Abstract: A method of motor control device emulation includes receiving, via a network-enabled motor control device, a communication request corresponding to an emulated motor control device. The method further includes modifying the communication request to match an expected communication request. Additionally, the method includes providing a modified communication request to an associated hardware module within the network-enabled motor control device. Further, the expected communication request is based on the network-enabled motor control device.

Abstract: A three dimensional printing system, the system including: a printhead; and a removable tray comprising a reservoir, the tray located in a print bed of the three dimensional printing system such that liquid purged from the printhead is deposited in the reservoir, wherein prior to the system purging liquid from the printhead, the system confirms that the tray is in place using a sensor.

Abstract: Provided herein are methods of treating cancer using an antibody or antigen-binding fragments thereof that specifically bind to human ENTPD2 protein, and compositions comprising these antibodies or antigen-binding fragments for use in the treatment of cancer. The present invention also relates to combination therapies comprising an anti-human ENTPD2 antibody or antigen binding fragment and at least one additional therapeutic agent, and methods of using these combination therapies.

Abstract: Provided herein are combinations comprising an antibody or antigen-binding fragment thereof, e.g., a monoclonal antibody or antigen binding fragment thereof, that specifically binds to ENTPD2 (e.g., human ENTPD2 protein), and an antibody or antigen-binding fragment thereof, e.g., a monoclonal antibody or antigen binding fragment thereof, that specifically binds to CD73 (e.g., human CD73 protein), and methods of using these combinations.

Abstract: Two, standard dimension, Si wafers, one <111>-oriented and the other <100>-oriented for example, are bonded together to form a two-ply substrate. Such an Si double-wafer substrate is stiffer than either a double-thickness <111>-oriented or <100>-oriented wafer. C-beveling on the two constituent wafers results in a B-bevel edge of the two-ply substrate that does not create stress risers. Also, standard thickness wafers are commercially available. GaN epitaxial layer is then grown on this two-ply substrate.

Abstract: Advanced display devices are integrated into glasses so that they look and feel more like normal glasses. They are based on pupil replication using multiple, small projectors. A number of projectors are embedded in the eyeglasses, for example embedded in the rim of the eyeglasses or in a periphery of the lens. The projectors generate (partial) images based on a common image to be displayed to the user. These images are optically coupled through the lens, for example using waveguide coupling, to different display windows in the lens. The display windows couple the images out of the lens and towards the user's eye.

Abstract: In one approach, an LED array uses a combination of a half cavity and straight reflective sidewalls to improve the power distribution so that more light falls within the collection angle of the projection optics. From the bottom upwards, the LEDs in the array include a reflector, a thinner p-layer and a thicker n-layer. An active region (such as quantum wells) between the p-layer and the p-layer generates light. Without additional structures, the generated light would have an isotropic distribution and not much of the light would fall within the collection angle of the projection optics. However, the bottom reflector and p-layer form a half cavity for the light emitted from the active region. This alters the angular power distribution. Straight reflective sidewalls extending from the active region upwards into the n-layer further reflect light from the altered power distribution into the collection angle of the projection optics.

Abstract: An enterprise resource data store may contain electronic records, each electronic record representing an enterprise resource entry, and including, for each entry, an electronic record identifier and a set of enterprise values. A series query data store may contain electronic records, each electronic record representing a series query, and including, for each series query, an electronic record identifier and a set of pre-defined single query parameters. A back-end application computer server may receive, from a remote user device, a selected series query. The server may then retrieve, from the series query data store, information about a selected set of pre-defined single query parameters including comparison period data. In addition, the server may retrieve, from the enterprise resource data store, information about enterprise resource entries associated with the selected set and comparison period data. The server may then arrange to output an indication of step analysis results and analysis notes.

Abstract: Electrical connectors for very high speed signals, including signals at or above 112 Gbps. Effectiveness of shielding along the signal paths through the mating electrical connectors may be enhanced through the use of one or more techniques, including enabling two-sided shielding, connections between shield members and between shield members and grounded structures of printed circuit boards to which the connectors are mounted, and selective positioning of lossy material. Such techniques may be simply and reliably implemented in high density connector using one or more techniques. An electrical connector may include core members held by a housing together with leadframe assemblies attached to the core members. The core members may include features that would be difficult to mold in a housing and may include both shields and lossy materials in locations that would be difficult to incorporate in a leadframe assembly.

