Patents by Inventor Scott L. Butler
Scott L. Butler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 10837059Abstract: A method for detecting nucleic acids by (a) providing a sample having target nucleic acids, each nucleic acid having contiguous first, second, and third domains; (b) contacting the sample with probe sets to form hybridization complexes, wherein each probe set includes (i) a first probe having a sequence that is complementary to the first domain; and (ii) a second probe having a sequence substantially complementary to the third domain; (c) extending the first probes along the second domains of the complexes while the complexes are immobilized on a solid support; (d) ligating the extended first probes to the second probes to form templates; (e) amplifying the templates with primers that are complementary to the first and second priming sequences to produce amplicons; and (f) detecting the amplicons on the surface of a nucleic acid array.Type: GrantFiled: November 30, 2017Date of Patent: November 17, 2020Assignee: Illumina, Inc.Inventors: Arnold Oliphant, John R. Stuelpnagel, Mark S. Chee, Scott L. Butler, Jian-Bing Fan, Min-Jui Richard Shen
-
Publication number: 20180094316Abstract: A method for detecting nucleic acids by (a) providing a sample having target nucleic acids, each nucleic acid having contiguous first, second, and third domains; (b) contacting the sample with probe sets to form hybridization complexes, wherein each probe set includes (i) a first probe having a sequence that is complementary to the first domain; and (ii) a second probe having a sequence substantially complementary to the third domain; (c) extending the first probes along the second domains of the complexes while the complexes are immobilized on a solid support; (d) ligating the extended first probes to the second probes to form templates; (e) amplifying the templates with primers that are complementary to the first and second priming sequences to produce amplicons; and (f) detecting the amplicons on the surface of a nucleic acid array.Type: ApplicationFiled: November 30, 2017Publication date: April 5, 2018Inventors: Arnold Oliphant, John R. Stuelpnagel, Mark S. Chee, Scott L. Butler, Jian-Bing Fan, Min-Jui Richard Shen
-
Patent number: 9850536Abstract: A method for detecting nucleic acids by (a) providing a sample having target nucleic acids, each nucleic acid having contiguous first, second, and third domains; (b) contacting the sample with probe sets to form hybridization complexes, wherein each probe set includes (i) a first probe having a sequence that is complementary to the first domain; and (ii) a second probe having a sequence substantially complementary to the third domain; (c) extending the first probes along the second domains of the complexes while the complexes are immobilized on a solid support; (d) ligating the extended first probes to the second probes to form templates; (e) amplifying the templates with primers that are complementary to the first and second priming sequences to produce amplicons; and (f) detecting the amplicons on the surface of a nucleic acid array.Type: GrantFiled: November 13, 2014Date of Patent: December 26, 2017Assignee: Illumina, Inc.Inventors: Arnold Oliphant, John R. Stuelpnagel, Mark S. Chee, Scott L. Butler, Jian-Bing Fan, Min-Jui Richard Shen
-
Publication number: 20150203913Abstract: A method for detecting nucleic acids by (a) providing a sample having target nucleic acids, each nucleic acid having contiguous first, second, and third domains; (b) contacting the sample with probe sets to form hybridization complexes, wherein each probe set includes (i) a first probe having a sequence that is complementary to the first domain; and (ii) a second probe having a sequence substantially complementary to the third domain; (c) extending the first probes along the second domains of the complexes while the complexes are immobilized on a solid support; (d) ligating the extended first probes to the second probes to form templates; (e) amplifying the templates with primers that are complementary to the first and second priming sequences to produce amplicons; and (f) detecting the amplicons on the surface of a nucleic acid array.Type: ApplicationFiled: November 13, 2014Publication date: July 23, 2015Applicant: ILLUMINA, INC.Inventors: Arnold Oliphant, John R. Stuelpnagel, Mark S. Chee, Scott L. Butler, Jian-Bing Fan, Min-Jui Richard Shen
-
Patent number: 8906626Abstract: A method for detecting nucleic acids by (a) providing a sample having target nucleic acids, each nucleic acid having contiguous first, second, and third domains; (b) contacting the sample with probe sets to form hybridization complexes, wherein each probe set includes (i) a first probe having a sequence that is complementary to the first domain; and (ii) a second probe having a sequence substantially complementary to the third domain; (c) extending the first probes along the second domains of the complexes while the complexes are immobilized on a solid support; (d) ligating the extended first probes to the second probes to form templates; (e) amplifying the templates with primers that are complementary to the first and second priming sequences to produce amplicons; and (f) detecting the amplicons on the surface of a nucleic acid array.Type: GrantFiled: September 6, 2012Date of Patent: December 9, 2014Assignee: Illumina, Inc.Inventors: Arnold Oliphant, John R. Stuelpnagel, Mark S. Chee, Scott L. Butler, Jian-Bing Fan, Min-Jui Richard Shen
