRP) are described. These VRP are capable of undergoing a single round of virus replication, but are unable to produce new particles or spread to neighboring cells due to the lack of the glycoprotein-encoding M genome segment. In some instances, the VRP contain one or more mutations in the viral ovarian tumor domain protease encoded by the L genome segment or heterologous antigens within its S genome segment. The VRP are shown to elicit a protective immune response against lethal CCHF virus challenge in an animal model.
    Type: Application
    Filed: December 13, 2019
    Publication date: January 27, 2022
    Applicants: University of Georgia Research Foundation, Inc., THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Servic
    Inventors: Eric Bergeron, Scott D. Pegan, Stephen R. Welch, Florine E.M. Scholte, Christina F. Spiropoulou, Stuart T. Nichol, Jessica R. Spengler
  • Kir channel modulators
    Patent number: 8097422
    Abstract: Provided is a three-dimensional structure of an alcohol bound to an alcohol-binding site of an inwardly rectifying potassium (Kir) channel, Kir channel alcohol modulators and methods for identifying Kir channel modulators.
    Type: Grant
    Filed: June 17, 2008
    Date of Patent: January 17, 2012
    Assignee: Salk Institute for Biological Studies
    Inventors: Scott D. Pegan, Paul A. Slesinger, Senyon Choe, Prafulla Aryal
  • KIR CHANNEL MODULATORS
    Publication number: 20090148861
    Abstract: Provided is a three-dimensional structure of an alcohol bound to an alcohol-binding site of an inwardly rectifying potassium (Kir) channel, Kir channel alcohol modulators and methods for identifying Kir channel modulators.
    Type: Application
    Filed: June 17, 2008
    Publication date: June 11, 2009
    Applicant: THE SALK INSTITUTE
    Inventors: Scott D. Pegan, Paul A. Slesinger, Senyon Choe, Prafulla Aryal