Patents by Inventor Scott Youmans
Scott Youmans has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220105030Abstract: Methods are provided for acutely treating migraine headache with or without aura. The methods comprise administering to a subject with migraine headache an effective dose of a liquid pharmaceutical composition comprising dihydroergotamine (DHE) or a salt thereof, wherein the dose is administered by an intranasal delivery device that provides, following intranasal administration, (a) a mean peak plasma DHE concentration (Cmax) of at least 750 pg/ml, (b) with a mean time to Cmax(Tmax) of DHE of less than 45 minutes, and (c) a mean plasma AUC0-inf of DHE of at least 2500 pg*hr/ml. Also provided are kits for acutely treating migraine with or without aura in which a liquid pharmaceutical composition comprising DHE or DHE salt is contained within a sealed vial that is attachable to a precision intranasal olfactory delivery device packaged therewith.Type: ApplicationFiled: October 1, 2021Publication date: April 7, 2022Inventors: John D. Hoekman, Kelsey H. Satterly, Stephen B. Shrewsbury, Scott Youmans, Christopher Fuller
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Patent number: 11185497Abstract: Methods are provided for acutely treating migraine headache with or without aura. The methods comprise administering to a subject with migraine headache an effective dose of a liquid pharmaceutical composition comprising dihydroergotamine (DHE) or a salt thereof, wherein the dose is administered by an intranasal delivery device that provides, following intranasal administration, (a) a mean peak plasma DHE concentration (Cmax) of at least 750 pg/ml, (b) with a mean time to Cmax (Tmax) of DHE of less than 45 minutes, and (c) a mean plasma AUC0-inf of DHE of at least 2500 pg*hr/ml. Also provided are kits for acutely treating migraine with or without aura in which a liquid pharmaceutical composition comprising DHE or DHE salt is contained within a sealed vial that is attachable to a precision intranasal olfactory delivery device packaged therewith.Type: GrantFiled: October 2, 2020Date of Patent: November 30, 2021Assignee: Impel Neuropharma, Inc.Inventors: John D. Hoekman, Kelsey H. Satterly, Stephen B. Shrewsbury, Scott Youmans, Christopher Fuller
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Publication number: 20210236485Abstract: Methods are provided for reducing the frequency of migraine attacks in a subject who has frequent migraine headaches with or without aura. The methods comprise intranasally administering to the subject a pharmaceutical composition comprising dihydroergotamine (DHE) or salt thereof on a repeat dose schedule, wherein each intranasal administration is delivered by a manually actuated, propellant-driven, metered-dose administration device, and wherein the schedule is a chronic intermittent schedule in which each of the repeated administrations is performed while the subject is experiencing a migraine headache.Type: ApplicationFiled: January 13, 2021Publication date: August 5, 2021Inventors: John D. Hoekman, Kelsey H. Satterly, Stephen B. Shrewsbury, Scott Youmans, Christopher Fuller
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Publication number: 20210022995Abstract: Methods are provided for acutely treating migraine headache with or without aura. The methods comprise administering to a subject with migraine headache an effective dose of a liquid pharmaceutical composition comprising dihydroergotamine (DHE) or a salt thereof, wherein the dose is administered by an intranasal delivery device that provides, following intranasal administration, (a) a mean peak plasma DHE concentration (Cmax) of at least 750 pg/ml, (b) with a mean time to Cmax (Tmax) of DHE of less than 45 minutes, and (c) a mean plasma AUC0-inf of DHE of at least 2500 pg*hr/ml. Also provided are kits for acutely treating migraine with or without aura in which a liquid pharmaceutical composition comprising DHE or DHE salt is contained within a sealed vial that is attachable to a precision intranasal olfactory delivery device packaged therewith.Type: ApplicationFiled: October 2, 2020Publication date: January 28, 2021Inventors: John D. Hoekman, Kelsey H. Satterly, Stephen B. Shrewsbury, Scott Youmans, Christopher Fuller
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Patent number: 10869956Abstract: An interventional catheter assembly comprising a catheter for insertion and guidance to a target site in a body lumen or a cavity and an operating head mounted in proximity to a distal end of the catheter and comprising a system for removing obstructive material from the target site is provided. In certain embodiments, the catheter assembly includes at least one aspiration port located proximal to the operating head that communicates with a first sealed lumen for withdrawing fluids and obstructive material from the target site. The catheter assembly may also include at least one liquid infusion port that communicates with a second sealed lumen for supplying fluid to a location in proximity to the target site. Kits including the interventional catheter assembly with an aspiration and/or infusion conduit are also provided.Type: GrantFiled: June 6, 2018Date of Patent: December 22, 2020Assignee: BOSTON SCIENTIFIC LIMITEDInventors: Casey Torrance, Kate Walsh, Jared Salstrom, Scott Youmans, Edward I. Wulfman
