Abstract: 1,2-Dihydroxycyclohexa-3,5-diene-1,4-dicarboxylic acid and its salts, which are novel intermediates yielding hydroxyterephthalic acid upon dehydration, can be prepared by culturing terephthalic acid and a carbon/energy source with a microorganism capable of oxidizing terephthalic acid but incapable of degradation of 1,2-dihydroxycyclohexa-3,5-diene-1,4-dicarboxylic acid thereby formed.

Abstract: 1,2-Dihydroxycyclohexa-3,5-diene-1,4-dicarboxylic acid and its salts, which are novel intermediates yielding hydroxyterephthalic acid upon dehydration, can be prepared by culturing terephthalic acid and a carbon/energy source with a microorganism capable of oxidizing terephthalic acid but incapable of degradation of 1,2-dihydroxycyclohexa-3,5-diene-1,4-dicarboxylic acid thereby formed.

Abstract: This invention provides a process for the bioconversion of a non-growth aromatic feed to an accumulated quantity of 2-hydroxymuconic semialdehyde metabolite.2-Hydroxysemialdehyde is a useful intermediate for subsequent conversions to picolinic acid and pyridine.

Abstract: This invention provides a process for the bioconversion of a non-growth aromatic feed to an accumulated quantity of a 2-hydroxymuconic semialdehyde intermediate, which subsequently is converted by chemical means to picolinic acid and pyridine products.

Abstract: This invention provides novel mutant strains of microorganisms (e.g., Pseudomonas putida Biotype A) which are capable of converting substrates such as toluene, p-xylene, catechol and 4-methylcatechol to 2-hydroxymuconic semialdehyde or substituted analog of 2-hydroxymuconic semialdehyde quantitatively by the meta (catechol 2,3-oxygenase) pathway.No active 2-hydroxymuconic semialdehyde-metabolizing enzymes are induced in the microorganism, thereby permitting a 2-hydroxymuconic semialdehyde type metabolite to be produced and accumulated in a bioconversion medium containing the microorganism.

Abstract: The present invention provides a process for the production of p-cresol in a quantitative yield, which involves the acidification of an aqueous solution of 4-methylcyclohexa-3,5-diene-1,2-diol-1-carboxylic acid under ambient conditions of temperature and pressure to cause spontaneous decomposition of the starting material to p-cresol. The aqueous solution of 4-methylcyclohexa-3,5-diene-1,2-diol-1-carboxylic acid is produced by microbiological conversion of p-xylene with Pseudomonas putida Biotype A strain ATCC 39119.

Abstract: This invention provides a process for the bioconversion of a non-growth aromatic feed to an accumulated quantity of 2-hydroxymuconic semialdehyde metabolite.2-Hydroxysemialdehyde is a useful intermediate for subsequent conversions to picolinic acid and pyridine.

Abstract: The present invention provides a process for the production of p-cresol in a quantitative yield, which involves the acidification of an aqueous solution of the starting material, 4-methylcyclohexa-3,5-diene-1,2-diol-1-carboxylic acid, under ambient conditions of temperature and pressure to cause spontaneous decomposition of the starting material to p-cresol. The starting material is produced with Pseudomonas putida Biotype A strain ATCC 39119.

Abstract: The present invention provides a process for the production of p-cresol in a quantitative yield, which involves the acidification of an aqueous solution of 4-methylcyclohexa-3,5-diene-1,2-diol-1-carboxylic acid under ambient conditions of temperature and pressure to cause spontaneous decomposition of the starting material to p-cresol. The 4-methylcyclohexa-3,5-diene-1,2-diol-1-carboxylic acid is produced by the conversion of p-xylene with the microorganism, Pseudomonas putida Biotype A strain ATCC No. 39119.