Patents by Inventor Scott Hecker

Scott Hecker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tetracycline compositions
    Patent number: 11944634
    Abstract: The present invention relates to compositions, pharmaceutical compositions, and methods for preparing the same, comprising a tetracycline with improved stability and solubility. Some embodiments include a tetracycline with an excess of a divalent or trivalent cation.
    Type: Grant
    Filed: February 27, 2019
    Date of Patent: April 2, 2024
    Assignee: MELINTA SUBSIDIARY CORP.
    Inventors: David C. Griffith, Serge Boyer, Scott Hecker, Michael N. Dudley
  • Synthesis of boronate salts and uses thereof
    Patent number: 10669292
    Abstract: Disclosed herein are boronate intermediates in the synthesis of antimicrobial compounds and the use and preparation thereof. Some embodiments relate to crystalline boronate salt derivatives and their use in the synthesis of therapeutic compounds.
    Type: Grant
    Filed: August 2, 2019
    Date of Patent: June 2, 2020
    Assignee: REMPEX PHARMACEUTICALS, INC.
    Inventors: Scott Hecker, Serge Boyer
  • Cyclic boronic acid ester derivatives and therapeutic uses thereof
    Patent number: 10662205
    Abstract: Disclosed herein are antimicrobial compounds, compositions, pharmaceutical compositions, and the use and preparation thereof. Some embodiments relate to cyclic boronic acid ester derivatives and their use as therapeutic agents.
    Type: Grant
    Filed: November 13, 2015
    Date of Patent: May 26, 2020
    Assignee: QPEX BIOPHARMA, INC.
    Inventors: Scott Hecker, Raja K. Reddy, Tomasz Glinka
  • Therapeutic uses of pharmaceutical compositions comprising cyclic boronic acid ester derivatives
    Patent number: 10639318
    Abstract: Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to cyclic boronic acid ester derivatives and their use as therapeutic agents.
    Type: Grant
    Filed: November 13, 2018
    Date of Patent: May 5, 2020
    Assignee: REMPEX PHARMACEUTICALS, INC.
    Inventors: Gavin Hirst, Raja Reddy, Scott Hecker, Maxim Totrov, David C. Griffith, Olga Rodny, Michael N. Dudley, Serge Boyer
  • Substituted boronic acids as antimicrobials
    Patent number: 10618918
    Abstract: Disclosed herein are antimicrobial compounds having the structure of the formula III? pharmaceutical compositions, the use and preparation thereof. The compounds are of the class of boronic acid derivatives, useful for antimicrobial treatment.
    Type: Grant
    Filed: March 14, 2019
    Date of Patent: April 14, 2020
    Assignee: QPEX BIOPHARMA, INC.
    Inventors: Scott Hecker, Raja K. Reddy
  • SYNTHESIS OF BORONATE SALTS AND USES THEREOF
    Publication number: 20200031851
    Abstract: Disclosed herein are boronate intermediates in the synthesis of antimicrobial compounds and the use and preparation thereof. Some embodiments relate to crystalline boronate salt derivatives and their use in the synthesis of therapeutic compounds.
    Type: Application
    Filed: August 2, 2019
    Publication date: January 30, 2020
    Inventors: Scott HECKER, Serge BOYER
  • TETRACYCLINE COMPOSITIONS
    Publication number: 20200000828
    Abstract: The present invention relates to compositions, pharmaceutical compositions, and methods for preparing the same, comprising a tetracycline with improved stability and solubility. Some embodiments include a tetracycline with an excess of a divalent or trivalent cation.
    Type: Application
    Filed: February 27, 2019
    Publication date: January 2, 2020
    Inventors: David C. GRIFFITH, Serge BOYER, Scott HECKER, Michael N. DUDLEY
  • Synthesis of boronate salts and uses thereof
    Patent number: 10385074
    Abstract: Disclosed herein are boronate intermediates in the synthesis of antimicrobial compounds and the use and preparation thereof. Some embodiments relate to crystalline boronate salt derivatives and their use in the synthesis of therapeutic compounds.
    Type: Grant
    Filed: April 30, 2015
    Date of Patent: August 20, 2019
    Assignee: REMPEX PHARMACEUTICALS, INC.
    Inventors: Scott Hecker, Serge Boyer
  • BORONIC ACID DERIVATIVES AND THEIR THERAPEUTIC USES IN ANTIMICROBIAL TREATMENT
    Publication number: 20190211037
    Abstract: Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to boronic acid derivatives and their use as therapeutic agents.
    Type: Application
    Filed: March 14, 2019
    Publication date: July 11, 2019
    Inventors: Scott Hecker, Raja K. Reddy
  • POLYIMIDAZOLES FOR USE AS BILE ACID SEQUESTRANTS
    Publication number: 20190169342
    Abstract: The present invention provides crosslinked amine polymers effective for binding and removing bile salts from the gastrointestinal tract. These bile acid binding polymers or pharmaceutical compositions thereof can be administered to subjects to treat various conditions, including hypercholesteremia, diabetes, pruritus, irritable bowel syndrome-diarrhea (IBS-D), bile acid malabsorption, and the like.
    Type: Application
    Filed: February 8, 2019
    Publication date: June 6, 2019
    Inventors: Inez Lees, Kalpesh Biyani, Eric Connor, Scott Hecker, Hongmin Zhang, Michael James Cope, Elizabeth Goka, Angela Lee, Deidre Madsen, Jun Shao, Xinnan Zhang
  • Crosslinked polyvinylamine, polyallylamine, and polyethyleneimine for use as bile acid sequestrants
    Patent number: 10272103
    Abstract: The present invention provides a crosslinked amine and amide polymers effective for binding and removing bile salts from the gastrointestinal tract. These bile acid binding polymers or pharmaceutical compositions thereof can be administered to subjects to treat various conditions, including hypercholesteremia, diabetes, pruritis, irritable bowel syndrome-diarrhea (IBS-D), bile acid malabsorption, and the like.