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Publication number: 20190209463Abstract: Methods are provided for acutely treating migraine headache with or without aura. The methods comprise administering to a subject with migraine headache an effective dose of a liquid pharmaceutical composition comprising dihydroergotamine (DHE) or a salt thereof, wherein the dose is administered by an intranasal delivery device that provides, following intranasal administration, (a) a mean peak plasma DHE concentration (Cmax) of at least 750 pg/ml, (b) with a mean time to Cmax (Tmax) of DHE of less than 45 minutes, and (c) a mean plasma AUC0-inf of DHE of at least 2500 pg*hr/ml. Also provided are kits for acutely treating migraine with or without aura in which a liquid pharmaceutical composition comprising DHE or DHE salt is contained within a sealed vial that is attachable to a precision intranasal olfactory delivery device packaged therewith.Type: ApplicationFiled: January 4, 2019Publication date: July 11, 2019Inventors: John D. Hoekman, Kelsey H. Satterly, Stephen B. Shrewsbury, Scott Youmans, Christopher Fuller
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Patent number: 10149698Abstract: An interventional catheter assembly has an operating head and catheter system that are inserted and navigated within a patient's body while an operator controls the system externally of the operating head. An operating head is positioned at or near a distal end of the catheter system and coupled to a drive shaft and drive system for rotation. A guidewire brake control system interrupt prevents the drive system from being actuated when the guidewire brake is in a released position, and a selectable guidewire brake interrupt override control permits an operator to translate and/or rotate the drive shaft and operating head while the guidewire is simultaneously moved. This allows withdrawal of the guide wire and the operating head from the target site while rotating the operating head.Type: GrantFiled: February 10, 2015Date of Patent: December 11, 2018Assignee: BOSTON SCIENTIFIC LIMITEDInventors: Edward I. Wulfman, Casey Torrance, Brian Cran, Scott Youmans
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Publication number: 20180280594Abstract: An interventional catheter assembly comprising a catheter for insertion and guidance to a target site in a body lumen or a cavity and an operating head mounted in proximity to a distal end of the catheter and comprising a system for removing obstructive material from the target site is provided. In certain embodiments, the catheter assembly includes at least one aspiration port located proximal to the operating head that communicates with a first sealed lumen for withdrawing fluids and obstructive material from the target site. The catheter assembly may also include at least one liquid infusion port that communicates with a second sealed lumen for supplying fluid to a location in proximity to the target site. Kits including the interventional catheter assembly with an aspiration and/or infusion conduit are also provided.Type: ApplicationFiled: June 6, 2018Publication date: October 4, 2018Applicant: BOSTON SCIENTIFIC LIMITEDInventors: CASEY TORRANCE, KATE WALSH, JARED SALSTROM, SCOTT YOUMANS, EDWARD I. WULFMAN
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Patent number: 10010657Abstract: An interventional catheter assembly comprising a catheter for insertion and guidance to a target site in a body lumen or a cavity and an operating head mounted in proximity to a distal end of the catheter and comprising a system for removing obstructive material from the target site is provided. In certain embodiments, the catheter assembly includes at least one aspiration port located proximal to the operating head that communicates with a first sealed lumen for withdrawing fluids and obstructive material from the target site. The catheter assembly may also include at least one liquid infusion port that communicates with a second sealed lumen for supplying fluid to a location in proximity to the target site. Kits including the interventional catheter assembly with an aspiration and/or infusion conduit are also provided.Type: GrantFiled: February 24, 2016Date of Patent: July 3, 2018Assignee: Boston Scientific LimitedInventors: Casey Torrance, Kate Walsh, Jared Salstrom, Scott Youmans, Edward I. Wulfman
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Publication number: 20160166743Abstract: An interventional catheter assembly comprising a catheter for insertion and guidance to a target site in a body lumen or a cavity and an operating head mounted in proximity to a distal end of the catheter and comprising a system for removing obstructive material from the target site is provided. In certain embodiments, the catheter assembly includes at least one aspiration port located proximal to the operating head that communicates with a first sealed lumen for withdrawing fluids and obstructive material from the target site. The catheter assembly may also include at least one liquid infusion port that communicates with a second sealed lumen for supplying fluid to a location in proximity to the target site. Kits including the interventional catheter assembly with an aspiration and/or infusion conduit are also provided.Type: ApplicationFiled: February 24, 2016Publication date: June 16, 2016Applicant: BOSTON SCIENTIFIC LIMITEDInventors: CASEY TORRANCE, KATE WALSH, JARED SALSTROM, SCOTT YOUMANS, EDWARD I. WULFMAN
