Patents by Inventor Sebastien Cirou
Sebastien Cirou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9174145Abstract: The invention concerns a bag comprising a first conduit (13J), a second conduit (13K), the first section (13J1) of the first conduit (13J) and the first section (13K1) of the second conduit (13K) being opposite; a third conduit (13L) linking said first respective ends (13J2, 13K2) of said first respective sections (13J1, 13K1); a fourth conduit (13M) linking said second respective ends (13J3, 13K3) of said first respective sections (13J1, 13K1); a fifth conduit (13N) linking both said second end (13J3) of said first section (13J1) and said first end (13M1) of said fourth conduit (13M), and said fifth conduit (13N) linking both said first end (13K2) and said second end (13L2) of said third conduit (13L); said first conduit (13J) and said second conduit (13K) each being connected to a chromatography column connector (11M).Type: GrantFiled: June 16, 2011Date of Patent: November 3, 2015Assignee: EMD Millipore CorporationInventors: Jean-Louis Weissenbach, Sebastien Cirou, Virginie Buisson
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Patent number: 9174772Abstract: The invention concerns a device comprising a base; a circuit comprising a bag comprising two flexible films and conveying network connectors, and a press (9) comprising a first shell (16) disposed upright on a front face (5) of said base (2) and a second shell (17) mounted on said first shell (16), said first shell (16) and second shell (17) clamping said bag to form conduits; said bag comprising first through apertures on one side and said first shell (16) comprising hooking studs (106) on an upper part, which studs (106) pass through said first apertures.Type: GrantFiled: June 6, 2011Date of Patent: November 3, 2015Assignee: EMD Millipore CorporationInventors: Sebastien Cirou, Rene Reinbigler, Virginie Buisson, Jean-Louis Weissenbach
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Publication number: 20150204450Abstract: The invention concerns a circuit comprising a bag (11) comprising two flexible films (45, 46) and a press (10) comprising a first (14) and a second (13) shell clamping the bag to form pipes having a passage and edges (41); the first shell comprising a valve (20) which comprises a movable member (24) and a pad (31), which pad has a resting configuration in which a second face (33) of the pad is concave and locally delimits a channel (18) and a pinching configuration in which the second face (33) is convex; said movable member and said pad being configured so that, when said valve is in closed position and said pad in pinching configuration, said passage is pinched by said movable member against said second shell channel and said edges (41) are pinched flat by said movable member against said second shell (13).Type: ApplicationFiled: July 18, 2013Publication date: July 23, 2015Inventors: Ronald Tuccelli, Sebastien Cirou, Virginie Buisson, Christine Abouayad El Idrissi, Jim Kelly
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Publication number: 20150190809Abstract: The invention concerns a device comprising a circuit comprising a bag (10) comprising two flexible films (65, 66), a press (9) comprising a first shell (16) disposed upright on a front face of a base of the device and a second shell (17) mounted on said first shell, which shells clamp said bag to form conduits (13); said press is provided with a system (170) for jamming at the location of a treatment zone (67) of the bag, which comprises a jamming member (171) provided with at least one jamming nipple (173) and a complementary jamming member (172) provided with a jamming channel (174) configured to receive said nipple; said jamming member (171) and complementary jamming member (172) and said bag (10) being configured in order for the latter to have a portion (175) in said treatment zone in which said films are jammed between said nipple and said channel.Type: ApplicationFiled: July 18, 2013Publication date: July 9, 2015Inventors: Ronald Tuccelli, Sebastien Cirou, Virginie Buisson, Christine Abouayad El Idrissi, Jim Kelly
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Patent number: 9051929Abstract: The invention concerns a circuit comprising a bag (111) comprising two flexible films (145, 146) and routing network connectors, and a press (110) comprising a first shell (114) and a second shell (113) clamping the bag to form pipes (104) between the films, the first shell comprising a pinch valve (120) which comprises an actuator (121) comprising a movable member (124) and in register with the moveable member an elastically compressible pad (131) which, when the valve is in an open position, has a resting configuration in which a second face (33) of the pad is concave and locally delimits a shaping channel (118), and, when the valve is in a closed position, has a pinching configuration in which the second face (133) is convex, with the pipe and the pad sandwiched between a shaping channel (116) and the moveable member.Type: GrantFiled: January 11, 2011Date of Patent: June 9, 2015Assignee: EMD Millipore CorporationInventors: Sebastien Cirou, Jean-Louis Weissenbach
