Patents by Inventor Sebastiano Mangiafico

Sebastiano Mangiafico has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tropicamide-based ophthalmic formulations
    Patent number: 11382901
    Abstract: An ophthalmic composition includes tropicamide, at least one cyclodextrin at concentrations of less than 2.5%, at least one surfactant at concentrations of less than 2.5%. The composition is physically stable at neutral pH.
    Type: Grant
    Filed: June 20, 2018
    Date of Patent: July 12, 2022
    Assignee: FOR HEALTH PHARMA S.R.L.
    Inventor: Sebastiano Mangiafico
  • TROPICAMIDE-BASED OPHTHALMIC FORMULATIONS
    Publication number: 20210137900
    Abstract: An ophthalmic composition includes tropicamide, at least one cyclodextrin at concentrations of less than 2.5%, at least one surfactant at concentrations of less than 2.5%. The composition is physically stable at neutral pH.
    Type: Application
    Filed: June 20, 2018
    Publication date: May 13, 2021
    Inventor: Sebastiano MANGIAFICO
  • Ophthalmic, intra-articular or intravesical preparations containing N-acyl-ethanolamines
    Patent number: 9668986
    Abstract: It is the object of the present invention a composition containing an N-acyl-ethanolamine in a solubilized form, particularly a solution for ophthalmic, intra-articular or intravesical use. Particularly, the present invention relates to a water-soluble composition comprising one or more N-acylethanolamines (NAE) in the form of an inclusion complex in methyl-beta-cyclodextrin (M?CD).
    Type: Grant
    Filed: March 2, 2015
    Date of Patent: June 6, 2017
    Assignee: EPITECH GROUP S.R.L.
    Inventors: Francesco Della Valle, Sebastiano Mangiafico, Maria Federica Della Valle
  • OPHTHALMIC, INTRA-ARTICULAR OR INTRAVESICAL PREPARATIONS CONTAINING N-ACYL-ETHANOLAMINES
    Publication number: 20150265551
    Abstract: It is the object of the present invention a composition containing an N-acyl-ethanolamine in a solubilized form, particularly a solution for ophthalmic, intra-articular or intravesical use. Particularly, the present invention relates to a water-soluble composition comprising one or more N-acylethanolamines (NAE) in the form of an inclusion complex in methyl-beta-cyclodextrin (M?CD).
    Type: Application
    Filed: March 2, 2015
    Publication date: September 24, 2015
    Applicant: EPITECH GROUP S.R.I.
    Inventors: Francesco DELLA VALLE, Sebastiano MANGIAFICO, Maria Federica DELLA VALLE
  • Process for the preparation of 1-(3-trifluoromehylphenyl)-propan-2-ol enantiomers
    Patent number: 6987205
    Abstract: A process for the preparation of 1-(3-trifluoromethylphenyl)-propan-2-ol enantiomersthrough enzymatic resolution by a lipase.
    Type: Grant
    Filed: January 10, 2002
    Date of Patent: January 17, 2006
    Assignees: Fidia Farmaceutici S.p.A., Consiglio Nazionale Delle Ricerche
    Inventors: Giovanni Nicolosi, Sebastiano Mangiafico, Nicola D'Antona
  • Process for the preparation of 1-(3-trifluoromehylphenyl) -propan-2-ol enantiomers
    Publication number: 20050176119
    Abstract: A process for the preparation of 1-(3-trifluoromethylphenyl)-propan-2-ol enantiomersthrough enzymatic resolution by a lipase.
    Type: Application
    Filed: January 10, 2002
    Publication date: August 11, 2005
    Inventors: Giovanni Nicolosi, Sebastiano Mangiafico, Nicola D'Antona
  • Treatment of ophthalmic disorders
    Publication number: 20050054586
    Abstract: Pharmaceutical compositions comprising coumarin bases and salts thereof are useful for treat various ophthalmic disorders. The active ingredient includes cloricromene or its hydrochloride salt.
    Type: Application
    Filed: June 24, 2004
    Publication date: March 10, 2005
    Inventors: Stephen Bartels, Sebastiano Mangiafico