Patents by Inventor Scott Macdonnell

Scott Macdonnell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI- PDGF-B ANTIBODIES AND METHODS OF USE FOR TREATING PULMONARY ARTERIAL HYPERTENSION (PAH)
    Publication number: 20220242943
    Abstract: The present disclosure provides anti-Platelet-Derived Growth Factor Subunit B (PDGF-B) antibodies, and antigen-binding fragments thereof, as well as methods of use of such antibodies, or antigen-binding fragments thereof, for treating a subject having pulmonary arterial hypertension (PAH).
    Type: Application
    Filed: January 25, 2022
    Publication date: August 4, 2022
    Inventors: Yinglin Gao, Scott Macdonnell, Bharathi Sundaram, Jee Kim, Isabella Del Priore, Jake Megna, Qin Ruan
  • Methods for Preventing and Treating Cardiac Dysfunction and COVID-19 with Activin A Antagonists
    Publication number: 20220056119
    Abstract: The present invention provides methods for preventing and treating cardiac dysfunction, including cardiomyopathy and heart failure. The methods of the invention feature the administration of an antagonist of Activin A, e.g., a therapeutically effective amount of an antibody that binds to and reduces or neutralizes the activity of human Activin A. The methods of the invention are useful in preventing and treating cardiac disease from multiple causes, including viral disease, e.g., COVID-19.
    Type: Application
    Filed: August 19, 2021
    Publication date: February 24, 2022
    Inventors: David Glass, Scott Macdonnell, Jake Megna, Lori Morton