Patents by Inventor Sean TOENJES

Sean TOENJES has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Atropisomerism for increased kinase inhibitor selectivity
    Patent number: 11345707
    Abstract: The invention provides a series of conformationally stable kinase inhibitors, and methods of using the kinase inhibitors. The effect of atropisomerism on kinase selectivity was assessed, finding improved selectivity compared to rapidly interconverting parent compounds.
    Type: Grant
    Filed: December 18, 2019
    Date of Patent: May 31, 2022
    Assignee: San Diego State University (SDSU) Foundation
    Inventors: Jeffrey L. Gustafson, Davis E. Smith, David Hecht, Isaac Marquez, Sean Toenjes
  • ATROPISOMERISM FOR INCREASED KINASE INHIBITOR SELECTIVITY
    Publication number: 20200131191
    Abstract: The invention provides a series of conformationally stable kinase inhibitors, and methods of using the kinase inhibitors. The effect of atropisomerism on kinase selectivity was assessed, finding improved selectivity compared to rapidly interconverting parent compounds.
    Type: Application
    Filed: December 18, 2019
    Publication date: April 30, 2020
    Applicant: SAN DIEGO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventors: Jeffrey L. GUSTAFSON, Davis E. SMITH, David HECHT, Isaac MARQUEZ, Sean TOENJES
  • Atropisomerism for increased kinase inhibitor selectivity
    Patent number: 10550124
    Abstract: The invention provides a series of conformationally stable kinase inhibitors, and methods of using the kinase inhibitors. The effect of atropisomerism on kinase selectivity was assessed, finding improved selectivity compared to rapidly interconverting parent compounds.
    Type: Grant
    Filed: August 15, 2016
    Date of Patent: February 4, 2020
    Assignee: San Diego State University Foundation
    Inventors: Jeffrey L. Gustafson, Davis E. Smith, David Hecht, Isaac Marquez, Sean Toenjes
  • ATROPISOMERISM FOR INCREASED KINASE INHIBITOR SELECTIVITY
    Publication number: 20180230154
    Abstract: The invention provides a series of conformationally stable kinase inhibitors, and methods of using the kinase inhibitors. The effect of atropisomerism on kinase selectivity was assessed, finding improved selectivity compared to rapidly interconverting parent compounds.
    Type: Application
    Filed: August 15, 2016
    Publication date: August 16, 2018
    Applicant: SAN DIEGO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventors: Jeffrey L. GUSTAFSON, Davis E. SMITH, David HECHT, Isaac MARQUEZ, Sean TOENJES