Abstract: Microfluidic devices, assemblies, and systems are provided, as are methods of manipulating micro-sized samples of fluids. Microfluidic devices having a plurality of specialized processing features are also provided.

Abstract: A fluid processing device comprises a substrate rotatable about a central axis of rotation and symmetrical about at least one centerline passing through the central axis of rotation, and the substrate comprises a plurality of channels, each channel comprising a respective inlet chamber and two or more respective outlet chambers. The chambers can include a plurality of individual, unconnected, input wells adapted to each receive a separate input of fluid. The channels can include flow splitters that divert at least a portion of fluid from a primary series of channels and chambers to a secondary series of channels and chambers. The diverting portions of the flow splitters can comprise at least a directional component parallel to the direction of centrifugal forces generated by rotating the substrate about its central axis of rotation.

Abstract: The present invention provides products and methods of reducing dye artifacts from chain extension reactions.

Abstract: A device, system, and method are provided for thermally treating a fluid processing device. According to various embodiments, a system is provided that can include a thermal device and a fluid processing device holder. The thermal device can include a first block having a thermal conductivity greater than 0.5 Watt per centimeter Kelvin (W/cm·K), a second block having a thermal conductivity greater than 0.5 W/cm·K, and a heat-pump device disposed between the first block and the second block. The heat-pump device can transfer thermal energy from at least one of the first block and the second block to the other of the first block and the second block. The fluid processing device holder can hold a fluid processing device in a heat-transfer position with respect to the first block and the second block. The fluid processing device can be a microfluidic device.

Abstract: A capillary array assembly is provided that can be used to inject samples into an electrophoresis device. The capillary array assembly can include an injection end that can be arranged to interface with output wells of a fluid processing device, for example, a microfluidic card-type device.

Abstract: Microfluidic devices, assemblies, and systems are provided, as are methods of manipulating micro-sized samples of fluids. Microfluidic devices having a plurality of specialized processing features that facilitate centripetal fluid transfer are also provided.

Abstract: Apparatus and method for loading a channel device for electrophoretic separation including cilia which can be deflected into wells of a multi-well tray.

Abstract: A machine-readable medium is described having code stored thereon which defines an integrated circuit (IC), the IC comprising: a host processor to process data and perform address calculations associated with the data; and a peripheral address generation unit (“PAGU”) to offload specified types of the address calculations from the host processor.