-
Publication number: 20130244882Abstract: A method for detecting nucleic acids by (a) providing a sample having target nucleic acids, each nucleic acid having contiguous first, second, and third domains; (b) contacting the sample with probe sets to form hybridization complexes, wherein each probe set includes (i) a first probe having a sequence that is complementary to the first domain; and (ii) a second probe having a sequence substantially complementary to the third domain; (c) extending the first probes along the second domains of the complexes while the complexes are immobilized on a solid support; (d) ligating the extended first probes to the second probes to form templates; (e) amplifying the templates with primers that are complementary to the first and second priming sequences to produce amplicons; and (f) detecting the amplicons on the surface of a nucleic acid array.Type: ApplicationFiled: September 6, 2012Publication date: September 19, 2013Applicant: ILLUMINA, INC.Inventors: Arnold Oliphant, John R. Stuelpnagel, Mark S. Chee, Scott L. Butler, Jian-Bing Fan, Min-Jui Richard Shen
-
Patent number: 8288103Abstract: The invention is directed to a variety of multiplexing methods used to amplify and/or genotype a variety of samples simultaneously.Type: GrantFiled: May 28, 2010Date of Patent: October 16, 2012Assignee: Illumina, Inc.Inventors: Arnold Oliphant, John R. Stuelpnagel, Mark S. Chee, Scott L. Butler, Jian-Bing Fan, Min-Jui Richard Shen
-
Patent number: 8003354Abstract: The invention is directed to a variety of multiplexing methods used to amplify and/or genotype a variety of samples simultaneously.Type: GrantFiled: February 15, 2008Date of Patent: August 23, 2011Assignee: Illumina, Inc.Inventors: Min-Jui Richard Shen, Arnold Oliphant, Scott L. Butler, John R. Stuelpnagel, Mark S. Chee, Kenneth M. Kuhn, Jian-Bing Fan
-
Patent number: 7955794Abstract: The invention is directed to a variety of multiplexing methods used to amplify and/or genotype a variety of samples simultaneously.Type: GrantFiled: June 20, 2002Date of Patent: June 7, 2011Assignee: Illumina, Inc.Inventors: Mun-Jui Richard Shen, Arnold Oliphant, Scott L. Butler, John E. Stuelpnagel, Mark S. Chee, Kenneth M. Kuhn, Jian-Bing Fan
-
Publication number: 20100311064Abstract: The invention is directed to a variety of multiplexing methods used to amplify and/or genotype a variety of samples simultaneously.Type: ApplicationFiled: May 28, 2010Publication date: December 9, 2010Applicant: Illumina, Inc.Inventors: Arnold Oliphant, John R. Stuelpnagel, Mark S. Chee, Scott L. Butler, Jian-Bing Fan, Min-Jui Richard Shen
-
Publication number: 20100015626Abstract: The invention is directed to a variety of multiplexing methods used to amplify and/or genotype a variety of samples simultaneously.Type: ApplicationFiled: July 21, 2009Publication date: January 21, 2010Applicant: Illumina, Inc.Inventors: Arnold Oliphant, John R. Stuelpnagel, Mark S. Chee, Scott L. Butler, Jian-Bing Fan, Min-Jui Richard Shen
-
Patent number: 7582420Abstract: The invention is directed to a variety of multiplexing methods used to amplify and/or genotype a variety of samples simultaneously.Type: GrantFiled: July 12, 2002Date of Patent: September 1, 2009Assignee: Illumina, Inc.Inventors: Arnold Oliphant, John R. Stuelpnagel, Mark S. Chee, Scott L. Butler, Jian-Bing Fan, Min-Jui Richard Shen
-
Publication number: 20080242555Abstract: The invention is directed to a variety of multiplexing methods used to amplify and/or genotype a variety of samples simultaneously.Type: ApplicationFiled: February 15, 2008Publication date: October 2, 2008Applicant: Illumina, Inc.Inventors: Min-Jui Richard Shen, Arnold Oliphant, Scott L. Butler, John R. Stuelpnagel, Mark S. Chee, Kenneth M. Kuhn, Jian-Bing Fan
-
Publication number: 20030211489Abstract: The invention is directed to a variety of multiplexing methods used to amplify and/or genotype a variety of samples simultaneously.Type: ApplicationFiled: June 20, 2002Publication date: November 13, 2003Inventors: Min-Jui Richard Shen, Arnold Oliphant, Scott L. Butler, John R. Stuelpnagel, Mark S. Chee, Kenneth M. Kuhn, Jian-Bing Fan
-
Publication number: 20030108900Abstract: The invention is directed to a variety of multiplexing methods used to amplify and/or genotype a variety of samples simultaneously.Type: ApplicationFiled: July 12, 2002Publication date: June 12, 2003Inventors: Arnold Oliphant, John R. Stuelpnagel, Mark S. Chee, Scott L. Butler