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Publication number: 20150020366Abstract: The invention concerns a filtration device comprising a manifold providing fluid connection and mechanical connection comprising a clamping plate movably mounted relative to the manifold and adapted to compress at least one cassette against the manifold, means for driving and guiding the clamping plate comprising a rod extending between the manifold and the plate, an actuator provided with a body and a member moveable relative to the body, which member is adapted to move through a predetermined travel between an extended position and a retracted position, the body being carried by the manifold, and the member carrying the rod and driving the plate via the rod to a clamped position in which the member is in an intermediate retracted position in which it has moved through a shorter travel than the predetermined travel relative to its extended position.Type: ApplicationFiled: October 6, 2014Publication date: January 22, 2015Inventors: Sebastien Cirou, Jean-Louis Weissenbach, Rene Reinbigler, Jean-Luc Beulay, Frans Mels, Cecile Delbos
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Publication number: 20150013773Abstract: The invention concerns a device comprising: a base (2); a moveable or removable door (20), said device having a closed door position; and in the closed door position, a circuit (8) comprising a bag comprising two flexible films and conveying network connectors, and a press (9) comprising a first shell (16) disposed on said front face (5) of said base (2) and a second shell (17) disposed in said door (20); said bag being clamped between said first shell (16) and said second shell (17) in a state in which conduits of said network for conveying liquid are formed between said films.Type: ApplicationFiled: September 23, 2014Publication date: January 15, 2015Inventors: Sebastien Cirou, Rene Reinbigler, Virginie Buisson, Jean-Louis Weissenbach
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Publication number: 20150008184Abstract: The invention concerns a device comprising a base (2) and a door (20), said device having a closed door position in which a circuit (8) of the device comprises a bag comprising two flexible films and connectors of the conveying network, and a press (9) comprising a first she (16) disposed on a front face (5) of said base (2) and a second shed (17) disposed in said door (20); and a hinge system hinging said door (20) relative to said base (2), and disposed only on one side of said door (20) so as to form lateral clearances between said door (20) and said base (2) over the rest of a perimeter of said door (20)Type: ApplicationFiled: September 23, 2014Publication date: January 8, 2015Inventors: Sebastien Cirou, Rene Reinbigler, Virginie Buisson, Jean-Louis Weissenbach
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Patent number: 8921096Abstract: The invention concerns a pump cart for a biological liquid treatment installation, having a first lateral face (40), and a second lateral face (41) by which it is configured to be juxtaposed against a conveying network cart (1) of the installation and a front face (42) meeting the lateral faces (40, 41), and comprising at least one pump (414), a pump support (50) on which is mounted said pump (414), and a guide member for making said pump (414) movable in translation and on which said support (50) is mounted; said support (50) being movable in translation in a direction going from the first lateral face (40) towards the second lateral face (41); whereby said pump (414) is disposed at a predetermined location on said cart (2) depending on the type of treatment carried out.Type: GrantFiled: July 21, 2011Date of Patent: December 30, 2014Assignee: EMD Millipore CorporationInventors: Jean-Louis Weissenbach, Rene Reinbigler, Virginie Buisson, Christine Abouayad El Idrissi, Sebastien Cirou
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Patent number: 8906229Abstract: The invention concerns a device comprising: a base (2); a moveable or removable door (20), said device having a closed door position; and in the closed door position, a circuit (8) comprising a bag comprising two flexible films and conveying network connectors, and a press (9) comprising a first shell (16) disposed on said front face (5) of said base (2) and a second shell (17) disposed in said door (20); said bag being clamped between said first shell (16) and said second shell (17) in a state in which conduits of said network for conveying liquid are formed between said films.Type: GrantFiled: May 26, 2011Date of Patent: December 9, 2014Assignee: EMD Millipore CorporationInventors: Sebastien Cirou, Rene Reinbigler, Virginie Buisson, Jean-Louis Weissenbach
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Patent number: 8900454Abstract: The invention concerns a device comprising a base (2) and a door (20), said device having a closed door position in which a circuit (8) of the device comprises a bag comprising two flexible films and connectors of the conveying network, and a press (9) comprising a first shell (16) disposed on a front face (5) of said base (2) and a second shell (17) disposed in said door (20); and a hinge system hinging said door (20) relative to said base (2), and disposed only on one side of said door (20) so as to form lateral clearances between said door (20) and said base (2) over the rest of a perimeter of said door (20).Type: GrantFiled: June 6, 2011Date of Patent: December 2, 2014Assignee: EMD Millipore CorporationInventors: Sebastien Cirou, Rene Reinbigler, Virginie Buisson, Jean-Louis Weissenbach