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Patent number: 9295373Abstract: An interventional catheter assembly comprising a catheter for insertion and guidance to a target site in a body lumen or a cavity and an operating head mounted in proximity to a distal end of the catheter and comprising a system for removing obstructive material from the target site is provided. In certain embodiments, the catheter assembly includes at least one aspiration port located proximal to the operating head that communicates with a first sealed lumen for withdrawing fluids and obstructive material from the target site. The catheter assembly may also include at least one liquid infusion port that communicates with a second sealed lumen for supplying fluid to a location in proximity to the target site. Kits including the interventional catheter assembly with an aspiration and/or infusion conduit are also provided.Type: GrantFiled: February 12, 2014Date of Patent: March 29, 2016Assignee: BOSTON SCIENTIFIC LIMITEDInventors: Casey Torrance, Kate Walsh, Jared Salstrom, Scott Youmans, Edward I. Wulfman
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Publication number: 20150164542Abstract: An interventional catheter assembly has an operating head and catheter system that are inserted and navigated within a patient's body while an operator controls the system externally of the operating head. An operating head is positioned at or near a distal end of the catheter system and coupled to a drive shaft and drive system for rotation. A guidewire brake control system interrupt prevents the drive system from being actuated when the guidewire brake is in a released position, and a selectable guidewire brake interrupt override control permits an operator to translate and/or rotate the drive shaft and operating head while the guidewire is simultaneously moved. This allows withdrawal of the guide wire and the operating head from the target site while rotating the operating head.Type: ApplicationFiled: February 10, 2015Publication date: June 18, 2015Applicant: BOSTON SCIENTIFIC LIMITEDInventors: EDWARD I. WULFMAN, CASEY TORRANCE, BRIAN CRAN, SCOTT YOUMANS
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Patent number: 8951224Abstract: An interventional catheter assembly has an operating head and catheter system that are inserted and navigated within a patient's body while an operator controls the system externally of the operating head. An operating head is positioned at or near a distal end of the catheter system and coupled to a drive shaft and drive system for rotation. A guidewire brake control system interrupt prevents the drive system from being actuated when the guidewire brake is in a released position, and a selectable guidewire brake interrupt override control permits an operator to translate and/or rotate the drive shaft and operating head while the guidewire is simultaneously moved. This allows withdrawal of the guide wire and the operating head from the target site while rotating the operating head.Type: GrantFiled: November 30, 2012Date of Patent: February 10, 2015Assignee: Boston Scientific LimitedInventors: Edward I. Wulfman, Casey Torrance, Brian Cran, Scott Youmans
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Publication number: 20140163384Abstract: An interventional catheter assembly comprising a catheter for insertion and guidance to a target site in a body lumen or a cavity and an operating head mounted in proximity to a distal end of the catheter and comprising a system for removing obstructive material from the target site is provided. In certain embodiments, the catheter assembly includes at least one aspiration port located proximal to the operating head that communicates with a first sealed lumen for withdrawing fluids and obstructive material from the target site. The catheter assembly may also include at least one liquid infusion port that communicates with a second sealed lumen for supplying fluid to a location in proximity to the target site. Kits including the interventional catheter assembly with an aspiration and/or infusion conduit are also provided.Type: ApplicationFiled: February 12, 2014Publication date: June 12, 2014Inventors: Casey TORRANCE, Kate WALSH, Jared SALSTROM, Scott YOUMANS, Edward I. WULFMAN