    Type: Grant
    Filed: October 30, 2015
    Date of Patent: April 30, 2019
    Assignee: Relypsa, Inc.
    Inventors: Jordan Kopping, Paul Mansky, YongQi Mu, Michael James Cope, Elizabeth Goka, Angela Lee, Deidre Madsen, Jun Shao, Kalpesh Biyani, Eric Connor, Scott Hecker, Inez Lees, Grace May, Faleh Salaymeh, Hongmin Zhang, David Bergbreiter
  • CYCLIC BORONIC ACID ESTER DERIVATIVES AND THERAPEUTIC USES THEREOF
    Publication number: 20190084999
    Abstract: Disclosed herein are antimicrobial compounds, compositions, pharmaceutical compositions, and the use and preparation thereof. Some embodiments relate to cyclic boronic acid ester derivatives and their use as therapeutic agents.
    Type: Application
    Filed: November 13, 2015
    Publication date: March 21, 2019
    Inventors: Scott Hecker, Raja K. Reddy, Tomasz Glink
  • THERAPEUTIC USES OF PHARMACEUTICAL COMPOSITIONS COMPRISING CYCLIC BORONIC ACID ESTER DERIVATIVES
    Publication number: 20190076449
    Abstract: Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to cyclic boronic acid ester derivatives and their use as therapeutic agents.
    Type: Application
    Filed: November 13, 2018
    Publication date: March 14, 2019
    Inventors: Gavin Hirst, Raja Reddy, Scott Hecker, Maxim Totrov, David C. Griffith, Olga Rodny, Michael N. Dudley, Serge Boyer
  • Boronic acid derivatives and therapeutic uses thereof
    Patent number: 10206937
    Abstract: Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to boronic acid derivatives and their use as therapeutic agents.
    Type: Grant
    Filed: June 29, 2015
    Date of Patent: February 19, 2019
    Assignee: QPEX BIOPHARMA, INC.
    Inventors: Raja K. Reddy, Tomasz Glinka, Maxim Totrov, Scott Hecker, Olga Rodny
  • Therapeutic uses of pharmaceutical compositions comprising cyclic boronic acid ester derivatives
    Patent number: 10183034
    Abstract: Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to cyclic boronic acid ester derivatives and their use as therapeutic agents.
    Type: Grant
    Filed: March 26, 2018
    Date of Patent: January 22, 2019
    Assignee: Rempex Pharmaceuticals, Inc.
    Inventors: Gavin Hirst, Raja Reddy, Scott Hecker, Maxim Totrov, David C. Griffith, Olga Rodny, Michael N. Dudley, Serge Boyer
  • Pharmaceutical compositions comprising cyclic boronic acid ester derivatives
    Patent number: 10172874
    Abstract: Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to cyclic boronic acid ester derivatives and their use as therapeutic agents.
    Type: Grant
    Filed: March 26, 2018
    Date of Patent: January 8, 2019
    Assignee: REMPEX PHARMACEUTICALS, INC.
    Inventors: Gavin Hirst, Raja Reddy, Scott Hecker, Maxim Totrov, David C. Griffith, Olga Rodny, Michael N. Dudley, Serge Boyer
  • THERAPEUTIC USES OF PHARMACEUTICAL COMPOSITIONS COMPRISING CYCLIC BORONIC ACID ESTER DERIVATIVES
    Publication number: 20180214465
    Abstract: Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to cyclic boronic acid ester derivatives and their use as therapeutic agents.
    Type: Application
    Filed: March 26, 2018
    Publication date: August 2, 2018
    Inventors: Gavin Hirst, Raja Reddy, Scott Hecker, Maxim Totrov, David C. Griffith, Olga Rodny, Michael N. Dudley, Serge Boyer
  • PHARMACEUTICAL COMPOSITIONS COMPRISING CYCLIC BORONIC ACID ESTER DERIVATIVES
    Publication number: 20180207183
    Abstract: Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to cyclic boronic acid ester derivatives and their use as therapeutic agents.
    Type: Application
    Filed: March 26, 2018
    Publication date: July 26, 2018
    Inventors: Gavin Hirst, Raja Reddy, Scott Hecker, Maxim Totrov, David C. Griffith, Olga Rodny, Michael N. Dudley, Serge Boyer
  • Cyclic boronic acid ester derivatives and methods of making the same
    Patent number: 10004758
    Abstract: Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to cyclic boronic acid ester derivatives and their use as therapeutic agents.
    Type: Grant
    Filed: June 15, 2017
    Date of Patent: June 26, 2018
    Assignee: Rempex Pharmaceuticals, Inc.
    Inventors: Gavin Hirst, Raja Reddy, Scott Hecker, Maxim Totrov, David C. Griffith, Olga Rodny, Michael N. Dudley, Serge Boyer
  • Boronic acid derivatives and therapeutic uses thereof
    Patent number: 9963467
    Abstract: Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to boronic acid derivatives and their use as therapeutic agents.
    Type: Grant
    Filed: May 18, 2015
    Date of Patent: May 8, 2018
    Assignee: Rempex Pharmaceuticals, Inc.
    Inventors: Raja Reddy, Tomasz Glinka, Scott Hecker, Maxim Totrov, Olga Rodny