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Patent number: 8883003Abstract: The invention concerns a filtration device comprising a manifold (3) providing fluid connection and mechanical connection comprising a clamping plate (4) movably mounted relative to the manifold (3) and adapted to compress at least one cassette (2) against the manifold (3), means for driving and guiding the clamping plate comprising a rod (6) extending between the manifold (3) and the plate (4), an actuator provided with a body and a member moveable relative to the body, which member is adapted to move through a predetermined travel between an extended position and a retracted position, the body being carried by the manifold (3), and the member carrying the rod (6) and driving the plate (4) via the rod (6) to a clamped position in which the member is in an intermediate retracted position in which it has moved through a shorter travel than the predetermined travel relative to its extended position.Type: GrantFiled: July 25, 2013Date of Patent: November 11, 2014Assignee: EMD Millipore CorporationInventors: Sebastien Cirou, Jean-Louis Weissenbach, Rene Reinbigler, Jean-Luc Beulay, Frans Mels, Cecile Delbos
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Patent number: 8877052Abstract: The invention concerns a filtration device comprising a manifold (3) providing fluid connection and mechanical connection comprising a clamping plate (4) movably mounted relative to the manifold (3) and adapted to compress at least one cassette (2) against the manifold (3), means for driving and guiding the clamping plate comprising a rod (6) extending between the manifold (3) and the plate (4), an actuator provided with a body and a member moveable relative to the body, which member is adapted to move through a predetermined travel between an extended position and a retracted position, the body being carried by the manifold (3), and the member carrying the rod (6) and driving the plate (4) via the rod (6) to a clamped position in which the member is in an intermediate retracted position in which it has moved through a shorter travel than the predetermined travel relative to its extended position.Type: GrantFiled: May 12, 2011Date of Patent: November 4, 2014Assignee: EMD Millipore CorporationInventors: Sebastien Cirou, Jean-Louis Weissenbach, Rene Reinbigler, Jean-Luc Beulay, Frans Mels, Cecile Delbos
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Publication number: 20140299530Abstract: The invention concerns a filtration device comprising a providing fluid connection and mechanical connection comprising a clamping plate movably mounted relative to the manifold and adapted to compress at least one cassette against the manifold, means for driving and guiding the clamping plate comprising a rod extending between the manifold and the plate, an actuator provided with a body and a member moveable relative to the body, which member is adapted to move through a predetermined travel between an extended position and a retracted position, the body being carried by the manifold, and the member carrying the rod and driving the plate via the rod to a clamped position in which the member is in an intermediate retracted position in which it has moved through a shorter travel than the predetermined travel relative to its extended position.Type: ApplicationFiled: June 23, 2014Publication date: October 9, 2014Inventors: Sebastien Cirou, Jean-Louis Weissenbach, Rene Reinbigler, Jean-Luc Beulay, Frans Mels, Cecile Delbos
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Publication number: 20140299531Abstract: The invention concerns a filtration device comprising a manifold providing fluid connection and mechanical connection comprising a clamping plate movably mounted relative to the manifold and adapted to compress at least one cassette against the manifold, means for driving and guiding the clamping plate comprising a rod extending between the manifold and the plate, an actuator provided with a body and a member moveable relative to the body, which member is adapted to move through a predetermined travel between an extended position and a retracted position, the body being carried by the manifold, and the member carrying the rod and driving the plate via the rod to a clamped position in which the member is in an intermediate retracted position in which it has moved through a shorter travel than the predetermined travel relative to its extended position.Type: ApplicationFiled: June 23, 2014Publication date: October 9, 2014Inventors: Sebastien Cirou, Jean-Louis Weissenbach, Rene Reinbigler, Jean-Luc Beulay, Frans Mels, Cecile Delbos