Abstract: A direct mate orthogonal connector for a high density of high speed signals. The connector may include right angle leadframe assemblies with signal conductive elements and ground shields held by a leadframe housing. High frequency performance may be achieved with members on the leadframe that transfer force between a connector housing, holding the leadframe assemblies, and a portion of the leadframe housing holding the signal conductive elements and the shields near their mounting ends. Core members may be inserted into the housing and mating ends of the conductive elements of ground shields may be adjacent the core members, enabling electrical and mechanical performance of the mating interface to be defined by the core members. The core members may incorporate insulative and lossy features that may be complex to form as part of the connector housing but may be readily formed as part of a separate core member.

Abstract: The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical compositions comprising these compounds, and use of the compounds and compositions in therapy.

Abstract: A device for training users in a proper mixing of pharmaceutical components, or for aiding in the mixing, or for performing the mixing, and administration of pharmaceutical components is disclosed. The device comprises a housing for receiving a pharmaceutical delivery device containing the pharmaceutical components. There is also a microcontroller disposed in the housing and a motion/orientation detection device disposed within or on the housing and in communication with the microcontroller. A method for use of the device is also disclosed, along with a substance for use as one of the pharmaceutical components.

Abstract: The present disclosure relates generally to a telecommunications patch panel comprising a connector module and a frame member. The connector module has a front face and an opposite facing rear face. The front face includes a connector jack for receiving a plug of a first conductive wire. The rear face includes a connection location for connecting to a second conductive wire. The connector module defines an axis of rotation generally parallel to the front face. The frame member has a front face and a plurality of tabs on the front face. The connector module is rotatably mounted to the frame member for movement about the rotation axis, and the plurality of tabs engage with the rear face of the connector module to prevent over-rotation of the connector module.

Abstract: Disclosed are fluidic devices and methods for preparing fluidic devices. More particularly, disclosed are fluidic devices having fiber scaffolds and methods for their preparation. Also disclosed are methods for culturing cells using the fluidic devices having fiber scaffolds.

Abstract: An internal combustion engine having an intake manifold, a compressor in fluid communication with the intake manifold, a charge air cooler in fluid communication with and between the compressor and the intake manifold, a throttle controlling fluid communication between the air charge cooler and the intake manifold, and a condensate collection reservoir that collects condensate from the air charge cooler and is in fluid communication with a suction port of a Venturi device in a bypass loop around the throttle. A motive inlet of the Venturi device is in fluid communication upstream of the throttle and a discharge outlet is in fluid communication downstream of the throttle, and under operating conditions that provide an adequate pressure drop across the Venturi device, the suction port draws condensate from the condensate collection reservoir and introduces the condensate into the intake manifold as a mist.

Abstract: An auto-injector may include a housing having a longitudinal axis and a transverse axis, the housing having a shorter dimension along the transverse axis than along the longitudinal axis, wherein the transverse axis is perpendicular to the longitudinal axis; a flowpath having a first end and a second end; and a container enclosing a first fluid, the container extending from a first end toward a second end along or parallel to the longitudinal axis and being movable from a first position to a second position along or parallel to the longitudinal axis, the container being fluidly isolated from the flowpath in the first position and fluidly connected to the flowpath in the second position.

Abstract: An aspect of the present disclosure is directed to a connector. The connector is suited to connectorizing exactly two conductors. The connector includes a forward connector body, a rear connector body, a metal frame and exactly two electrical contacts. The rear connector body interfaces with the forward connector body. Further, the metal frame, which includes a shielding interface, surrounds at least a portion of both the forward and rear connector bodies. The electrical contacts extend from the rear connector body into the forward connector body. A first of the electrical contacts is electrically coupled to a first conductor of a shielded cable and the second of the electrical contacts is electrically coupled to a second conductor of the shielded cable. The shield interface of the metal frame is electrically coupled to the shield of the shielded cable.

Abstract: The present application is directed to a double seam modification tooling apparatus for double seam modification and the double seam modification process. More particularly, a tooling apparatus for double seam modification is provided which adds a third modification operation to the first and second double seam operations which form the finished double seam, as well as a process for modifying double seams to include patterns of integral slots, notches or threads, or the like, after the double seams have been previously completely formed by the double seam modification tooling apparatus. Child resistant lids can then be configured with mating tab notches or tab threads to allow for opening or closing the lid when the tabs are properly aligned with the notches and threads on the can rim modified double seams.

Abstract: An auto-injector may include a housing having a longitudinal axis and a transverse axis, the housing having a shorter dimension along the transverse axis than along the longitudinal axis, wherein the transverse axis is perpendicular to the longitudinal axis; a flowpath having a first end and a second end; and a container enclosing a first fluid, the container extending from a first end toward a second end along or parallel to the longitudinal axis and being movable from a first position to a second position along or parallel to the longitudinal axis, the container being fluidly isolated from the flowpath in the first position and fluidly connected to the flowpath in the second position.