Abstract: This invention relates to an improved method and composition for controlling all grades of acne vulgaris using a combination of sodium in the form of a pharmacologically acceptable sodium salt and an acne controlling compound selected from the group consisting of methyclothiazide, polythiazide and trichlormethazide, which is therapeutically effective in increasing sodium excretion in the sebaceous gland thereby controlling acne vulgaris eruptions. The conjoint use of the sodium salt and the acne controlling compound significantly reduces the unwanted side effects caused by the administration of the acne controlling compound including nausea, dizziness, hypotension and diuresis, which are experienced in some patients when the acne controlling compound is employed in acne treatment absent the conjoint use of the sodium salt.

Abstract: This invention is directed to the employment of a specific diuretic, methyclothiazide, in minimal dosage of 2.5 to 5.0 mg. per 48 hour period; preferably every other morning in conjunction with a daily dosage of an antibiotic tetracycline, in minimal dosage of 250 mg.daily; and, the unique method of treatment and administering these compounds.Acne vulgaris is divided into grades. This discovery is for the unique treatment and control of acne vulgaris grades 1, 11/2 and usually 2.