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Patent number: 8701704Abstract: The invention concerns a manifold comprising: an auxiliary block (3) having cassette feed ports (20) and cassette filtrate return ports (21) each emerging through a bearing surface (7) and, on a counter-bearing surface (8) situated on the opposite side to the bearing surface (7), first recesses into each of which emerges a cassette filtrate return port (21); a main block (2) on which is fastened the auxiliary block (3), having an inlet conduit (14) and a filtrate outlet conduit (15), cassette feed intermediate ports which communicate with the inlet conduit (14) and with a cassette feed port (20), conveying cut-outs each facing a recess, and cassette filtrate return intermediate ports which communicate with the filtrate outlet conduit (15) and with a cassette filtrate return port (21).Type: GrantFiled: May 12, 2011Date of Patent: April 22, 2014Assignee: EMD Millipore CorporationInventors: Sebastien Cirou, Jean-Louis Weissenbach, Rene Reinbigler, Jean-Luc Beulay, Frans Mels, Cecile Delbos
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Publication number: 20140069537Abstract: The invention concerns a circuit comprising a bag (111) comprising two flexible films (145, 146) and routing network connectors, and a press (110) comprising a first shell (114) and a second shell (113) clamping the bag to form pipes (104) between the films, the first shell comprising a pinch valve (120) which comprises an actuator (121) comprising a movable member (124) and in register with the moveable member an elastically compressible pad (131) which, when the valve is in an open position, has a resting configuration in which a second face (33) of the pad is concave and locally delimits a shaping channel (118), and, when the valve is in a closed position, has a pinching configuration in which the second face (133) is convex, with the pipe and the pad sandwiched between a shaping channel (116) and the moveable member.Type: ApplicationFiled: November 15, 2013Publication date: March 13, 2014Applicant: EMD Millipore CorporationInventors: Sebastien Cirou, Jean-Louis Weissenbach
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Publication number: 20130306539Abstract: The invention concerns a filtration device comprising a manifold (3) providing fluid connection and mechanical connection comprising a clamping plate (4) movably mounted relative to the manifold (3) and adapted to compress at least one cassette (2) against the manifold (3), means for driving and guiding the clamping plate comprising a rod (6) extending between the manifold (3) and the plate (4), an actuator provided with a body and a member moveable relative to the body, which member is adapted to move through a predetermined travel between an extended position and a retracted position, the body being carried by the manifold (3), and the member carrying the rod (6) and driving the plate (4) via the rod (6) to a clamped position in which the member is in an intermediate retracted position in which it has moved through a shorter travel than the predetermined travel relative to its extended position.Type: ApplicationFiled: July 25, 2013Publication date: November 21, 2013Applicant: EMD Millipore CorporationInventors: Sebastien Cirou, Jean-Louis Weissenbach, Rene Reinbigler, Jean-Luc Beulay, Frans Mels, Cecile Delbos
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Patent number: 8557113Abstract: The cart comprises a lateral face by which it is adapted to be juxtaposed against another cart. It further comprises a first pump, a second pump disposed below said first pump and laterally offset relative thereto, and a tank adapted to receive a feed container provided to contain said biological liquid, said tank being disposed above said first pump and offset laterally relative thereto. The installation comprises one said cart, a filter and a second cart, juxtaposed against said first cart and of which the upper face supports said filter such that an outlet point of said first pump is situated substantially facing an inlet/outlet aperture of said filter.Type: GrantFiled: December 4, 2009Date of Patent: October 15, 2013Assignee: EMD Millipore CorporationInventors: Jean Luc Beulay, Virginie Buisson, Sebastien Cirou, Cecile Delbos, Marc Hlavacek, Frans Mels, Rene Reinbigler, Jean Louis Weissenbach
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Publication number: 20130240065Abstract: The invention concerns a bag comprising a first conduit (13C) which extends longitudinally between a flow pump connector (11C) emerging on a first side (68) and a tangential filter connector (11M) emerging on a second side (69); a second conduit (13B) which extends longitudinally from a first side of said conduit (13C) between a supply container connector (11B) emerging on said first side (68), and another tangential flow connector (11N) emerging on said second side (69); a third conduit (13H) which extends from a second side of said conduit (13C), starting at a collecting container connector (11J), until it enters said first conduit (13C); and a fourth conduit (13A) which extends from the first side of said conduit (13C), starting at a transfer pump connector (11A), until it enters said second conduit (13B).Type: ApplicationFiled: May 8, 2013Publication date: September 19, 2013Applicant: EMD Millipore CorporationInventors: Jean-Louis Weissenbach, Sebastien Cirou