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Patent number: 8657785Abstract: An interventional catheter assembly comprising a catheter for insertion and guidance to a target site in a body lumen or a cavity and an operating head mounted in proximity to a distal end of the catheter and comprising a system for removing obstructive material from the target site is provided. In certain embodiments, the catheter assembly includes at least one aspiration port located proximal to the operating head that communicates with a first sealed lumen for withdrawing fluids and obstructive material from the target site, together with at least one liquid infusion port penetrating the catheter and located proximal to the at least one aspiration port that communicates with a second sealed lumen for supplying fluid to a location in proximity to the target site.Type: GrantFiled: November 30, 2010Date of Patent: February 25, 2014Assignee: Bayer Medical Care Inc.Inventors: Casey Torrance, Kate Walsh, Jared Salstrom, Scott Youmans, Edward I. Wulfman
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Publication number: 20130345676Abstract: An interventional catheter assembly has an operating head and catheter system that are inserted and navigated within a patient's body while an operator controls the system externally of the operating head. An operating head is positioned at or near a distal end of the catheter system and coupled to a drive shaft and drive system for rotation. A guidewire brake control system interrupt prevents the drive system from being actuated when the guidewire brake is in a released position, and a selectable guidewire brake interrupt override control permits an operator to translate and/or rotate the drive shaft and operating head while the guidewire is simultaneously moved. This allows withdrawal of the guide wire and the operating head from the target site while rotating the operating head.Type: ApplicationFiled: November 30, 2012Publication date: December 26, 2013Applicant: MEDRAD, INC.Inventors: Edward I. WULFMAN, Casey TORRANCE, Brian CRAN, Scott YOUMANS
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Patent number: 8544193Abstract: A snowshoe with binding suspended by tension straps secured to a frame is assembled from a generally U-shaped nose, and an aft section which can be a midsection and a tail. In one embodiment the nose has sufficient strength to resist inward pulling under tension to suspend the binding resiliently, without significant strength contribution from aft portions of the frame. The aft portion of the snowshoe includes traction elements, i.e. rows of teeth, positioned to engage into snow and ice. An important aspect of the invention is that the nose and aft sections are non-integral and very dissimilar in cross section, in a suspended-binding snowshoe.Type: GrantFiled: November 12, 2010Date of Patent: October 1, 2013Assignee: K-2 CorporationInventors: Dodd Grande, Chris Barchet, Jay Bublitz, Scott Youmans
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Patent number: 8474158Abstract: A molded or plastic composite snowshoe is formed of two assembled sections, in a way that imparts flexibility to the snowshoe, allowing some degree of torsional twisting or warping flexibility so that the snowshoe adapts to uneven terrain. In a principal embodiment the molded snowshoe is divided into forward and aft sections along a line slightly behind the nose area and near the pivot axis in the case of a pitch-pivoting binding. Joints between sections are in narrow rims at left and right, at opposed sides of a large central opening for the crampon/binding and boot. The joints are designed to securely hold the forward and aft molded sections together but to allow a degree of torsion between them when needed. Steel structural traction rails extend across the joints but are constructed and secured to the snowshoe sections in a manner that preserves the desired flexibility.Type: GrantFiled: January 21, 2010Date of Patent: July 2, 2013Assignee: K-2 CorporationInventors: Rudy Lucas Samuels, Chris Barchet, Dodd Grande, Rachel Lin, Mark S. Williams, Scott Youmans
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Publication number: 20120117827Abstract: A snowshoe with binding suspended by tension straps secured to a frame is assembled from a generally U-shaped nose, and an aft section which can be a midsection and a tail. In one embodiment the nose has sufficient strength to resist inward pulling under tension to suspend the binding resiliently, without significant strength contribution from aft portions of the frame. The aft portion of the snowshoe includes traction elements, i.e. rows of teeth, positioned to engage into snow and ice. An important aspect of the invention is that the nose and aft sections are non-integral and very dissimilar in cross section, in a suspended-binding snowshoe.Type: ApplicationFiled: November 12, 2010Publication date: May 17, 2012Inventors: Dodd Grande, Chris Barchet, Jay Bublitz, Scott Youmans
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Patent number: 8171658Abstract: A snowshoe of molded plastic material has a tail section with greater flexibility than the main body section, thereby allowing the tail to give and deform as the snowshoe tail is engaged against the terrain during the gait of the user. At the same time, the tail is stiff enough to provide flotation needed when the full weight of the user is on one snowshoe fully engaged against terrain, such as soft snow.Type: GrantFiled: November 24, 2008Date of Patent: May 8, 2012Assignee: K-2 CorporationInventors: Rudy Lucas Samuels, Chris Barchet, Dodd Grande, Mark S. Williams, Scott Youmans, Rachel Lin